(104 nodes) Biological process involved in symbiotic interaction network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vps37b	Zgc:114173. (284 aa)
	ENSPREP00000022754	Vesicle-associated membrane protein 8 (endobrevin). (118 aa)
	ENSPREP00000022805	V-SNARE coiled-coil homology domain-containing protein. (116 aa)
	ENSPREP00000023036	Uncharacterized protein. (364 aa)
	LOC103460487	Fibronectin 1a. (2502 aa)
	ENSPREP00000023437	Uncharacterized protein. (97 aa)
	oxt	Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (138 aa)
	nectin1	Nectin cell adhesion molecule 1b. (508 aa)
	LOC103473227	Phosphatidylinositol 4-kinase, catalytic, alpha a; Belongs to the PI3/PI4-kinase family. (2095 aa)
	Ctdp1	FCP1 homology domain-containing protein. (271 aa)
	ptx3	Pentraxin 3, long b. (445 aa)
	pikfyve	Phosphoinositide kinase, FYVE finger containing. (2073 aa)
	LOC103470783	CARD domain-containing protein. (434 aa)
	ENSPREP00000025758	Peptidase S72 domain-containing protein. (799 aa)
	LOC103468460	E1A binding protein p300 b. (2737 aa)
	igf2r	Insulin-like growth factor 2 receptor. (1923 aa)
	LOC103467691	Peptidoglycan recognition protein 2. (489 aa)
	snw1	SNW domain containing 1. (536 aa)
	sap30bp	SAP30 binding protein. (209 aa)
	LOC103466144	Zgc:123278. (130 aa)
	tsg101	Tumor susceptibility 101a. (390 aa)
	ENSPREP00000029243	Pentaxin. (218 aa)
	pc	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1180 aa)
	slc3a2	Aamy domain-containing protein. (492 aa)
	RAB29	RAB29, member RAS oncogene family. (206 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1652 aa)
	ENSPREP00000030326	TNFR-Cys domain-containing protein. (260 aa)
	LOC103463808	Uncharacterized protein; Belongs to the AAA ATPase family. (411 aa)
	LOC103482005	E1A binding protein p300 a. (2743 aa)
	LOC103470941	Uncharacterized protein. (617 aa)
	siva1	SIVA1, apoptosis-inducing factor. (168 aa)
	dag1	Dystroglycan 1. (893 aa)
	ENSPREP00000031766	Uncharacterized protein. (309 aa)
	gas6	Uncharacterized protein. (650 aa)
	agtr1	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	ENSPREP00000032254	SCY domain-containing protein. (176 aa)
	LOC103480193	SCY domain-containing protein. (93 aa)
	napepld	Lactamase_B domain-containing protein. (293 aa)
	ENSPREP00000032598	Uncharacterized protein. (152 aa)
	tpcn2	Uncharacterized protein. (683 aa)
	ist1	IST1 factor associated with ESCRT-III. (333 aa)
	LOC103474630	Si:dkey-202g17.3. (478 aa)
	LOC103478307	Si:dkey-33i11.1. (644 aa)
	ENSPREP00000020277	RBR-type E3 ubiquitin transferase. (158 aa)
	ENSPREP00000020034	JunE proto-oncogene, AP-1 transcription factor subunit. (310 aa)
	ppib	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	LOC103472476	Zgc:63863. (364 aa)
	YTHDC2	YTH domain containing 2. (1418 aa)
	LOC103460928	Two pore segment channel 3. (734 aa)
	LOC108165882	Uncharacterized protein. (74 aa)
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (617 aa)
	pi4ka	Phosphatidylinositol 4-kinase, catalytic, alpha b; Belongs to the PI3/PI4-kinase family. (2169 aa)
	psmc3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
	uvrag	UV radiation resistance associated gene. (743 aa)
	ENSPREP00000014507	UBA_6 domain-containing protein. (200 aa)
	cxadr	CXADR Ig-like cell adhesion molecule. (382 aa)
	tbc1d20	TBC1 domain family, member 20. (397 aa)
	LOC103465217	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	LOC103473017	Apolipoprotein Ea. (251 aa)
	LOC103465102	Tumor suppressor 2, mitochondrial calcium regulator b. (111 aa)
	phb	Prohibitin. (271 aa)
	LOC103469188	Transcription factor AP-4 (activating enhancer binding protein 4). (329 aa)
	sp1	Sp1 transcription factor. (593 aa)
	LOC103479092	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
	LOC103461485	TNFR-Cys domain-containing protein. (179 aa)
	thoc1	THO complex 1. (654 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (903 aa)
	LOC103479045	Uncharacterized protein. (335 aa)
	ENSPREP00000008498	Uncharacterized protein. (286 aa)
	ENSPREP00000008452	Uncharacterized protein. (277 aa)
	LOC103467068	TNFR-Cys domain-containing protein. (271 aa)
	Trim62	Tripartite motif containing 62, tandem duplicate 1. (278 aa)
	zc3h12a	Zinc finger CCCH-type containing 12A. (623 aa)
	LOC103459310	N-acyl phosphatidylethanolamine phospholipase D. (268 aa)
	LOC103464509	Tumor suppressor 2, mitochondrial calcium regulator. (109 aa)
	LOC103477848	Apolipoprotein Eb. (265 aa)
	ddb1	Damage-specific DNA binding protein 1. (1102 aa)
	hmga2	Uncharacterized protein. (115 aa)
	ENSPREP00000006306	Uncharacterized protein. (79 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (437 aa)
	LOC103468796	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	LOC103481513	Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (423 aa)
	LOC103481511	Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (256 aa)
	ENSPREP00000005286	Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (419 aa)
	LOC103458108	Solute carrier family 3 member 2b. (567 aa)
	vps4a	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (436 aa)
	Cav1	Uncharacterized protein. (84 aa)
	lef1	Lymphoid enhancer-binding factor 1. (422 aa)
	ENSPREP00000002978	Uncharacterized protein. (84 aa)
	ENSPREP00000002835	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (282 aa)
	tpcn1	Two pore segment channel 1. (832 aa)
	LOC103479517	Nectin cell adhesion molecule 4b. (534 aa)
	LOC103480171	Ig-like domain-containing protein. (523 aa)
	TFAP4	Transcription factor AP-4. (317 aa)
	ENSPREP00000000285	Uncharacterized protein. (267 aa)
	ENSPREP00000000284	Uncharacterized protein. (432 aa)
	ENSPREP00000000283	Uncharacterized protein. (409 aa)
	ENSPREP00000000282	Uncharacterized protein. (201 aa)
	ENSPREP00000020340	Uncharacterized protein. (401 aa)
	hpn	Hepsin; Belongs to the peptidase S1 family. (427 aa)
	jpt2	Jupiter microtubule associated homolog 2. (218 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (602 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (490 aa)
	thoc3	THO complex 3. (349 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cav1	LOC103477848	ENSPREP00000003891	ENSPREP00000006664	Uncharacterized protein.	Apolipoprotein Eb.	0.418
ENSPREP00000002835	LOC103468460	ENSPREP00000002835	ENSPREP00000026558	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	E1A binding protein p300 b.	0.792
ENSPREP00000002835	LOC103482005	ENSPREP00000002835	ENSPREP00000030842	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	E1A binding protein p300 a.	0.792
ENSPREP00000002835	sp1	ENSPREP00000002835	ENSPREP00000011446	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Sp1 transcription factor.	0.683
ENSPREP00000020034	LOC103468460	ENSPREP00000020034	ENSPREP00000026558	JunE proto-oncogene, AP-1 transcription factor subunit.	E1A binding protein p300 b.	0.792
ENSPREP00000020034	LOC103482005	ENSPREP00000020034	ENSPREP00000030842	JunE proto-oncogene, AP-1 transcription factor subunit.	E1A binding protein p300 a.	0.792
ENSPREP00000020034	sp1	ENSPREP00000020034	ENSPREP00000011446	JunE proto-oncogene, AP-1 transcription factor subunit.	Sp1 transcription factor.	0.683
ENSPREP00000022754	igf2r	ENSPREP00000022754	ENSPREP00000026805	Vesicle-associated membrane protein 8 (endobrevin).	Insulin-like growth factor 2 receptor.	0.514
ENSPREP00000022805	igf2r	ENSPREP00000022805	ENSPREP00000026805	V-SNARE coiled-coil homology domain-containing protein.	Insulin-like growth factor 2 receptor.	0.514
ENSPREP00000025758	dag1	ENSPREP00000025758	ENSPREP00000031725	Peptidase S72 domain-containing protein.	Dystroglycan 1.	0.901
ENSPREP00000030326	LOC103461485	ENSPREP00000030326	ENSPREP00000010220	TNFR-Cys domain-containing protein.	TNFR-Cys domain-containing protein.	0.902
ENSPREP00000032254	LOC103480193	ENSPREP00000032254	ENSPREP00000032274	SCY domain-containing protein.	SCY domain-containing protein.	0.438
LOC103458108	LOC103474630	ENSPREP00000005043	ENSPREP00000033832	Solute carrier family 3 member 2b.	Si:dkey-202g17.3.	0.900
LOC103458108	slc3a2	ENSPREP00000005043	ENSPREP00000029732	Solute carrier family 3 member 2b.	Aamy domain-containing protein.	0.904
LOC103461485	ENSPREP00000030326	ENSPREP00000010220	ENSPREP00000030326	TNFR-Cys domain-containing protein.	TNFR-Cys domain-containing protein.	0.902
LOC103463808	LOC103466144	ENSPREP00000030659	ENSPREP00000028587	Uncharacterized protein; Belongs to the AAA ATPase family.	Zgc:123278.	0.459
LOC103463808	VPS4B	ENSPREP00000030659	ENSPREP00000006219	Uncharacterized protein; Belongs to the AAA ATPase family.	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.	0.900
LOC103463808	ist1	ENSPREP00000030659	ENSPREP00000033429	Uncharacterized protein; Belongs to the AAA ATPase family.	IST1 factor associated with ESCRT-III.	0.948
LOC103463808	tsg101	ENSPREP00000030659	ENSPREP00000028752	Uncharacterized protein; Belongs to the AAA ATPase family.	Tumor susceptibility 101a.	0.459
LOC103463808	vps4a	ENSPREP00000030659	ENSPREP00000004964	Uncharacterized protein; Belongs to the AAA ATPase family.	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family.	0.938