STRINGSTRING
LOC103459381 LOC103459381 coq6 coq6 ubiad1 ubiad1 tdo2 tdo2 ENSPREP00000014657 ENSPREP00000014657 LOC103469397 LOC103469397 LOC103470503 LOC103470503 LOC103460103 LOC103460103 coq2 coq2 LOC103474848 LOC103474848 LOC103477241 LOC103477241 vkorc1l1 vkorc1l1 HAGHL HAGHL park7 park7 glod4 glod4 LOC103481412 LOC103481412 coq10a coq10a LOC103470946 LOC103470946 kynu kynu kyat1 kyat1 hsd17b10 hsd17b10 ndufa9 ndufa9 LOC103476526 LOC103476526 LOC103457824 LOC103457824 LOC103457823 LOC103457823 LOC103479463 LOC103479463 srd5a1 srd5a1 LOC103458335 LOC103458335 hsd17b3 hsd17b3 coq3 coq3 coq4 coq4 LOC103480951 LOC103480951 got2 got2 LOC103460857 LOC103460857 kyat3 kyat3 coq8a coq8a aifm2 aifm2 ENSPREP00000018018 ENSPREP00000018018 Tpi1 Tpi1 LOC103476765 LOC103476765 gatd1 gatd1 aldh8a1 aldh8a1 kdsr kdsr GLO1 GLO1 aadat aadat coq9 coq9 kmo kmo LOC103459074 LOC103459074 LOC103478941 LOC103478941 LOC103478929 LOC103478929 ENSPREP00000002178 ENSPREP00000002178 LOC103472835 LOC103472835 LOC103459403 LOC103459403 LOC103459390 LOC103459390 cryzl1 cryzl1 pdss1 pdss1 coq7 coq7 afmid afmid pdss2 pdss2 ENSPREP00000008295 ENSPREP00000008295 LOC103471931 LOC103471931 coq5 coq5 LOC103476570 LOC103476570 hagh hagh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103459381Flavodoxin_2 domain-containing protein. (264 aa)
coq6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (482 aa)
ubiad1UbiA prenyltransferase domain containing 1. (350 aa)
tdo2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (403 aa)
ENSPREP00000014657VOC domain-containing protein. (40 aa)
LOC103469397Si:ch73-141c7.1. (244 aa)
LOC103470503Indoleamine 2,3-dioxygenase 1. (422 aa)
LOC103460103NAD(P)H dehydrogenase, quinone 1. (255 aa)
coq24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (380 aa)
LOC103474848Coenzyme Q8B. (649 aa)
LOC1034772413-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (252 aa)
vkorc1l1Vitamin K epoxide reductase complex, subunit 1-like 1. (175 aa)
HAGHLHydroxyacylglutathione hydrolase like. (290 aa)
park7Parkinson protein 7. (189 aa)
glod4Glyoxalase domain containing 4. (211 aa)
LOC103481412Vitamin K epoxide reductase complex, subunit 1. (167 aa)
coq10aCoenzyme Q10A. (249 aa)
LOC103470946G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (423 aa)
kynuKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (463 aa)
kyat1Kynurenine aminotransferase 1. (459 aa)
hsd17b10Hydroxysteroid (17-beta) dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
ndufa9NADH:ubiquinone oxidoreductase subunit A9a. (382 aa)
LOC103476526Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (514 aa)
LOC103457824Uncharacterized protein. (507 aa)
LOC103457823Uncharacterized protein. (511 aa)
LOC103479463Sirtuin 6. (339 aa)
srd5a13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (265 aa)
LOC103458335Coenzyme Q8A, genome duplicate b. (587 aa)
hsd17b3Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)
coq3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (324 aa)
coq4Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (247 aa)
LOC103480951Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (552 aa)
got2Aspartate aminotransferase. (393 aa)
LOC103460857PNKD metallo-beta-lactamase domain containing. (360 aa)
kyat3Kynurenine aminotransferase 3. (459 aa)
coq8aCoenzyme Q8A, genome duplicate a. (674 aa)
aifm2Apoptosis inducing factor mitochondria associated 2. (360 aa)
ENSPREP00000018018Uncharacterized protein. (116 aa)
Tpi1Triosephosphate isomerase. (312 aa)
LOC103476765Uncharacterized protein. (409 aa)
gatd1Glutamine amidotransferase like class 1 domain containing 1. (193 aa)
aldh8a1Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. (490 aa)
kdsr3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (359 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (201 aa)
aadatAminoadipate aminotransferase. (437 aa)
coq9Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (339 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (480 aa)
LOC103459074Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (424 aa)
LOC103478941Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (467 aa)
LOC103478929Si:ch73-71c20.5. (138 aa)
ENSPREP00000002178Uncharacterized protein. (170 aa)
LOC103472835Triosephosphate isomerase. (248 aa)
LOC103459403Flavodoxin_2 domain-containing protein. (262 aa)
LOC103459390Flavodoxin_2 domain-containing protein. (243 aa)
cryzl1Crystallin, zeta (quinone reductase)-like 1. (352 aa)
pdss1Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. (420 aa)
coq75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (221 aa)
afmidKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (292 aa)
pdss2Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (379 aa)
ENSPREP00000008295Uncharacterized protein. (178 aa)
LOC1034719313-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (251 aa)
coq52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (337 aa)
LOC103476570Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (400 aa)
haghHydroxyacylglutathione hydrolase. (309 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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