(15 nodes) Filopodium tip network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABI1	Abl-interactor 1a. (577 aa)
	ENSPREP00000003699	SH3 domain-containing protein. (137 aa)
	ENSPREP00000003717	Uncharacterized protein. (76 aa)
	fmr1	Fragile X mental retardation 1. (273 aa)
	myo3b	Myosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1265 aa)
	abitram	Actin binding transcription modulator. (180 aa)
	LOC103468143	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (938 aa)
	ube2k	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
	LOC103461055	Fragile X mental retardation 1. (400 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (195 aa)
	LOC103476913	MORN repeat containing 4. (146 aa)
	LOC103470129	Uncharacterized protein. (145 aa)
	ENSPREP00000032937	SH3 domain-containing protein. (87 aa)
	myo3a	Myosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1787 aa)
	LOC103471315	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (204 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	ENSPREP00000032937	ENSPREP00000001513	ENSPREP00000032937	Abl-interactor 1a.	SH3 domain-containing protein.	0.625
ENSPREP00000003699	ENSPREP00000032937	ENSPREP00000003699	ENSPREP00000032937	SH3 domain-containing protein.	SH3 domain-containing protein.	0.634
ENSPREP00000003717	ENSPREP00000032937	ENSPREP00000003717	ENSPREP00000032937	Uncharacterized protein.	SH3 domain-containing protein.	0.625
ENSPREP00000032937	ABI1	ENSPREP00000032937	ENSPREP00000001513	SH3 domain-containing protein.	Abl-interactor 1a.	0.625
ENSPREP00000032937	ENSPREP00000003699	ENSPREP00000032937	ENSPREP00000003699	SH3 domain-containing protein.	SH3 domain-containing protein.	0.634
ENSPREP00000032937	ENSPREP00000003717	ENSPREP00000032937	ENSPREP00000003717	SH3 domain-containing protein.	Uncharacterized protein.	0.625
LOC103461055	fmr1	ENSPREP00000020915	ENSPREP00000004643	Fragile X mental retardation 1.	Fragile X mental retardation 1.	0.932
fmr1	LOC103461055	ENSPREP00000004643	ENSPREP00000020915	Fragile X mental retardation 1.	Fragile X mental retardation 1.	0.932