STRINGSTRING
lsm6 lsm6 pelo pelo patl2 patl2 LOC103464337 LOC103464337 LOC103459168 LOC103459168 pde12 pde12 Pde9a Pde9a LOC103470954 LOC103470954 LOC103458579 LOC103458579 mettl16 mettl16 kynu kynu UPF2 UPF2 polr2d polr2d rexo4 rexo4 sarm1 sarm1 NT5M NT5M pde5a pde5a ncbp2 ncbp2 edc4 edc4 LOC103474518 LOC103474518 LOC103474517 LOC103474517 xrn1 xrn1 LOC103470073 LOC103470073 Ttc38 Ttc38 RIDA RIDA POP1 POP1 LOC103465496 LOC103465496 LOC103466190 LOC103466190 LOC103478615 LOC103478615 ada ada Fitm2 Fitm2 ENSPREP00000030212 ENSPREP00000030212 LOC103481179 LOC103481179 apobec2 apobec2 LOC103458523 LOC103458523 pde7a pde7a mlycd mlycd LOC103472139 LOC103472139 pan3 pan3 exosc6 exosc6 ythdf2 ythdf2 LOC103473309 LOC103473309 dmgdh dmgdh blvrb blvrb smg7 smg7 pde8a pde8a LOC103476883 LOC103476883 nudt12 nudt12 cnot1 cnot1 pde8b pde8b samd4a samd4a ENSPREP00000027416 ENSPREP00000027416 LOC103467467 LOC103467467 smpdl3a smpdl3a LOC103467464 LOC103467464 tet3 tet3 LOC103471741 LOC103471741 cnot10 cnot10 LOC103477584 LOC103477584 ENSPREP00000026599 ENSPREP00000026599 LOC103466095 LOC103466095 pde4d pde4d smg5 smg5 exosc5 exosc5 fen1 fen1 ENSPREP00000026167 ENSPREP00000026167 ascc3 ascc3 dera dera rbm8a rbm8a nudt18 nudt18 rc3h1 rc3h1 LOC103475092 LOC103475092 ctif ctif acot7 acot7 ENSPREP00000025150 ENSPREP00000025150 LOC103463924 LOC103463924 LOC103459710 LOC103459710 lsm7 lsm7 polr2g polr2g LOC103472033 LOC103472033 lsm2 lsm2 upb1 upb1 atm atm exosc10 exosc10 acmsd acmsd endog endog adal adal edc3 edc3 LOC103481886 LOC103481886 mus81 mus81 LOC103457893 LOC103457893 LOC103457894 LOC103457894 nudt5 nudt5 rnaseh2c rnaseh2c nudt7 nudt7 nudt9 nudt9 rnaseh2a rnaseh2a allc allc LOC103468389 LOC103468389 LOC103467187 LOC103467187 LOC103463959 LOC103463959 LOC103461096 LOC103461096 supv3l1 supv3l1 dpyd dpyd HNMT HNMT LOC103460763 LOC103460763 LOC103464155 LOC103464155 LOC103464156 LOC103464156 LOC103464157 LOC103464157 Zpr1 Zpr1 exosc2 exosc2 trir trir LOC103461057 LOC103461057 ENSPREP00000020833 ENSPREP00000020833 helz2 helz2 ENSPREP00000020406 ENSPREP00000020406 dnph1 dnph1 LOC103468411 LOC103468411 ENSPREP00000019998 ENSPREP00000019998 magoh magoh zfp36l1 zfp36l1 LOC103469615 LOC103469615 cnot8 cnot8 entpd6 entpd6 mtpap mtpap nudt3 nudt3 LOC103470080 LOC103470080 LOC103470081 LOC103470081 dnase1l2 dnase1l2 xrn2 xrn2 nudt19 nudt19 ENSPREP00000018077 ENSPREP00000018077 Upf3b Upf3b dcp2 dcp2 rnaseh1 rnaseh1 dicer1 dicer1 nudt4 nudt4 blvra blvra casc3 casc3 LOC103478359 LOC103478359 nt5e nt5e LOC103476765 LOC103476765 LOC103463323 LOC103463323 nbas nbas exosc8 exosc8 LOC103475226 LOC103475226 cnot11 cnot11 exosc3 exosc3 ENSPREP00000016904 ENSPREP00000016904 PDE7B PDE7B lsm4 lsm4 UPF1 UPF1 dis3 dis3 smg1 smg1 cdadc1 cdadc1 lrrc27 lrrc27 dffb dffb LOC103480533 LOC103480533 LOC103480536 LOC103480536 CNP CNP samd4b samd4b zfp36l2 zfp36l2 haao haao entpd5 entpd5 aldh6a1 aldh6a1 tbp tbp smg6 smg6 tdo2 tdo2 LOC103479258 LOC103479258 ENSPREP00000014507 ENSPREP00000014507 LOC103479174 LOC103479174 pde4b pde4b exosc4 exosc4 lsm1 lsm1 dna2 dna2 LOC103457375 LOC103457375 Zcchc6 Zcchc6 ENSPREP00000013441 ENSPREP00000013441 TUT7 TUT7 LOC103473053 LOC103473053 aicda aicda rc3h2 rc3h2 LOC103479903 LOC103479903 dut dut ENSPREP00000012813 ENSPREP00000012813 LOC103472437 LOC103472437 upp2 upp2 dis3l dis3l rnaseh2b rnaseh2b nudt8 nudt8 cnot3 cnot3 LOC103468725 LOC103468725 ENSPREP00000010129 ENSPREP00000010129 noct noct LOC103460045 LOC103460045 LOC103466682 LOC103466682 LOC103477771 LOC103477771 DXO DXO LOC103477773 LOC103477773 LOC103470503 LOC103470503 entpd4 entpd4 gda gda mrto4 mrto4 LOC103477783 LOC103477783 LOC103466956 LOC103466956 LOC103457646 LOC103457646 smg8 smg8 NCBP1 NCBP1 CNOT2 CNOT2 eif4a3 eif4a3 tet2 tet2 entpd1 entpd1 LOC103465138 LOC103465138 ENSPREP00000008154 ENSPREP00000008154 LOC103466673 LOC103466673 Tymp Tymp zc3h12a zc3h12a ENSPREP00000007854 ENSPREP00000007854 ttc37 ttc37 Lin28a Lin28a LOC103479018 LOC103479018 wdr82 wdr82 LOC103461289 LOC103461289 dcp1b dcp1b smg9 smg9 pm20d1 pm20d1 LOC103460601 LOC103460601 patl1 patl1 ssb ssb LOC103471263 LOC103471263 lrpprc lrpprc cnot6l cnot6l QPRT QPRT mgat1 mgat1 dcps dcps nit1 nit1 mtrex mtrex PNPT1 PNPT1 kmo kmo LOC103480902 LOC103480902 dis3l2 dis3l2 LOC103464914 LOC103464914 skiv2l skiv2l snd1 snd1 exosc9 exosc9 LOC103472230 LOC103472230 etf1 etf1 LOC103463886 LOC103463886 nudt13 nudt13 mlh1 mlh1 urod urod pan2 pan2 itpa itpa cnot9 cnot9 ENSPREP00000000983 ENSPREP00000000983 LOC103472876 LOC103472876 dcp1a dcp1a ENSPREP00000000840 ENSPREP00000000840 ENSPREP00000000810 ENSPREP00000000810 afmid afmid exosc1 exosc1 LOC103464485 LOC103464485 parn parn LOC103456889 LOC103456889 Dctpp1 Dctpp1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lsm6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
peloProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
patl2PAT1 homolog 2. (593 aa)
LOC103464337Deoxyribonuclease; Belongs to the DNase I family. (269 aa)
LOC103459168Adenosine deaminase 2b. (485 aa)
pde12Phosphodiesterase 12. (586 aa)
Pde9aPhosphodiesterase 9A like; Belongs to the cyclic nucleotide phosphodiesterase family. (276 aa)
LOC103470954CCR4-NOT transcription complex, subunit 7. (286 aa)
LOC1034585795'-nucleotidase, cytosolic IAb. (366 aa)
mettl16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (550 aa)
kynuKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (463 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1263 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (104 aa)
rexo4REX4 homolog, 3'-5' exonuclease. (413 aa)
sarm1Sterile alpha and TIR motif containing 1. (752 aa)
NT5M5',3'-nucleotidase, mitochondrial. (230 aa)
pde5aPhosphodiesterase. (817 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (194 aa)
edc4Enhancer of mRNA decapping 4. (1333 aa)
LOC103474518Zgc:162730. (416 aa)
LOC103474517Zgc:114130. (430 aa)
xrn15'-3' exoribonuclease 1. (1705 aa)
LOC103470073Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa)
Ttc38Uncharacterized protein. (121 aa)
RIDAReactive intermediate imine deaminase A homolog. (136 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (960 aa)
LOC10346549610-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (902 aa)
LOC103466190CCR4-NOT transcription complex, subunit 2. (660 aa)
LOC103478615Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (339 aa)
adaAdenosine deaminase. (399 aa)
Fitm2Fat storage inducing transmembrane protein 2. (250 aa)
ENSPREP00000030212Nanos homolog 2; Belongs to the nanos family. (116 aa)
LOC103481179Adenosine deaminase 2a. (516 aa)
apobec2Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b. (306 aa)
LOC103458523Zgc:194887. (279 aa)
pde7aPhosphodiesterase. (506 aa)
mlycdMalonyl-CoA decarboxylase. (503 aa)
LOC103472139Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase b. (439 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (792 aa)
exosc6Exosome component 6. (274 aa)
ythdf2YTH N(6)-methyladenosine RNA binding protein 2. (639 aa)
LOC103473309Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism. (397 aa)
dmgdhDimethylglycine dehydrogenase. (870 aa)
blvrbBiliverdin reductase B. (205 aa)
smg7SMG7 nonsense mediated mRNA decay factor. (1158 aa)
pde8aPhosphodiesterase. (806 aa)
LOC103476883Tet methylcytosine dioxygenase 1. (1908 aa)
nudt12Nudix (nucleoside diphosphate linked moiety X)-type motif 12. (462 aa)
cnot1CCR4-NOT transcription complex, subunit 1. (2246 aa)
pde8bPhosphodiesterase. (818 aa)
samd4aSterile alpha motif domain containing 4A. (774 aa)
ENSPREP00000027416HD domain-containing protein. (178 aa)
LOC103467467SAM domain and HD domain 1. (627 aa)
smpdl3aSphingomyelin phosphodiesterase, acid-like 3A. (477 aa)
LOC103467464HD domain-containing protein. (433 aa)
tet3Tet methylcytosine dioxygenase 3. (2055 aa)
LOC103471741Uncharacterized protein. (297 aa)
cnot10CCR4-NOT transcription complex, subunit 10. (732 aa)
LOC103477584Deoxyribonuclease II, lysosomal. (376 aa)
ENSPREP00000026599Exosome component 7. (210 aa)
LOC103466095Nudix (nucleoside diphosphate linked moiety X)-type motif 4a. (181 aa)
pde4dPhosphodiesterase. (787 aa)
smg5SMG5 nonsense mediated mRNA decay factor. (1113 aa)
exosc5Exosome component 5. (236 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (396 aa)
ENSPREP00000026167F-box DNA helicase 1. (875 aa)
ascc3Activating signal cointegrator 1 complex subunit 3. (2197 aa)
deraDeoxyribose-phosphate aldolase (putative). (397 aa)
rbm8aRNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (160 aa)
nudt18Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (318 aa)
rc3h1Ring finger and CCCH-type domains 1b. (1119 aa)
LOC103475092Sb:cb81. (373 aa)
ctifCBP80/20-dependent translation initiation factor. (704 aa)
acot7Acyl-CoA thioesterase 7. (373 aa)
ENSPREP00000025150CCHC-type domain-containing protein. (157 aa)
LOC103463924Si:ch211-201h21.5. (326 aa)
LOC10345971010-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
lsm7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (130 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
LOC1034720335'-nucleotidase, cytosolic IAa. (387 aa)
lsm2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (93 aa)
upb1Ureidopropionase, beta. (383 aa)
atmNon-specific serine/threonine protein kinase. (3091 aa)
exosc10Exosome component 10. (892 aa)
acmsd2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
endogEndonuclease. (300 aa)
adalAdenosine deaminase-like. (353 aa)
edc3Enhancer of mRNA decapping 3 homolog (S. cerevisiae). (478 aa)
LOC103481886Uncharacterized protein. (302 aa)
mus81MUS81 structure-specific endonuclease subunit. (616 aa)
LOC103457893Aldedh domain-containing protein. (493 aa)
LOC103457894Ectonucleoside triphosphate diphosphohydrolase 5b; Belongs to the GDA1/CD39 NTPase family. (427 aa)
nudt5Nudix (nucleoside diphosphate linked moiety X)-type motif 5. (218 aa)
rnaseh2cRibonuclease H2, subunit C. (202 aa)
nudt7Nudix (nucleoside diphosphate linked moiety X)-type motif 7. (245 aa)
nudt9Nudix (nucleoside diphosphate linked moiety X)-type motif 9. (338 aa)
rnaseh2aRibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (296 aa)
allcAllantoicase. (382 aa)
LOC103468389Heme oxygenase 1a. (170 aa)
LOC103467187Deoxyribonuclease; Belongs to the DNase I family. (288 aa)
LOC103463959Zgc:103559. (450 aa)
LOC103461096PINc domain-containing protein. (704 aa)
supv3l1SUV3-like helicase. (760 aa)
dpydDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
HNMTHistamine N-methyltransferase. (286 aa)
LOC103460763Histamine N-methyltransferase. (300 aa)
LOC103464155Uncharacterized protein. (245 aa)
LOC103464156Deoxyribonuclease II beta. (352 aa)
LOC103464157Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (299 aa)
Zpr1ZPR1 zinc finger. (446 aa)
exosc2Exosome component 2. (293 aa)
trirTelomerase RNA component interacting RNase. (148 aa)
LOC103461057SET domain and mariner transposase fusion gene. (292 aa)
ENSPREP00000020833Ribonuclease T2; Belongs to the RNase T2 family. (166 aa)
helz2C3H1-type domain-containing protein. (2437 aa)
ENSPREP00000020406Uncharacterized protein. (137 aa)
dnph12'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. (144 aa)
LOC103468411Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (277 aa)
ENSPREP00000019998Exonuclease domain-containing protein. (263 aa)
magohMago homolog, exon junction complex subunit. (149 aa)
zfp36l1Zinc finger protein 36, C3H type-like 1a. (358 aa)
LOC103469615Ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2; Belongs to the GDA1/CD39 NTPase family. (493 aa)
cnot8CCR4-NOT transcription complex, subunit 8. (285 aa)
entpd6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (429 aa)
mtpapMitochondrial poly(A) polymerase. (583 aa)
nudt3Nudix (nucleoside diphosphate linked moiety X)-type motif 3b. (178 aa)
LOC103470080Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. (397 aa)
LOC103470081Hcy-binding domain-containing protein. (435 aa)
dnase1l2Deoxyribonuclease I. (328 aa)
xrn25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (943 aa)
nudt19Nudix (nucleoside diphosphate linked moiety X)-type motif 19. (393 aa)
ENSPREP00000018077Uncharacterized protein. (81 aa)
Upf3bUPF3B regulator of nonsense mediated mRNA decay. (149 aa)
dcp2Decapping mRNA 2. (398 aa)
rnaseh1Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (301 aa)
dicer1Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1860 aa)
nudt4Nudix (nucleoside diphosphate linked moiety X)-type motif 4b. (187 aa)
blvraBiliverdin reductase A. (323 aa)
casc3Casc3 exon junction complex subunit. (662 aa)
LOC103478359Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (480 aa)
nt5e5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (647 aa)
LOC103476765Uncharacterized protein. (409 aa)
LOC103463323Phosphodiesterase. (693 aa)
nbasNeuroblastoma amplified sequence. (2365 aa)
exosc8Exosome component 8. (279 aa)
LOC103475226IU_nuc_hydro domain-containing protein. (317 aa)
cnot11CCR4-NOT transcription complex, subunit 11. (445 aa)
exosc3Exosome component 3. (273 aa)
ENSPREP00000016904Uncharacterized protein. (90 aa)
PDE7BPhosphodiesterase. (528 aa)
lsm4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (188 aa)
UPF1UPF1 RNA helicase and ATPase. (1097 aa)
dis3DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (951 aa)
smg1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3658 aa)
cdadc1Cytidine and dCMP deaminase domain containing 1. (461 aa)
lrrc27Uncharacterized protein. (407 aa)
dffbDNA fragmentation factor, beta polypeptide (caspase-activated DNase). (346 aa)
LOC103480533Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (133 aa)
LOC103480536Methyltransferase like 3; Belongs to the MT-A70-like family. (287 aa)
CNP2',3'-cyclic nucleotide 3' phosphodiesterase. (653 aa)
samd4bSterile alpha motif domain containing 4B. (673 aa)
zfp36l2Zinc finger protein 36, C3H type-like 2. (404 aa)
haao3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (287 aa)
entpd5Ectonucleoside triphosphate diphosphohydrolase 5a; Belongs to the GDA1/CD39 NTPase family. (496 aa)
aldh6a1Aldehyde dehydrogenase 6 family member A1. (526 aa)
tbpTATA box binding protein. (301 aa)
smg6SMG6 nonsense mediated mRNA decay factor. (1607 aa)
tdo2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (403 aa)
LOC103479258Uncharacterized protein. (1109 aa)
ENSPREP00000014507UBA_6 domain-containing protein. (200 aa)
LOC103479174Phosphodiesterase. (782 aa)
pde4bPhosphodiesterase. (644 aa)
exosc4Exosome component 4. (245 aa)
lsm1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
dna2Uncharacterized protein. (1328 aa)
LOC1034573755'-nucleotidase, cytosolic IB b. (367 aa)
Zcchc6Uncharacterized protein. (187 aa)
ENSPREP00000013441Uncharacterized protein. (138 aa)
TUT7Terminal uridylyl transferase 7. (673 aa)
LOC103473053Uncharacterized protein; Belongs to the argonaute family. (695 aa)
aicdaActivation-induced cytidine deaminase. (211 aa)
rc3h2Ring finger and CCCH-type domains 2. (1110 aa)
LOC103479903Si:dkey-4e7.3. (394 aa)
dutDeoxyuridine triphosphatase. (200 aa)
ENSPREP00000012813Nudix (nucleoside diphosphate linked moiety X)-type motif 1. (140 aa)
LOC103472437Reactive intermediate imine deaminase A homolog. (137 aa)
upp2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (283 aa)
dis3lDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (974 aa)
rnaseh2bRibonuclease H2, subunit B. (306 aa)
nudt8Nudix hydrolase domain-containing protein. (390 aa)
cnot3CCR4-NOT transcription complex, subunit 3a. (894 aa)
LOC103468725Phosphodiesterase. (746 aa)
ENSPREP00000010129Uncharacterized protein. (107 aa)
noctNocturnin. (445 aa)
LOC103460045Ribonuclease T2, like; Belongs to the RNase T2 family. (269 aa)
LOC103466682Zinc finger, CCHC domain containing 7. (651 aa)
LOC103477771Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (867 aa)
DXODecapping exoribonuclease. (258 aa)
LOC103477773Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)
LOC103470503Indoleamine 2,3-dioxygenase 1. (422 aa)
entpd4Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (618 aa)
gdaGuanine deaminase. (482 aa)
mrto4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (237 aa)
LOC103477783Proline-rich nuclear receptor coactivator 2. (155 aa)
LOC103466956Deoxyribonuclease; Belongs to the DNase I family. (299 aa)
LOC103457646Lin-28 homolog B (C. elegans). (209 aa)
smg8SMG8 nonsense mediated mRNA decay factor. (917 aa)
NCBP1Nuclear cap binding protein subunit 1. (797 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (522 aa)
eif4a3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (406 aa)
tet2Tet methylcytosine dioxygenase 2. (1761 aa)
entpd1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (498 aa)
LOC103465138Uncharacterized protein. (603 aa)
ENSPREP00000008154UPF3A regulator of nonsense mediated mRNA decay. (171 aa)
LOC103466673Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (1001 aa)
TympThymidine phosphorylase. (150 aa)
zc3h12aZinc finger CCCH-type containing 12A. (623 aa)
ENSPREP00000007854Uncharacterized protein. (143 aa)
ttc37Tetratricopeptide repeat domain 37. (1569 aa)
Lin28aCCHC-type domain-containing protein. (202 aa)
LOC103479018Phosphodiesterase. (758 aa)
wdr82WD repeat domain 82. (302 aa)
LOC103461289Phosphodiesterase. (447 aa)
dcp1bDecapping mRNA 1B. (631 aa)
smg9SMG9 nonsense mediated mRNA decay factor. (507 aa)
pm20d1Peptidase M20 domain containing 1, tandem duplicate 2. (520 aa)
LOC103460601Heme oxygenase 2b. (316 aa)
patl1PAT1 homolog 1, processing body mRNA decay factor. (734 aa)
ssbSmall RNA binding exonuclease protection factor La. (382 aa)
LOC103471263CCR4-NOT transcription complex, subunit 6a. (550 aa)
lrpprcLeucine-rich pentatricopeptide repeat containing. (1421 aa)
cnot6lCCR4-NOT transcription complex, subunit 6-like. (555 aa)
QPRTNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (296 aa)
mgat1Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a. (440 aa)
dcpsDecapping enzyme, scavenger. (330 aa)
nit1Nitrilase 1. (318 aa)
mtrexMtr4 exosome RNA helicase. (1053 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (728 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (480 aa)
LOC103480902Si:ch211-133n4.4. (342 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1060 aa)
LOC103464914Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (170 aa)
skiv2lSKI2 homolog, superkiller viralicidic activity 2-like. (1180 aa)
snd1Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (911 aa)
exosc9Exosome component 9. (461 aa)
LOC103472230Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (894 aa)
etf1Eukaryotic translation termination factor 1b. (437 aa)
LOC103463886Nocturnin. (385 aa)
nudt13Nudix (nucleoside diphosphate linked moiety X)-type motif 13. (348 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (726 aa)
urodUroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (368 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1211 aa)
itpaInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (195 aa)
cnot9CCR4-NOT transcription complex subunit 9. (299 aa)
ENSPREP00000000983Not3 domain-containing protein. (459 aa)
LOC103472876CCR4-NOT transcription complex, subunit 3b. (938 aa)
dcp1aDecapping mRNA 1A. (491 aa)
ENSPREP00000000840Uncharacterized protein. (140 aa)
ENSPREP00000000810Uncharacterized protein. (142 aa)
afmidKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (292 aa)
exosc1Exosome component 1. (179 aa)
LOC103464485Heme oxygenase 2a. (365 aa)
parnPoly(A)-specific ribonuclease (deadenylation nuclease). (683 aa)
LOC103456889Phosphodiesterase. (874 aa)
Dctpp1dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (160 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (18%) [HD]