(32 nodes) Positive regulation of DNA-templated transcription, elongation network (Poecilia reticulata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	LOC103463288	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (548 aa)
	pwwp2b	PWWP domain containing 2B. (622 aa)
	LOC103475011	Uncharacterized protein. (1473 aa)
	ENSPREP00000001027	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (467 aa)
	thoc5	THO complex 5. (683 aa)
	cdk13	Cyclin-dependent kinase 13. (1409 aa)
	eapp	E2f-associated phosphoprotein. (303 aa)
	Pwwp2a	Uncharacterized protein. (640 aa)
	ENSPREP00000005975	PWWP domain-containing protein. (156 aa)
	LOC103462177	Uncharacterized protein. (662 aa)
	brd4	Bromodomain containing 4. (1560 aa)
	cdc73	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (576 aa)
	LOC103466632	Si:ch211-13k12.2. (602 aa)
	thoc1	THO complex 1. (654 aa)
	supt5h	Transcription elongation factor SPT5. (1059 aa)
	supt4h1	SPT4 homolog, DSIF elongation factor subunit. (174 aa)
	ENSPREP00000012074	CYCLIN domain-containing protein; Belongs to the cyclin family. (177 aa)
	LOC103479150	Zgc:154006. (550 aa)
	supt16h	SPT16 homolog, facilitates chromatin remodeling subunit. (1077 aa)
	ell	Elongation factor RNA polymerase II. (611 aa)
	supt6h	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1825 aa)
	LOC103458470	Uncharacterized protein. (627 aa)
	cdk12	Cyclin-dependent kinase 12. (1352 aa)
	ercc6	Excision repair cross-complementation group 6. (1402 aa)
	LOC103482006	Chromobox homolog 7b. (277 aa)
	ell2	Elongation factor, RNA polymerase II, 2. (670 aa)
	ccnt1	Cyclin T1; Belongs to the cyclin family. (189 aa)
	leo1	LEO1 homolog, Paf1/RNA polymerase II complex component. (631 aa)
	ENSPREP00000026644	Chromo domain-containing protein. (60 aa)
	ccnk	Cyclin K; Belongs to the cyclin family. (541 aa)
	ccnt2	Cyclin T2; Belongs to the cyclin family. (687 aa)
	ENSPREP00000023437	Uncharacterized protein. (97 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000001027	ENSPREP00000012074	ENSPREP00000001027	ENSPREP00000012074	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.687
ENSPREP00000001027	LOC103458470	ENSPREP00000001027	ENSPREP00000014702	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.489
ENSPREP00000001027	LOC103462177	ENSPREP00000001027	ENSPREP00000007478	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.493
ENSPREP00000001027	LOC103466632	ENSPREP00000001027	ENSPREP00000009693	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Si:ch211-13k12.2.	0.493
ENSPREP00000001027	ccnk	ENSPREP00000001027	ENSPREP00000025697	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Cyclin K; Belongs to the cyclin family.	0.745
ENSPREP00000001027	ccnt1	ENSPREP00000001027	ENSPREP00000029009	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Cyclin T1; Belongs to the cyclin family.	0.696
ENSPREP00000001027	ccnt2	ENSPREP00000001027	ENSPREP00000024213	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Cyclin T2; Belongs to the cyclin family.	0.687
ENSPREP00000001027	ell	ENSPREP00000001027	ENSPREP00000013343	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Elongation factor RNA polymerase II.	0.493
ENSPREP00000001027	ell2	ENSPREP00000001027	ENSPREP00000030782	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Elongation factor, RNA polymerase II, 2.	0.493
ENSPREP00000001027	supt16h	ENSPREP00000001027	ENSPREP00000013238	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.715
ENSPREP00000001027	supt4h1	ENSPREP00000001027	ENSPREP00000011803	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	SPT4 homolog, DSIF elongation factor subunit.	0.671
ENSPREP00000001027	supt5h	ENSPREP00000001027	ENSPREP00000009918	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Transcription elongation factor SPT5.	0.765
ENSPREP00000005975	Pwwp2a	ENSPREP00000005975	ENSPREP00000005955	PWWP domain-containing protein.	Uncharacterized protein.	0.900
ENSPREP00000012074	ENSPREP00000001027	ENSPREP00000012074	ENSPREP00000001027	CYCLIN domain-containing protein; Belongs to the cyclin family.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.687
ENSPREP00000012074	LOC103458470	ENSPREP00000012074	ENSPREP00000014702	CYCLIN domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.650
ENSPREP00000012074	LOC103462177	ENSPREP00000012074	ENSPREP00000007478	CYCLIN domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.650
ENSPREP00000012074	LOC103466632	ENSPREP00000012074	ENSPREP00000009693	CYCLIN domain-containing protein; Belongs to the cyclin family.	Si:ch211-13k12.2.	0.650
ENSPREP00000012074	ccnk	ENSPREP00000012074	ENSPREP00000025697	CYCLIN domain-containing protein; Belongs to the cyclin family.	Cyclin K; Belongs to the cyclin family.	0.727
ENSPREP00000012074	ccnt1	ENSPREP00000012074	ENSPREP00000029009	CYCLIN domain-containing protein; Belongs to the cyclin family.	Cyclin T1; Belongs to the cyclin family.	0.631
ENSPREP00000012074	cdc73	ENSPREP00000012074	ENSPREP00000008375	CYCLIN domain-containing protein; Belongs to the cyclin family.	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae).	0.417