(4 nodes) Peptidyl-lysine deacetylation network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000025121	Sirtuin 3. (152 aa)
	LOC103466083	Si:dkey-103i16.6. (445 aa)
	sirt4	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (311 aa)
	sirt1	Sirtuin 1. (677 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000025121	sirt1	ENSPREP00000025121	ENSPREP00000003960	Sirtuin 3.	Sirtuin 1.	0.668
ENSPREP00000025121	sirt4	ENSPREP00000025121	ENSPREP00000003147	Sirtuin 3.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.464
LOC103466083	sirt1	ENSPREP00000025749	ENSPREP00000003960	Si:dkey-103i16.6.	Sirtuin 1.	0.654
LOC103466083	sirt4	ENSPREP00000025749	ENSPREP00000003147	Si:dkey-103i16.6.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.550
sirt1	ENSPREP00000025121	ENSPREP00000003960	ENSPREP00000025121	Sirtuin 1.	Sirtuin 3.	0.668
sirt1	LOC103466083	ENSPREP00000003960	ENSPREP00000025749	Sirtuin 1.	Si:dkey-103i16.6.	0.654
sirt1	sirt4	ENSPREP00000003960	ENSPREP00000003147	Sirtuin 1.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.496
sirt4	ENSPREP00000025121	ENSPREP00000003147	ENSPREP00000025121	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Sirtuin 3.	0.464
sirt4	LOC103466083	ENSPREP00000003147	ENSPREP00000025749	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Si:dkey-103i16.6.	0.550
sirt4	sirt1	ENSPREP00000003147	ENSPREP00000003960	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Sirtuin 1.	0.496