STRINGSTRING
chd9 chd9 LOC103481567 LOC103481567 dqx1 dqx1 gins4 gins4 blm blm hfm1 hfm1 pif1 pif1 mcm4 mcm4 rtel1 rtel1 ruvbl2 ruvbl2 dna2 dna2 xrcc5 xrcc5 wrnip1 wrnip1 mcm3 mcm3 fancm fancm MCMDC2 MCMDC2 gtf2f2 gtf2f2 ercc3 ercc3 xrcc6 xrcc6 mcm9 mcm9 mcm6 mcm6 chd8 chd8 chd1l chd1l smarcad1 smarcad1 chtf8 chtf8 ercc2 ercc2 dhx9 dhx9 ENSPREP00000000518 ENSPREP00000000518 rad51 rad51 LOC103472838 LOC103472838 aire aire gins3 gins3 dhx36 dhx36 mcm2 mcm2 chd6 chd6 RPA1 RPA1 LOC103474198 LOC103474198 rfc3 rfc3 twnk twnk chd3 chd3 ighmbp2 ighmbp2 chd4 chd4 cdc45 cdc45 LOC103476760 LOC103476760 ddx1 ddx1 recql4 recql4 ruvbl1 ruvbl1 LOC103476593 LOC103476593 chd1 chd1 helq helq rfc4 rfc4 gins2 gins2 recql recql LOC103461004 LOC103461004 MCM7 MCM7 mcm7 mcm7 chd5 chd5 supv3l1 supv3l1 ENSPREP00000021919 ENSPREP00000021919 ENSPREP00000022010 ENSPREP00000022010 Mcm5 Mcm5 brip1 brip1 recql5 recql5 nbn nbn pot1 pot1 ENSPREP00000026061 ENSPREP00000026061 ascc3 ascc3 ENSPREP00000026167 ENSPREP00000026167 atrx atrx rfc2 rfc2 rfc5 rfc5 ddx11 ddx11 rad50 rad50 ENSPREP00000009478 ENSPREP00000009478 ENSPREP00000009552 ENSPREP00000009552 ENSPREP00000009577 ENSPREP00000009577
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chd9Chromodomain helicase DNA binding protein 9. (3004 aa)
LOC103481567DEAH (Asp-Glu-Ala-His) box polypeptide 32a. (737 aa)
dqx1DEAQ box RNA-dependent ATPase 1. (838 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (224 aa)
blmBLM RecQ like helicase. (1399 aa)
hfm1Helicase for meiosis 1. (1062 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (629 aa)
mcm4DNA helicase; Belongs to the MCM family. (880 aa)
rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1180 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (459 aa)
dna2Uncharacterized protein. (1328 aa)
xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (731 aa)
wrnip1WRN helicase interacting protein 1. (522 aa)
mcm3DNA helicase; Belongs to the MCM family. (814 aa)
fancmUncharacterized protein. (1901 aa)
MCMDC2Minichromosome maintenance domain containing 2. (680 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (312 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
xrcc6X-ray repair complementing defective repair in Chinese hamster cells 6. (655 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (923 aa)
mcm6DNA helicase; Belongs to the MCM family. (825 aa)
chd8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2620 aa)
chd1lChromodomain helicase DNA binding protein 1-like. (867 aa)
smarcad1Uncharacterized protein. (1090 aa)
chtf8CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (134 aa)
ercc2Excision repair cross-complementation group 2. (655 aa)
dhx9DEAH (Asp-Glu-Ala-His) box helicase 9. (1216 aa)
ENSPREP00000000518CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (415 aa)
rad51RAD51 recombinase. (219 aa)
LOC103472838Chromodomain helicase DNA binding protein 4a. (1967 aa)
aireAutoimmune regulator. (496 aa)
gins3GINS complex subunit 3. (211 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1057 aa)
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
chd6Chromodomain helicase DNA binding protein 6. (3390 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (674 aa)
LOC103474198Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (537 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
twnkTwinkle mtDNA helicase. (721 aa)
chd3Chromodomain helicase DNA binding protein 3. (1830 aa)
ighmbp2Immunoglobulin mu DNA binding protein 2. (982 aa)
chd4Uncharacterized protein. (1981 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (573 aa)
LOC103476760DEAH (Asp-Glu-Ala-His) box polypeptide 32b. (738 aa)
ddx1DEAD (Asp-Glu-Ala-Asp) box helicase 1. (740 aa)
recql4RecQ helicase-like 4. (1237 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
LOC103476593Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (792 aa)
chd1Chromodomain helicase DNA binding protein 1. (1751 aa)
helqHelicase, POLQ like. (1019 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
recqlATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (642 aa)
LOC103461004General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (267 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (104 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (541 aa)
chd5Uncharacterized protein. (1804 aa)
supv3l1SUV3-like helicase. (760 aa)
ENSPREP00000021919Chromodomain helicase DNA binding protein 7. (1762 aa)
ENSPREP00000022010Uncharacterized protein. (59 aa)
Mcm5Uncharacterized protein. (58 aa)
brip1BRCA1 interacting protein C-terminal helicase 1. (1386 aa)
recql5RecQ helicase-like 5. (1020 aa)
nbnNibrin. (843 aa)
pot1Telo_bind domain-containing protein. (763 aa)
ENSPREP00000026061Excision repair cross-complementation group 6-like. (1081 aa)
ascc3Activating signal cointegrator 1 complex subunit 3. (2197 aa)
ENSPREP00000026167F-box DNA helicase 1. (875 aa)
atrxATRX chromatin remodeler. (2188 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
ddx11DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (815 aa)
rad50RAD50 homolog, double strand break repair protein. (1355 aa)
ENSPREP00000009478DUF4208 domain-containing protein. (509 aa)
ENSPREP00000009552Uncharacterized protein. (331 aa)
ENSPREP00000009577Uncharacterized protein. (393 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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