(34 nodes) Positive regulation of telomere maintenance network (Poecilia reticulata)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	slx4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1463 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1057 aa)
	dkc1	Dyskeratosis congenita 1, dyskerin. (553 aa)
	LOC103480107	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (263 aa)
	atrx	ATRX chromatin remodeler. (2188 aa)
	cct2	Chaperonin containing TCP1, subunit 2 (beta). (535 aa)
	ino80d	INO80 complex subunit Da. (1025 aa)
	LOC103473565	Poly [ADP-ribose] polymerase. (1285 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1355 aa)
	nek2	NIMA-related kinase 2. (352 aa)
	tfpt	TCF3 (E2A) fusion partner. (199 aa)
	pnkp	Polynucleotide kinase 3'-phosphatase. (593 aa)
	xrcc5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (731 aa)
	ercc1	Excision repair cross-complementation group 1. (358 aa)
	uchl5	Ubiquitin carboxyl-terminal hydrolase. (339 aa)
	atr	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2589 aa)
	ppp1r10	Protein phosphatase 1, regulatory subunit 10. (805 aa)
	terf2	HTH myb-type domain-containing protein. (635 aa)
	ino80e	INO80 complex subunit E. (211 aa)
	ino80	INO80 complex ATPase subunit. (1484 aa)
	cct5	Chaperonin containing TCP1, subunit 5 (epsilon). (541 aa)
	mcrs1	Microspherule protein 1. (474 aa)
	mapkapk5	MAPK activated protein kinase 5. (471 aa)
	cct3	T-complex protein 1 subunit gamma. (540 aa)
	fbxo4	F-box protein 4. (361 aa)
	atm	Non-specific serine/threonine protein kinase. (3091 aa)
	pot1	Telo_bind domain-containing protein. (763 aa)
	LOC103479463	Sirtuin 6. (339 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (418 aa)
	LOC103466742	Uncharacterized protein. (442 aa)
	nfrkb	Nuclear factor related to kappaB binding protein. (1283 aa)
	LOC103469721	Poly [ADP-ribose] polymerase. (1263 aa)
	naf1	Uncharacterized protein. (481 aa)
	map3k4	Mitogen-activated protein kinase kinase kinase 4. (1587 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103466742	dkc1	ENSPREP00000028462	ENSPREP00000005982	Uncharacterized protein.	Dyskeratosis congenita 1, dyskerin.	0.661
LOC103466742	pot1	ENSPREP00000028462	ENSPREP00000024452	Uncharacterized protein.	Telo_bind domain-containing protein.	0.988
LOC103466742	terf2	ENSPREP00000028462	ENSPREP00000018221	Uncharacterized protein.	HTH myb-type domain-containing protein.	0.982
LOC103480107	atm	ENSPREP00000006257	ENSPREP00000024388	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	Non-specific serine/threonine protein kinase.	0.745
LOC103480107	atr	ENSPREP00000006257	ENSPREP00000016955	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.549
LOC103480107	ercc1	ENSPREP00000006257	ENSPREP00000015481	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	Excision repair cross-complementation group 1.	0.858
LOC103480107	rad50	ENSPREP00000006257	ENSPREP00000008829	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	RAD50 homolog, double strand break repair protein.	0.597
LOC103480107	slx4	ENSPREP00000006257	ENSPREP00000000407	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.980
LOC103480107	xrcc5	ENSPREP00000006257	ENSPREP00000014485	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.453
atm	LOC103480107	ENSPREP00000024388	ENSPREP00000006257	Non-specific serine/threonine protein kinase.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.745
atm	atr	ENSPREP00000024388	ENSPREP00000016955	Non-specific serine/threonine protein kinase.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.999
atm	atrx	ENSPREP00000024388	ENSPREP00000006575	Non-specific serine/threonine protein kinase.	ATRX chromatin remodeler.	0.631
atm	ercc1	ENSPREP00000024388	ENSPREP00000015481	Non-specific serine/threonine protein kinase.	Excision repair cross-complementation group 1.	0.675
atm	rad50	ENSPREP00000024388	ENSPREP00000008829	Non-specific serine/threonine protein kinase.	RAD50 homolog, double strand break repair protein.	0.997
atm	slx4	ENSPREP00000024388	ENSPREP00000000407	Non-specific serine/threonine protein kinase.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.728
atm	terf2	ENSPREP00000024388	ENSPREP00000018221	Non-specific serine/threonine protein kinase.	HTH myb-type domain-containing protein.	0.419
atm	uchl5	ENSPREP00000024388	ENSPREP00000015675	Non-specific serine/threonine protein kinase.	Ubiquitin carboxyl-terminal hydrolase.	0.474
atm	xrcc5	ENSPREP00000024388	ENSPREP00000014485	Non-specific serine/threonine protein kinase.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.935
atr	LOC103480107	ENSPREP00000016955	ENSPREP00000006257	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.549
atr	atm	ENSPREP00000016955	ENSPREP00000024388	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Non-specific serine/threonine protein kinase.	0.999