STRINGSTRING
usp16 usp16 LOC103481937 LOC103481937 LOC103464672 LOC103464672 LOC103464456 LOC103464456 Mettl12 Mettl12 wdr92 wdr92 otub1 otub1 ADRM1 ADRM1 UBAP1L UBAP1L ascc2 ascc2 tollip tollip stam2 stam2 ubxn7 ubxn7 aup1 aup1 hgs hgs nsfl1c nsfl1c ILRUN ILRUN ENSPREP00000007989 ENSPREP00000007989 TOM1L2 TOM1L2 uchl3 uchl3 fbxo7 fbxo7 bub3 bub3 armc9 armc9 vps28 vps28 LOC103460775 LOC103460775 tnfaip3 tnfaip3 rnf8 rnf8 ENSPREP00000013515 ENSPREP00000013515 rbck1 rbck1 sharpin sharpin sqstm1 sqstm1 LOC103463560 LOC103463560 nbr1 nbr1 usp5 usp5 Rad23a Rad23a ilrun ilrun ENSPREP00000020277 ENSPREP00000020277 uchl1 uchl1 stam stam LOC103466462 LOC103466462 cuedc1 cuedc1 OTUB2 OTUB2 vps36 vps36 LOC103482437 LOC103482437 usp13 usp13 ENSPREP00000023014 ENSPREP00000023014 Tab3 Tab3 trim32 trim32 rae1 rae1 gga3 gga3 ubr5 ubr5 ubxn2a ubxn2a GGA1 GGA1 RAD23B RAD23B CKS2 CKS2 sprtn sprtn cuedc2 cuedc2 smarcad1 smarcad1 tp53inp2 tp53inp2 faf1 faf1 n4bp1 n4bp1 LOC103466144 LOC103466144 faf2 faf2 tsg101 tsg101 cks1b cks1b tepsin tepsin plaa plaa LOC103466155 LOC103466155 Adrm1 Adrm1 tab2 tab2 marchf7 marchf7 LOC103470250 LOC103470250 ubap1 ubap1 ENSPREP00000031399 ENSPREP00000031399 ubxn10 ubxn10 Wdr48 Wdr48 wdr48 wdr48 mdm2 mdm2 rnf31 rnf31
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
usp16Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. (835 aa)
LOC103481937Uncharacterized protein. (617 aa)
LOC103464672Uncharacterized protein. (647 aa)
LOC103464456Uncharacterized protein; Belongs to the TOM1 family. (497 aa)
Mettl12Methyltranfer_dom domain-containing protein. (221 aa)
wdr92WD repeat domain 92. (358 aa)
otub1Ubiquitin thioesterase. (266 aa)
ADRM1Adhesion regulating molecule 1. (436 aa)
UBAP1LUbiquitin associated protein 1 like. (409 aa)
ascc2Activating signal cointegrator 1 complex subunit 2. (761 aa)
tollipToll interacting protein. (275 aa)
stam2Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2. (516 aa)
ubxn7UBX domain protein 7. (564 aa)
aup1AUP1 lipid droplet regulating VLDL assembly factor. (415 aa)
hgsHepatocyte growth factor-regulated tyrosine kinase substrate. (765 aa)
nsfl1cNSFL1 (p97) cofactor (p47). (374 aa)
ILRUNN_BRCA1_IG domain-containing protein. (322 aa)
ENSPREP00000007989RanBP2-type domain-containing protein. (137 aa)
TOM1L2Target of myb1 like 2 membrane trafficking protein. (588 aa)
uchl3Ubiquitin carboxyl-terminal hydrolase. (233 aa)
fbxo7F-box protein 7. (465 aa)
bub3BUB3 mitotic checkpoint protein. (326 aa)
armc9Armadillo repeat containing 9. (837 aa)
vps28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (210 aa)
LOC103460775Si:dkey-181m9.8. (732 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (799 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (490 aa)
ENSPREP00000013515SEP domain-containing protein. (323 aa)
rbck1RanBP-type and C3HC4-type zinc finger containing 1. (506 aa)
sharpinSHANK-associated RH domain interacting protein. (436 aa)
sqstm1Sequestosome 1. (500 aa)
LOC103463560Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
nbr1NBR1 autophagy cargo receptor a. (1070 aa)
usp5Ubiquitin carboxyl-terminal hydrolase. (848 aa)
Rad23aUbiquitin-like domain-containing protein. (168 aa)
ilrunInflammation and lipid regulator with UBA-like and NBR1-like domains. (283 aa)
ENSPREP00000020277RBR-type E3 ubiquitin transferase. (158 aa)
uchl1Ubiquitin carboxyl-terminal hydrolase. (240 aa)
stamSignal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (512 aa)
LOC103466462UMA domain-containing protein. (378 aa)
cuedc1CUE domain containing 1b. (390 aa)
OTUB2OTU deubiquitinase, ubiquitin aldehyde binding 2. (227 aa)
vps36Vacuolar protein sorting 36 homolog. (382 aa)
LOC103482437Sharpin and rbck1 related. (698 aa)
usp13Ubiquitinyl hydrolase 1. (867 aa)
ENSPREP00000023014VHS domain-containing protein. (140 aa)
Tab3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (561 aa)
trim32Tripartite motif containing 32. (628 aa)
rae1Ribonucleic acid export 1. (369 aa)
gga3Golgi associated, gamma adaptin ear containing, ARF binding protein 3a. (742 aa)
ubr5Ubiquitin protein ligase E3 component n-recognin 5. (2851 aa)
ubxn2aUBX domain protein 2A. (235 aa)
GGA1Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (642 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (421 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
sprtnSprT-like N-terminal domain. (494 aa)
cuedc2CUE domain containing 2. (263 aa)
smarcad1Uncharacterized protein. (1090 aa)
tp53inp2Uncharacterized protein. (287 aa)
faf1Fas (TNFRSF6) associated factor 1. (690 aa)
n4bp1Nedd4 binding protein 1. (818 aa)
LOC103466144Zgc:123278. (130 aa)
faf2Fas associated factor family member 2. (445 aa)
tsg101Tumor susceptibility 101a. (390 aa)
cks1bCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa)
tepsinTEPSIN adaptor related protein complex 4 accessory protein. (612 aa)
plaaPhospholipase A2-activating protein. (797 aa)
LOC103466155UEV domain-containing protein. (471 aa)
Adrm1Adhesion regulating molecule 1. (183 aa)
tab2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (742 aa)
marchf7Membrane-associated ring finger (C3HC4) 7. (779 aa)
LOC103470250Uncharacterized protein. (460 aa)
ubap1Ubiquitin associated protein 1. (455 aa)
ENSPREP00000031399Ring finger protein 168. (425 aa)
ubxn10UBX domain protein 10. (232 aa)
Wdr48WD_REPEATS_REGION domain-containing protein. (163 aa)
wdr48WD repeat domain 48b. (338 aa)
mdm2MDM2 proto-oncogene. (434 aa)
rnf31Ring finger protein 31. (1109 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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