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hpgd hpgd elovl5 elovl5 ptges ptges tbxas1 tbxas1 ENSPREP00000030584 ENSPREP00000030584 LOC103475417 LOC103475417 ENSPREP00000029874 ENSPREP00000029874 plaa plaa alox5 alox5 ALOX15B ALOX15B daglb daglb LOC103466718 LOC103466718 LOC103466720 LOC103466720 LOC103475198 LOC103475198 LOC103475118 LOC103475118 LOC103466808 LOC103466808 LOC103466717 LOC103466717 LOC103466716 LOC103466716 elovl7 elovl7 LOC103476842 LOC103476842 LOC103482420 LOC103482420 LOC103471983 LOC103471983 ZADH2 ZADH2 ptgr2 ptgr2 LOC103477396 LOC103477396 LOC103478339 LOC103478339 mgll mgll LOC103457721 LOC103457721 LOC103466509 LOC103466509 LOC103466510 LOC103466510 LOC103466511 LOC103466511 LOC103459460 LOC103459460 tnfrsf1a tnfrsf1a LOC103463586 LOC103463586 LOC103463592 LOC103463592 elovl6 elovl6 LOC103463607 LOC103463607 LOC103465223 LOC103465223 ptgs2 ptgs2 LOC103465828 LOC103465828 edn1 edn1 ENSPREP00000012104 ENSPREP00000012104 ENSPREP00000010558 ENSPREP00000010558 LOC103477226 LOC103477226 LOC103469906 LOC103469906 ENSPREP00000009189 ENSPREP00000009189 LOC103460018 LOC103460018 prxl2b prxl2b ENSPREP00000008146 ENSPREP00000008146 ENSPREP00000008109 ENSPREP00000008109 ENSPREP00000008098 ENSPREP00000008098 LOC103463739 LOC103463739 ENSPREP00000006573 ENSPREP00000006573 LOC103463738 LOC103463738 LOC103461257 LOC103461257 LOC103475975 LOC103475975 LOC103475970 LOC103475970 LOC103463736 LOC103463736 ENSPREP00000005749 ENSPREP00000005749 ptges2 ptges2 ENSPREP00000005565 ENSPREP00000005565 ENSPREP00000005402 ENSPREP00000005402 LOC103464557 LOC103464557 LOC103457519 LOC103457519 ENSPREP00000004689 ENSPREP00000004689 LOC103480141 LOC103480141 LOC103457523 LOC103457523 LOC103477101 LOC103477101 ENSPREP00000004076 ENSPREP00000004076 LOC103479605 LOC103479605 LOC103457522 LOC103457522 ENSPREP00000003955 ENSPREP00000003955 ENSPREP00000003914 ENSPREP00000003914 LOC103472722 LOC103472722 LOC103473446 LOC103473446 LOC103481451 LOC103481451 LOC103459850 LOC103459850 LOC103479188 LOC103479188 dagla dagla LOC103467311 LOC103467311
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hpgd15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (292 aa)
elovl5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (294 aa)
ptgesProstaglandin E synthase. (150 aa)
tbxas1Thromboxane A synthase 1 (platelet); Belongs to the cytochrome P450 family. (524 aa)
ENSPREP00000030584Cytochrome P450, family 1, subfamily C, polypeptide 2. (479 aa)
LOC103475417Zgc:153704; Belongs to the calycin superfamily. Lipocalin family. (182 aa)
ENSPREP00000029874EHN domain-containing protein. (190 aa)
plaaPhospholipase A2-activating protein. (797 aa)
alox5Arachidonate 5-lipoxygenase a. (673 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (627 aa)
daglbDiacylglycerol lipase, beta. (675 aa)
LOC103466718Uncharacterized protein; Belongs to the cytochrome P450 family. (487 aa)
LOC103466720Uncharacterized protein; Belongs to the cytochrome P450 family. (487 aa)
LOC103475198Uncharacterized protein; Belongs to the cytochrome P450 family. (410 aa)
LOC103475118Uncharacterized protein; Belongs to the cytochrome P450 family. (555 aa)
LOC103466808Uncharacterized protein. (132 aa)
LOC103466717Uncharacterized protein; Belongs to the cytochrome P450 family. (480 aa)
LOC103466716Uncharacterized protein; Belongs to the cytochrome P450 family. (489 aa)
elovl7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (294 aa)
LOC103476842Stearoyl-CoA desaturase b; Belongs to the fatty acid desaturase type 1 family. (387 aa)
LOC103482420Prostaglandin D2 synthase b, tandem duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (198 aa)
LOC103471983Endothelin 2. (172 aa)
ZADH2Zinc binding alcohol dehydrogenase domain containing 2. (412 aa)
ptgr2Prostaglandin reductase 2. (347 aa)
LOC103477396Elongation of very long chain fatty acids protein. (283 aa)
LOC103478339Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (320 aa)
mgllMonoglyceride lipase. (345 aa)
LOC103457721Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (304 aa)
LOC103466509Fatty acid desaturase 2. (445 aa)
LOC103466510Fatty acid desaturase 2. (460 aa)
LOC103466511Fatty acid desaturase 2. (445 aa)
LOC103459460Patatin-like phospholipase domain containing 8. (747 aa)
tnfrsf1aTumor necrosis factor receptor superfamily, member 1a. (333 aa)
LOC103463586Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
LOC103463592Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (407 aa)
elovl6Elongation of very long chain fatty acids protein. (312 aa)
LOC103463607Elongation of very long chain fatty acids protein. (248 aa)
LOC103465223Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
ptgs2Prostaglandin-endoperoxide synthase 2b. (615 aa)
LOC103465828PNPLA domain-containing protein. (828 aa)
edn1Endothelin 1. (207 aa)
ENSPREP00000012104Phospholipase A(2). (160 aa)
ENSPREP00000010558Prostaglandin E synthase 3b (cytosolic). (140 aa)
LOC103477226Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (471 aa)
LOC103469906Prostaglandin-endoperoxide synthase 1. (593 aa)
ENSPREP00000009189PLAT domain-containing protein. (138 aa)
LOC103460018Uncharacterized protein. (175 aa)
prxl2bPeroxiredoxin like 2B. (201 aa)
ENSPREP00000008146Uncharacterized protein. (225 aa)
ENSPREP00000008109Uncharacterized protein. (328 aa)
ENSPREP00000008098Uncharacterized protein; Belongs to the cytochrome P450 family. (452 aa)
LOC103463739Uncharacterized protein; Belongs to the cytochrome P450 family. (505 aa)
ENSPREP00000006573Uncharacterized protein. (161 aa)
LOC103463738Uncharacterized protein; Belongs to the cytochrome P450 family. (502 aa)
LOC103461257Uncharacterized protein; Belongs to the cytochrome P450 family. (470 aa)
LOC103475975Prostaglandin reductase 1. (329 aa)
LOC103475970Prostaglandin reductase 1. (307 aa)
LOC103463736Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
ENSPREP00000005749Cytochrome P450, family 2, subfamily AD, polypeptide 2; Belongs to the cytochrome P450 family. (493 aa)
ptges2Prostaglandin E synthase 2-like. (389 aa)
ENSPREP00000005565Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (497 aa)
ENSPREP00000005402Glutathione peroxidase; Belongs to the glutathione peroxidase family. (143 aa)
LOC103464557Prostaglandin I2 (prostacyclin) synthase; Belongs to the cytochrome P450 family. (486 aa)
LOC103457519Uncharacterized protein. (646 aa)
ENSPREP00000004689Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (502 aa)
LOC103480141Arachidonate 12-lipoxygenase. (670 aa)
LOC103457523Si:dkey-17e16.9. (643 aa)
LOC103477101Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (536 aa)
ENSPREP00000004076Lipoxygenase domain-containing protein. (423 aa)
LOC103479605Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (312 aa)
LOC103457522Si:dkey-17e16.9. (633 aa)
ENSPREP00000003955Cytochrome P450, family 2, subfamily N, polypeptide 13. (477 aa)
ENSPREP00000003914Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (507 aa)
LOC103472722Cytochrome P450, family 2, subfamily U, polypeptide 1; Belongs to the cytochrome P450 family. (537 aa)
LOC103473446Prostaglandin-endoperoxide synthase 1. (595 aa)
LOC103481451Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (334 aa)
LOC103459850Zgc:152891. (669 aa)
LOC103479188Elongation of very long chain fatty acids protein. (305 aa)
daglaDiacylglycerol lipase, alpha. (1105 aa)
LOC103467311Prostaglandin E synthase 3a (cytosolic). (172 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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