(9 nodes) TORC1 signaling network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000016378	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (702 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1350 aa)
	ENSPREP00000010666	Uncharacterized protein. (64 aa)
	ENSPREP00000011155	Uncharacterized protein. (74 aa)
	Nprl3	NPR3-like, GATOR1 complex subunit. (206 aa)
	Mtor	Serine/threonine-protein kinase TOR. (1001 aa)
	ENSPREP00000027430	CARD domain-containing protein. (524 aa)
	LOC103468544	Guanylate kinase-like domain-containing protein. (308 aa)
	clec16a	C-type lectin domain containing 16A. (1122 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000010666	ENSPREP00000016378	ENSPREP00000010666	ENSPREP00000016378	Uncharacterized protein.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.557
ENSPREP00000010666	Mtor	ENSPREP00000010666	ENSPREP00000016474	Uncharacterized protein.	Serine/threonine-protein kinase TOR.	0.557
ENSPREP00000010666	rptor	ENSPREP00000010666	ENSPREP00000004520	Uncharacterized protein.	Regulatory associated protein of MTOR, complex 1.	0.633
ENSPREP00000011155	ENSPREP00000016378	ENSPREP00000011155	ENSPREP00000016378	Uncharacterized protein.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.557
ENSPREP00000011155	Mtor	ENSPREP00000011155	ENSPREP00000016474	Uncharacterized protein.	Serine/threonine-protein kinase TOR.	0.557
ENSPREP00000011155	rptor	ENSPREP00000011155	ENSPREP00000004520	Uncharacterized protein.	Regulatory associated protein of MTOR, complex 1.	0.633
ENSPREP00000016378	ENSPREP00000010666	ENSPREP00000016378	ENSPREP00000010666	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.557
ENSPREP00000016378	ENSPREP00000011155	ENSPREP00000016378	ENSPREP00000011155	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.557
ENSPREP00000016378	Mtor	ENSPREP00000016378	ENSPREP00000016474	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase TOR.	0.934
ENSPREP00000016378	Nprl3	ENSPREP00000016378	ENSPREP00000011200	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	NPR3-like, GATOR1 complex subunit.	0.557
ENSPREP00000016378	rptor	ENSPREP00000016378	ENSPREP00000004520	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Regulatory associated protein of MTOR, complex 1.	0.987
ENSPREP00000027430	LOC103468544	ENSPREP00000027430	ENSPREP00000027446	CARD domain-containing protein.	Guanylate kinase-like domain-containing protein.	0.900
LOC103468544	ENSPREP00000027430	ENSPREP00000027446	ENSPREP00000027430	Guanylate kinase-like domain-containing protein.	CARD domain-containing protein.	0.900
Mtor	ENSPREP00000010666	ENSPREP00000016474	ENSPREP00000010666	Serine/threonine-protein kinase TOR.	Uncharacterized protein.	0.557
Mtor	ENSPREP00000011155	ENSPREP00000016474	ENSPREP00000011155	Serine/threonine-protein kinase TOR.	Uncharacterized protein.	0.557
Mtor	ENSPREP00000016378	ENSPREP00000016474	ENSPREP00000016378	Serine/threonine-protein kinase TOR.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.934
Mtor	Nprl3	ENSPREP00000016474	ENSPREP00000011200	Serine/threonine-protein kinase TOR.	NPR3-like, GATOR1 complex subunit.	0.557
Mtor	rptor	ENSPREP00000016474	ENSPREP00000004520	Serine/threonine-protein kinase TOR.	Regulatory associated protein of MTOR, complex 1.	0.998
Nprl3	ENSPREP00000016378	ENSPREP00000011200	ENSPREP00000016378	NPR3-like, GATOR1 complex subunit.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.557
Nprl3	Mtor	ENSPREP00000011200	ENSPREP00000016474	NPR3-like, GATOR1 complex subunit.	Serine/threonine-protein kinase TOR.	0.557