(18 nodes) Lipopolysaccharide-mediated signaling pathway network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL18	Uncharacterized protein. (218 aa)
	ENSPREP00000024840	TIR domain-containing protein. (916 aa)
	LOC103478193	Uncharacterized protein. (433 aa)
	LOC103465399	Uncharacterized protein. (486 aa)
	LOC103475119	Transforming growth factor beta; Belongs to the TGF-beta family. (380 aa)
	LOC103457805	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (301 aa)
	Ptafr	Platelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	LOC103480193	SCY domain-containing protein. (93 aa)
	LOC103481249	Interferon regulatory factor 3. (465 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (582 aa)
	LOC103466618	MALT paracaspase 3. (573 aa)
	LOC103469935	MALT paracaspase 1. (828 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (315 aa)
	mtdh	Metadherin a. (519 aa)
	ENSPREP00000018398	MALT paracaspase 2. (715 aa)
	ENSPREP00000018760	Protein kinase domain-containing protein. (507 aa)
	LOC103470686	Interleukin-1. (247 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (490 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000018398	LOC103457805	ENSPREP00000018398	ENSPREP00000027480	MALT paracaspase 2.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	0.421
ENSPREP00000018398	LOC103470686	ENSPREP00000018398	ENSPREP00000019387	MALT paracaspase 2.	Interleukin-1.	0.446
ENSPREP00000018398	nfkbia	ENSPREP00000018398	ENSPREP00000012072	MALT paracaspase 2.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.	0.421
ENSPREP00000018760	ENSPREP00000024840	ENSPREP00000018760	ENSPREP00000024840	Protein kinase domain-containing protein.	TIR domain-containing protein.	0.744
ENSPREP00000018760	LOC103457805	ENSPREP00000018760	ENSPREP00000027480	Protein kinase domain-containing protein.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	0.573
ENSPREP00000018760	LOC103470686	ENSPREP00000018760	ENSPREP00000019387	Protein kinase domain-containing protein.	Interleukin-1.	0.767
ENSPREP00000018760	LOC103481249	ENSPREP00000018760	ENSPREP00000032515	Protein kinase domain-containing protein.	Interferon regulatory factor 3.	0.433
ENSPREP00000018760	nfkbia	ENSPREP00000018760	ENSPREP00000012072	Protein kinase domain-containing protein.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.	0.573
ENSPREP00000018760	ripk2	ENSPREP00000018760	ENSPREP00000009886	Protein kinase domain-containing protein.	Receptor-interacting serine-threonine kinase 2.	0.641
ENSPREP00000024840	ENSPREP00000018760	ENSPREP00000024840	ENSPREP00000018760	TIR domain-containing protein.	Protein kinase domain-containing protein.	0.744
ENSPREP00000024840	IL18	ENSPREP00000024840	ENSPREP00000023832	TIR domain-containing protein.	Uncharacterized protein.	0.475
ENSPREP00000024840	LOC103457805	ENSPREP00000024840	ENSPREP00000027480	TIR domain-containing protein.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	0.432
ENSPREP00000024840	LOC103465399	ENSPREP00000024840	ENSPREP00000025737	TIR domain-containing protein.	Uncharacterized protein.	0.598
ENSPREP00000024840	LOC103470686	ENSPREP00000024840	ENSPREP00000019387	TIR domain-containing protein.	Interleukin-1.	0.660
ENSPREP00000024840	LOC103475119	ENSPREP00000024840	ENSPREP00000027136	TIR domain-containing protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.403
ENSPREP00000024840	LOC103481249	ENSPREP00000024840	ENSPREP00000032515	TIR domain-containing protein.	Interferon regulatory factor 3.	0.738
ENSPREP00000024840	Ptafr	ENSPREP00000024840	ENSPREP00000028569	TIR domain-containing protein.	Platelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family.	0.454
ENSPREP00000024840	nfkbia	ENSPREP00000024840	ENSPREP00000012072	TIR domain-containing protein.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.	0.432
ENSPREP00000024840	ripk2	ENSPREP00000024840	ENSPREP00000009886	TIR domain-containing protein.	Receptor-interacting serine-threonine kinase 2.	0.567
ENSPREP00000024840	scarb1	ENSPREP00000024840	ENSPREP00000021860	TIR domain-containing protein.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.791