(19 nodes) Otic vesicle formation network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mdn1	Midasin AAA ATPase 1. (3952 aa)
	ENSPREP00000001981	Uncharacterized protein. (359 aa)
	LOC103481447	Paired box 2b. (392 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (236 aa)
	cep290	Centrosomal protein 290. (2041 aa)
	LOC103471035	Mothers against decapentaplegic homolog. (475 aa)
	dlx3	Distal-less homeobox 3b. (281 aa)
	pax5	Paired box 5. (396 aa)
	ENSPREP00000010317	Uncharacterized protein. (390 aa)
	fst	Follistatin a. (351 aa)
	chrd	Chordin; Belongs to the chordin family. (949 aa)
	tcap	Titin-cap (telethonin). (187 aa)
	pax8	Paired box 8. (495 aa)
	ENSPREP00000025214	Paired domain-containing protein. (156 aa)
	ENSPREP00000025759	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
	LOC103476847	Paired box 2a. (322 aa)
	LOC103476999	Homeobox domain-containing protein. (153 aa)
	gata3	GATA binding protein 3. (483 aa)
	LOC103476521	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000001981	mdn1	ENSPREP00000001981	ENSPREP00000001868	Uncharacterized protein.	Midasin AAA ATPase 1.	0.947
LOC103471035	chrd	ENSPREP00000005305	ENSPREP00000014581	Mothers against decapentaplegic homolog.	Chordin; Belongs to the chordin family.	0.482
LOC103476521	chrd	ENSPREP00000029747	ENSPREP00000014581	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Chordin; Belongs to the chordin family.	0.486
LOC103476521	dlx3	ENSPREP00000029747	ENSPREP00000006756	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Distal-less homeobox 3b.	0.404
LOC103476521	fgf3	ENSPREP00000029747	ENSPREP00000002583	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.795
chrd	LOC103471035	ENSPREP00000014581	ENSPREP00000005305	Chordin; Belongs to the chordin family.	Mothers against decapentaplegic homolog.	0.482
chrd	LOC103476521	ENSPREP00000014581	ENSPREP00000029747	Chordin; Belongs to the chordin family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.486
chrd	fst	ENSPREP00000014581	ENSPREP00000014118	Chordin; Belongs to the chordin family.	Follistatin a.	0.643
dlx3	LOC103476521	ENSPREP00000006756	ENSPREP00000029747	Distal-less homeobox 3b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.404
dlx3	gata3	ENSPREP00000006756	ENSPREP00000026693	Distal-less homeobox 3b.	GATA binding protein 3.	0.617
dlx3	pax8	ENSPREP00000006756	ENSPREP00000021891	Distal-less homeobox 3b.	Paired box 8.	0.523
fgf3	LOC103476521	ENSPREP00000002583	ENSPREP00000029747	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.795
fst	chrd	ENSPREP00000014118	ENSPREP00000014581	Follistatin a.	Chordin; Belongs to the chordin family.	0.643
gata3	dlx3	ENSPREP00000026693	ENSPREP00000006756	GATA binding protein 3.	Distal-less homeobox 3b.	0.617
mdn1	ENSPREP00000001981	ENSPREP00000001868	ENSPREP00000001981	Midasin AAA ATPase 1.	Uncharacterized protein.	0.947
pax8	dlx3	ENSPREP00000021891	ENSPREP00000006756	Paired box 8.	Distal-less homeobox 3b.	0.523