(70 nodes) Negative regulation of neuron apoptotic process network (Poecilia reticulata)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	pink1	PTEN induced kinase 1. (575 aa)
	ENSPREP00000001630	RHD domain-containing protein. (238 aa)
	Nfatc4	Uncharacterized protein. (238 aa)
	LOC103467753	CCAAT enhancer binding protein beta. (285 aa)
	dnajc5b	DnaJ heat shock protein family (Hsp40) member C5 beta. (197 aa)
	LOC103464942	V-set and transmembrane domain containing 2 like. (209 aa)
	btg1	B-cell translocation gene 1, anti-proliferative. (148 aa)
	ENSPREP00000002835	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (282 aa)
	LOC103467735	DnaJ (Hsp40) homolog, subfamily C, member 5aa. (199 aa)
	LOC103472251	Uncharacterized protein. (260 aa)
	unc5b	Unc-5 netrin receptor B. (929 aa)
	psenen	Uncharacterized protein. (66 aa)
	adnp	Activity-dependent neuroprotector homeobox b. (1057 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1049 aa)
	ENSPREP00000007409	NGF domain-containing protein; Belongs to the NGF-beta family. (273 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (937 aa)
	nrbp2	Nuclear receptor binding protein 2b. (482 aa)
	cited1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (143 aa)
	ptprz1	Protein tyrosine phosphatase receptor type Z1a. (1888 aa)
	lig4	DNA ligase. (908 aa)
	ENSPREP00000011364	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1074 aa)
	LOC103468695	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	LOC103476180	Homeobox protein engrailed-like. (284 aa)
	ENSPREP00000012772	GRANULINS domain-containing protein. (152 aa)
	Grn	Uncharacterized protein. (68 aa)
	BAX	BCL2 associated X, apoptosis regulator. (191 aa)
	LOC103463628	Cytokine receptor-like factor 1b. (402 aa)
	foxq1	Forkhead box Q1b. (267 aa)
	ENSPREP00000014929	Wolfram syndrome 1a (wolframin). (784 aa)
	ppt1	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (388 aa)
	LOC103479650	Forkhead box Q1a. (248 aa)
	crlf1	Cytokine receptor-like factor 1a. (400 aa)
	yju2	YJU2 splicing factor homolog. (344 aa)
	xrcc2	X-ray repair cross complementing 2. (292 aa)
	VSTM2L	V-set and transmembrane domain containing 2 like. (248 aa)
	LOC103468998	Uncharacterized protein. (812 aa)
	alkbh1	AlkB homolog 1, histone H2A dioxygenase. (380 aa)
	il6st	Uncharacterized protein. (896 aa)
	mecp2	Methyl CpG binding protein 2. (982 aa)
	ENSPREP00000018595	Uncharacterized protein. (128 aa)
	HDGF	PWWP domain-containing protein. (101 aa)
	ENSPREP00000019402	Protein kinase domain-containing protein. (201 aa)
	gclm	Glutamate-cysteine ligase, modifier subunit. (281 aa)
	ENSPREP00000020034	JunE proto-oncogene, AP-1 transcription factor subunit. (310 aa)
	gdnf	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (229 aa)
	ENSPREP00000020277	RBR-type E3 ubiquitin transferase. (158 aa)
	LOC103461010	Uncharacterized protein. (283 aa)
	Zpr1	ZPR1 zinc finger. (446 aa)
	LOC103459662	Protein tyrosine phosphatase receptor type Z1b. (1436 aa)
	LOC103482469	Homeobox protein engrailed-like. (283 aa)
	ntf3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (304 aa)
	map2k4	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (418 aa)
	dnajc5g	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a. (177 aa)
	ndnf	Neuron-derived neurotrophic factor. (571 aa)
	wfs1	Wolfram syndrome 1b (wolframin). (969 aa)
	LOC103473499	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (435 aa)
	lgmn	Legumain. (437 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1284 aa)
	sncb	Synuclein, beta; Belongs to the synuclein family. (127 aa)
	LOC103470867	Cytoplasmic polyadenylation element binding protein 4a. (741 aa)
	LOC103467432	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (286 aa)
	LOC103481969	Baculoviral IAP repeat containing 5a. (157 aa)
	LOC103461905	DnaJ (Hsp40) homolog, subfamily C, member 5ab. (196 aa)
	vps54	VPS54 subunit of GARP complex. (1027 aa)
	retreg1	Reticulophagy regulator 1. (336 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (1210 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	LOC103458337	J domain-containing protein. (181 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	ENSPREP00000032783	Uncharacterized protein. (313 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000001630	Nfatc4	ENSPREP00000001630	ENSPREP00000001665	RHD domain-containing protein.	Uncharacterized protein.	0.865
ENSPREP00000002835	LOC103467753	ENSPREP00000002835	ENSPREP00000001687	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	CCAAT enhancer binding protein beta.	0.511
ENSPREP00000002835	gdnf	ENSPREP00000002835	ENSPREP00000020036	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.475
ENSPREP00000007409	LOC103467432	ENSPREP00000007409	ENSPREP00000029097	NGF domain-containing protein; Belongs to the NGF-beta family.	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	0.905
ENSPREP00000007409	gdnf	ENSPREP00000007409	ENSPREP00000020036	NGF domain-containing protein; Belongs to the NGF-beta family.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.436
ENSPREP00000019402	map2k4	ENSPREP00000019402	ENSPREP00000026466	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.	0.901
ENSPREP00000020034	LOC103467753	ENSPREP00000020034	ENSPREP00000001687	JunE proto-oncogene, AP-1 transcription factor subunit.	CCAAT enhancer binding protein beta.	0.511
ENSPREP00000020034	gdnf	ENSPREP00000020034	ENSPREP00000020036	JunE proto-oncogene, AP-1 transcription factor subunit.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.475
ENSPREP00000020277	ambra1	ENSPREP00000020277	ENSPREP00000030525	RBR-type E3 ubiquitin transferase.	Autophagy/beclin-1 regulator 1b.	0.601
ENSPREP00000020277	pink1	ENSPREP00000020277	ENSPREP00000032869	RBR-type E3 ubiquitin transferase.	PTEN induced kinase 1.	0.996
ENSPREP00000032783	gdnf	ENSPREP00000032783	ENSPREP00000020036	Uncharacterized protein.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.828
LOC103467432	ENSPREP00000007409	ENSPREP00000029097	ENSPREP00000007409	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	NGF domain-containing protein; Belongs to the NGF-beta family.	0.905
LOC103467432	gdnf	ENSPREP00000029097	ENSPREP00000020036	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	0.436
LOC103467753	ENSPREP00000002835	ENSPREP00000001687	ENSPREP00000002835	CCAAT enhancer binding protein beta.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.511
LOC103467753	ENSPREP00000020034	ENSPREP00000001687	ENSPREP00000020034	CCAAT enhancer binding protein beta.	JunE proto-oncogene, AP-1 transcription factor subunit.	0.511
LOC103467753	ppargc1a	ENSPREP00000001687	ENSPREP00000028362	CCAAT enhancer binding protein beta.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.603
Nfatc4	ENSPREP00000001630	ENSPREP00000001665	ENSPREP00000001630	Uncharacterized protein.	RHD domain-containing protein.	0.865
ambra1	ENSPREP00000020277	ENSPREP00000030525	ENSPREP00000020277	Autophagy/beclin-1 regulator 1b.	RBR-type E3 ubiquitin transferase.	0.601
cln8	ppt1	ENSPREP00000032780	ENSPREP00000014938	CLN8 transmembrane ER and ERGIC protein.	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).	0.622
gclc	gclm	ENSPREP00000032692	ENSPREP00000019849	Glutamate-cysteine ligase, catalytic subunit.	Glutamate-cysteine ligase, modifier subunit.	0.996