(17 nodes) Pattern recognition receptor activity network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103467691	Peptidoglycan recognition protein 2. (489 aa)
	Ptafr	Platelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	tnfaip8l2	Tumor necrosis factor, alpha-induced protein 8-like 2b. (186 aa)
	LOC103457268	Si:ch211-108d22.2. (2793 aa)
	nod2	Nucleotide-binding oligomerization domain containing 2. (996 aa)
	COLEC12	Collectin subfamily member 12. (761 aa)
	LOC103468351	Peptidoglycan recognition protein 6. (477 aa)
	ENSPREP00000018072	Uncharacterized protein. (672 aa)
	nod1	Nucleotide-binding oligomerization domain containing 1. (884 aa)
	ENSPREP00000002598	Uncharacterized protein. (117 aa)
	ENSPREP00000002617	Uncharacterized protein. (98 aa)
	LOC103459167	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1052 aa)
	LOC103468108	C-type lectin domain-containing protein. (185 aa)
	LOC103474747	Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (203 aa)
	LOC103479820	Collectin sub-family member 12. (761 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (490 aa)
	ENSPREP00000024840	TIR domain-containing protein. (916 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002598	ENSPREP00000024840	ENSPREP00000002598	ENSPREP00000024840	Uncharacterized protein.	TIR domain-containing protein.	0.459
ENSPREP00000002617	ENSPREP00000024840	ENSPREP00000002617	ENSPREP00000024840	Uncharacterized protein.	TIR domain-containing protein.	0.459
ENSPREP00000024840	ENSPREP00000002598	ENSPREP00000024840	ENSPREP00000002598	TIR domain-containing protein.	Uncharacterized protein.	0.459
ENSPREP00000024840	ENSPREP00000002617	ENSPREP00000024840	ENSPREP00000002617	TIR domain-containing protein.	Uncharacterized protein.	0.459
ENSPREP00000024840	LOC103459167	ENSPREP00000024840	ENSPREP00000002624	TIR domain-containing protein.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.459
ENSPREP00000024840	Ptafr	ENSPREP00000024840	ENSPREP00000028569	TIR domain-containing protein.	Platelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family.	0.454
ENSPREP00000024840	scarb1	ENSPREP00000024840	ENSPREP00000021860	TIR domain-containing protein.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.791
LOC103459167	ENSPREP00000024840	ENSPREP00000002624	ENSPREP00000024840	Toll-like receptor 7; Belongs to the Toll-like receptor family.	TIR domain-containing protein.	0.459
LOC103467691	LOC103474747	ENSPREP00000026832	ENSPREP00000006046	Peptidoglycan recognition protein 2.	Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.	0.443
LOC103474747	LOC103467691	ENSPREP00000006046	ENSPREP00000026832	Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.	Peptidoglycan recognition protein 2.	0.443
Ptafr	ENSPREP00000024840	ENSPREP00000028569	ENSPREP00000024840	Platelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family.	TIR domain-containing protein.	0.454
scarb1	ENSPREP00000024840	ENSPREP00000021860	ENSPREP00000024840	Scavenger receptor class B, member 1; Belongs to the CD36 family.	TIR domain-containing protein.	0.791