(6 nodes) siRNA binding network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dhx9	DEAH (Asp-Glu-Ala-His) box helicase 9. (1216 aa)
	mecp2	Methyl CpG binding protein 2. (982 aa)
	tarbp2	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (345 aa)
	prkra	Protein kinase, interferon-inducible double stranded RNA dependent activator. (301 aa)
	fmr1	Fragile X mental retardation 1. (273 aa)
	LOC103461055	Fragile X mental retardation 1. (400 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103461055	fmr1	ENSPREP00000020915	ENSPREP00000004643	Fragile X mental retardation 1.	Fragile X mental retardation 1.	0.932
LOC103461055	mecp2	ENSPREP00000020915	ENSPREP00000018569	Fragile X mental retardation 1.	Methyl CpG binding protein 2.	0.461
fmr1	LOC103461055	ENSPREP00000004643	ENSPREP00000020915	Fragile X mental retardation 1.	Fragile X mental retardation 1.	0.932
fmr1	mecp2	ENSPREP00000004643	ENSPREP00000018569	Fragile X mental retardation 1.	Methyl CpG binding protein 2.	0.461
mecp2	LOC103461055	ENSPREP00000018569	ENSPREP00000020915	Methyl CpG binding protein 2.	Fragile X mental retardation 1.	0.461
mecp2	fmr1	ENSPREP00000018569	ENSPREP00000004643	Methyl CpG binding protein 2.	Fragile X mental retardation 1.	0.461