(20 nodes) Positive regulation of transforming growth factor beta receptor signaling pathway network (Poecilia reticulata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdkn2b	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (126 aa)
	LOC103482005	E1A binding protein p300 a. (2743 aa)
	ENSPREP00000030224	PID domain-containing protein. (124 aa)
	SMAD4	Mothers against decapentaplegic homolog. (439 aa)
	snw1	SNW domain containing 1. (536 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
	LOC103468460	E1A binding protein p300 b. (2737 aa)
	gipc2	GIPC PDZ domain containing family, member 2. (329 aa)
	LOC103477474	Mothers against decapentaplegic homolog. (534 aa)
	LOC103473773	Mothers against decapentaplegic homolog. (503 aa)
	hsp90ab1	Heat shock protein 90, alpha (cytosolic), class B member 1. (723 aa)
	flcn	Folliculin. (554 aa)
	crebbp	CREB binding protein b. (2452 aa)
	ENSPREP00000009700	Uncharacterized protein. (280 aa)
	ENSPREP00000009672	Uncharacterized protein. (343 aa)
	LOC103468782	GIPC PDZ domain containing family, member 1. (335 aa)
	men1	Multiple endocrine neoplasia I. (627 aa)
	clg14h20orf27	Si:ch211-74f19.2. (174 aa)
	ENSPREP00000004616	Uncharacterized protein. (91 aa)
	LOC103464091	CREB binding protein a. (2371 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464091	LOC103468460	ENSPREP00000000408	ENSPREP00000026558	CREB binding protein a.	E1A binding protein p300 b.	0.928
LOC103464091	LOC103473773	ENSPREP00000000408	ENSPREP00000020499	CREB binding protein a.	Mothers against decapentaplegic homolog.	0.521
LOC103464091	LOC103477474	ENSPREP00000000408	ENSPREP00000022544	CREB binding protein a.	Mothers against decapentaplegic homolog.	0.521
LOC103464091	LOC103482005	ENSPREP00000000408	ENSPREP00000030842	CREB binding protein a.	E1A binding protein p300 a.	0.928
LOC103464091	SMAD4	ENSPREP00000000408	ENSPREP00000027467	CREB binding protein a.	Mothers against decapentaplegic homolog.	0.521
LOC103464091	snw1	ENSPREP00000000408	ENSPREP00000027074	CREB binding protein a.	SNW domain containing 1.	0.686
LOC103468460	LOC103464091	ENSPREP00000026558	ENSPREP00000000408	E1A binding protein p300 b.	CREB binding protein a.	0.928
LOC103468460	LOC103473773	ENSPREP00000026558	ENSPREP00000020499	E1A binding protein p300 b.	Mothers against decapentaplegic homolog.	0.592
LOC103468460	LOC103477474	ENSPREP00000026558	ENSPREP00000022544	E1A binding protein p300 b.	Mothers against decapentaplegic homolog.	0.596
LOC103468460	LOC103482005	ENSPREP00000026558	ENSPREP00000030842	E1A binding protein p300 b.	E1A binding protein p300 a.	0.902
LOC103468460	SMAD4	ENSPREP00000026558	ENSPREP00000027467	E1A binding protein p300 b.	Mothers against decapentaplegic homolog.	0.592
LOC103468460	crebbp	ENSPREP00000026558	ENSPREP00000011232	E1A binding protein p300 b.	CREB binding protein b.	0.992
LOC103468460	hsp90ab1	ENSPREP00000026558	ENSPREP00000012481	E1A binding protein p300 b.	Heat shock protein 90, alpha (cytosolic), class B member 1.	0.477
LOC103468460	snw1	ENSPREP00000026558	ENSPREP00000027074	E1A binding protein p300 b.	SNW domain containing 1.	0.675
LOC103473773	LOC103464091	ENSPREP00000020499	ENSPREP00000000408	Mothers against decapentaplegic homolog.	CREB binding protein a.	0.521
LOC103473773	LOC103468460	ENSPREP00000020499	ENSPREP00000026558	Mothers against decapentaplegic homolog.	E1A binding protein p300 b.	0.592
LOC103473773	LOC103477474	ENSPREP00000020499	ENSPREP00000022544	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC103473773	LOC103482005	ENSPREP00000020499	ENSPREP00000030842	Mothers against decapentaplegic homolog.	E1A binding protein p300 a.	0.592
LOC103473773	crebbp	ENSPREP00000020499	ENSPREP00000011232	Mothers against decapentaplegic homolog.	CREB binding protein b.	0.521
LOC103473773	men1	ENSPREP00000020499	ENSPREP00000005615	Mothers against decapentaplegic homolog.	Multiple endocrine neoplasia I.	0.546