51 items (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103481795	Nerve growth factor receptor b. (354 aa)
	phex	Phosphate regulating endopeptidase homolog, X-linked. (690 aa)
	ankrd11	Ankyrin repeat domain 11. (2822 aa)
	LOC103470093	Homeobox domain-containing protein. (363 aa)
	ENSPREP00000031054	RELT TNF receptor. (358 aa)
	sostdc1	Sclerostin domain containing 1a. (219 aa)
	tnfsf11	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (268 aa)
	itgb6	Integrin beta; Belongs to the integrin beta chain family. (780 aa)
	nkx2-3	NK2 homeobox 3. (349 aa)
	fam20a	FAM20A golgi associated secretory pathway pseudokinase. (536 aa)
	LOC103458857	Inhibitor of DNA binding 3. (116 aa)
	tspear	LAM_G_DOMAIN domain-containing protein. (652 aa)
	LOC103475119	Transforming growth factor beta; Belongs to the TGF-beta family. (380 aa)
	LOC103467514	Ssu-2 homolog, related sequence 1. (389 aa)
	LOC103480607	Cytochrome P450, family 26, subfamily b, polypeptide 1; Belongs to the cytochrome P450 family. (512 aa)
	LOC103467541	Colony stimulating factor 1b (macrophage). (266 aa)
	nectin1	Nectin cell adhesion molecule 1b. (508 aa)
	LOC103460520	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (434 aa)
	LOC103461155	Neurofibromin 2a (merlin). (394 aa)
	ENSPREP00000023116	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (142 aa)
	wnt6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
	LOC103481136	FAM20C golgi associated secretory pathway kinase. (526 aa)
	ENSPREP00000022877	Uncharacterized protein. (62 aa)
	LOC103464793	Uncharacterized protein. (355 aa)
	HAND1	Heart and neural crest derivatives expressed 1. (212 aa)
	prkci	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (557 aa)
	pam	Peptidylglycine alpha-amidating monooxygenase. (947 aa)
	ENSPREP00000018776	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (824 aa)
	ENSPREP00000018426	Uncharacterized protein. (108 aa)
	rogdi	Rogdi atypical leucine zipper. (290 aa)
	pitx2	Homeobox protein. (312 aa)
	ENSPREP00000014516	Ssu-2 homolog, tandem duplicate 1. (154 aa)
	ngfr	Nerve growth factor receptor a (TNFR superfamily, member 16). (313 aa)
	nf2	Neurofibromin 2b (merlin). (615 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa)
	BAX	BCL2 associated X, apoptosis regulator. (191 aa)
	LOC103462620	Uncharacterized protein. (254 aa)
	ENSPREP00000010780	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (176 aa)
	aqp1	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (268 aa)
	LOC103458736	Thrombospondin-type laminin G domain and EAR repeats a. (701 aa)
	LOC103469251	FAM20C golgi associated secretory pathway kinase a. (569 aa)
	eda	Ectodysplasin A; Belongs to the tumor necrosis factor family. (369 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (865 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)
	LOC103480133	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (390 aa)
	ENSPREP00000004603	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (62 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (719 aa)
	lef1	Lymphoid enhancer-binding factor 1. (422 aa)
	Bcl2l11	Uncharacterized protein. (202 aa)
	LOC103462291	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
	msx1	Muscle segment homeobox 1a. (281 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	Bcl2l11	ENSPREP00000013021	ENSPREP00000002893	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.990
Bcl2l11	BAX	ENSPREP00000002893	ENSPREP00000013021	Uncharacterized protein.	BCL2 associated X, apoptosis regulator.	0.990
CDH2	LOC103469251	ENSPREP00000007079	ENSPREP00000007793	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	FAM20C golgi associated secretory pathway kinase a.	0.404
ENSPREP00000018776	LOC103469251	ENSPREP00000018776	ENSPREP00000007793	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	FAM20C golgi associated secretory pathway kinase a.	0.404
ENSPREP00000023116	wnt6	ENSPREP00000023116	ENSPREP00000023102	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.512
LOC103460520	wnt6	ENSPREP00000023200	ENSPREP00000023102	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.520
LOC103461155	nf2	ENSPREP00000023162	ENSPREP00000014172	Neurofibromin 2a (merlin).	Neurofibromin 2b (merlin).	0.901
LOC103462291	LOC103481795	ENSPREP00000002555	ENSPREP00000033927	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Nerve growth factor receptor b.	0.660
LOC103462620	shh	ENSPREP00000012147	ENSPREP00000013208	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.831
LOC103462620	smo	ENSPREP00000012147	ENSPREP00000005932	Uncharacterized protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.542
LOC103467541	LOC103469251	ENSPREP00000023788	ENSPREP00000007793	Colony stimulating factor 1b (macrophage).	FAM20C golgi associated secretory pathway kinase a.	0.608
LOC103467541	LOC103475119	ENSPREP00000023788	ENSPREP00000027136	Colony stimulating factor 1b (macrophage).	Transforming growth factor beta; Belongs to the TGF-beta family.	0.458
LOC103467541	tnfsf11	ENSPREP00000023788	ENSPREP00000030013	Colony stimulating factor 1b (macrophage).	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.560
LOC103469251	CDH2	ENSPREP00000007793	ENSPREP00000007079	FAM20C golgi associated secretory pathway kinase a.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.404
LOC103469251	ENSPREP00000018776	ENSPREP00000007793	ENSPREP00000018776	FAM20C golgi associated secretory pathway kinase a.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.404
LOC103469251	LOC103467541	ENSPREP00000007793	ENSPREP00000023788	FAM20C golgi associated secretory pathway kinase a.	Colony stimulating factor 1b (macrophage).	0.608
LOC103469251	fam20a	ENSPREP00000007793	ENSPREP00000028945	FAM20C golgi associated secretory pathway kinase a.	FAM20A golgi associated secretory pathway pseudokinase.	0.973
LOC103469251	phex	ENSPREP00000007793	ENSPREP00000033825	FAM20C golgi associated secretory pathway kinase a.	Phosphate regulating endopeptidase homolog, X-linked.	0.549
LOC103475119	LOC103467541	ENSPREP00000027136	ENSPREP00000023788	Transforming growth factor beta; Belongs to the TGF-beta family.	Colony stimulating factor 1b (macrophage).	0.458
LOC103475119	LOC103480133	ENSPREP00000027136	ENSPREP00000004625	Transforming growth factor beta; Belongs to the TGF-beta family.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	0.458