(19 nodes) T cell selection network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cd3e	Ig_4 domain-containing protein. (185 aa)
	batf	Basic leucine zipper transcription factor, ATF-like. (124 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	LOC103468544	Guanylate kinase-like domain-containing protein. (308 aa)
	ENSPREP00000027430	CARD domain-containing protein. (524 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
	LOC103478148	Interleukin 6 receptor. (603 aa)
	tbx21	T-box transcription factor 21. (614 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1230 aa)
	Mtor	Serine/threonine-protein kinase TOR. (1001 aa)
	ENSPREP00000016378	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (702 aa)
	srf	Serum response factor b. (570 aa)
	LOC103468233	Tyrosine-protein kinase. (606 aa)
	LOC103474821	Uncharacterized protein. (175 aa)
	LOC103475178	Ig_4 domain-containing protein. (169 aa)
	SRF	Serum response factor. (243 aa)
	themis2	Thymocyte selection associated family member 2. (703 aa)
	syk	Tyrosine-protein kinase. (614 aa)
	ENSPREP00000005271	Uncharacterized protein. (210 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000016378	Mtor	ENSPREP00000016378	ENSPREP00000016474	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase TOR.	0.934
ENSPREP00000016378	atg5	ENSPREP00000016378	ENSPREP00000028618	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.456
ENSPREP00000016378	stk11	ENSPREP00000016378	ENSPREP00000026606	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine kinase 11; Belongs to the protein kinase superfamily.	0.547
ENSPREP00000027430	LOC103468233	ENSPREP00000027430	ENSPREP00000012417	CARD domain-containing protein.	Tyrosine-protein kinase.	0.511
ENSPREP00000027430	LOC103468544	ENSPREP00000027430	ENSPREP00000027446	CARD domain-containing protein.	Guanylate kinase-like domain-containing protein.	0.900
ENSPREP00000027430	syk	ENSPREP00000027430	ENSPREP00000006334	CARD domain-containing protein.	Tyrosine-protein kinase.	0.478
LOC103468233	ENSPREP00000027430	ENSPREP00000012417	ENSPREP00000027430	Tyrosine-protein kinase.	CARD domain-containing protein.	0.511
LOC103468233	LOC103468544	ENSPREP00000012417	ENSPREP00000027446	Tyrosine-protein kinase.	Guanylate kinase-like domain-containing protein.	0.511
LOC103468233	LOC103474821	ENSPREP00000012417	ENSPREP00000010465	Tyrosine-protein kinase.	Uncharacterized protein.	0.812
LOC103468233	LOC103475178	ENSPREP00000012417	ENSPREP00000010394	Tyrosine-protein kinase.	Ig_4 domain-containing protein.	0.859
LOC103468233	cd3e	ENSPREP00000012417	ENSPREP00000010409	Tyrosine-protein kinase.	Ig_4 domain-containing protein.	0.859
LOC103468544	ENSPREP00000027430	ENSPREP00000027446	ENSPREP00000027430	Guanylate kinase-like domain-containing protein.	CARD domain-containing protein.	0.900
LOC103468544	LOC103468233	ENSPREP00000027446	ENSPREP00000012417	Guanylate kinase-like domain-containing protein.	Tyrosine-protein kinase.	0.511
LOC103468544	syk	ENSPREP00000027446	ENSPREP00000006334	Guanylate kinase-like domain-containing protein.	Tyrosine-protein kinase.	0.478
LOC103474821	LOC103468233	ENSPREP00000010465	ENSPREP00000012417	Uncharacterized protein.	Tyrosine-protein kinase.	0.812
LOC103474821	LOC103475178	ENSPREP00000010465	ENSPREP00000010394	Uncharacterized protein.	Ig_4 domain-containing protein.	0.991
LOC103474821	cd3e	ENSPREP00000010465	ENSPREP00000010409	Uncharacterized protein.	Ig_4 domain-containing protein.	0.991
LOC103474821	ptprc	ENSPREP00000010465	ENSPREP00000018309	Uncharacterized protein.	Protein tyrosine phosphatase receptor type C.	0.734
LOC103474821	syk	ENSPREP00000010465	ENSPREP00000006334	Uncharacterized protein.	Tyrosine-protein kinase.	0.812
LOC103475178	LOC103468233	ENSPREP00000010394	ENSPREP00000012417	Ig_4 domain-containing protein.	Tyrosine-protein kinase.	0.859