STRINGSTRING
slc6a3 slc6a3 LOC103462236 LOC103462236 SMURF2 SMURF2 pllp pllp LOC103469311 LOC103469311 LOC103469310 LOC103469310 LOC103457562 LOC103457562 LOC103479524 LOC103479524 LOC103477151 LOC103477151 ENSPREP00000002302 ENSPREP00000002302 LOC103476448 LOC103476448 ENSPREP00000002653 ENSPREP00000002653 LOC103471313 LOC103471313 LOC103480848 LOC103480848 ret ret Cav1 Cav1 cav2 cav2 akap6 akap6 PLPP1 PLPP1 LOC103466888 LOC103466888 ENSPREP00000004666 ENSPREP00000004666 vdac1 vdac1 LOC103462732 LOC103462732 LOC103482185 LOC103482185 LOC103464552 LOC103464552 lrrk2 lrrk2 kcnq1 kcnq1 LOC103477855 LOC103477855 smo smo psen2 psen2 unc5a unc5a serpinh1 serpinh1 LOC103464471 LOC103464471 Rtn4r Rtn4r stoml2 stoml2 park7 park7 ENSPREP00000008810 ENSPREP00000008810 LOC103480941 LOC103480941 slc6a2 slc6a2 LOC103479635 LOC103479635 slc6a4 slc6a4 Cln6 Cln6 lamtor4 lamtor4 flot2 flot2 aqp1 aqp1 cln3 cln3 ENSPREP00000010780 ENSPREP00000010780 LYPD6 LYPD6 LOC103472976 LOC103472976 tlr2 tlr2 pag1 pag1 LOC103480351 LOC103480351 p2rx1 p2rx1 LOC103479149 LOC103479149 LOC103458271 LOC103458271 LOC103473021 LOC103473021 cav3 cav3 LOC103465217 LOC103465217 LOC103463403 LOC103463403 LOC103469402 LOC103469402 ppt1 ppt1 LOC103475595 LOC103475595 LOC103481184 LOC103481184 ENSPREP00000015283 ENSPREP00000015283 LOC103456974 LOC103456974 mal2 mal2 LOC103476145 LOC103476145 plpp2 plpp2 LOC103480979 LOC103480979 tnfrsf1a tnfrsf1a tgfbr2 tgfbr2 LOC103468990 LOC103468990 LOC103456983 LOC103456983 lamtor3 lamtor3 LOC103463553 LOC103463553 trpc4 trpc4 nphs2 nphs2 smpd2 smpd2 il6st il6st LOC103458418 LOC103458418 LOC103481247 LOC103481247 ptprc ptprc LOC103474773 LOC103474773 LOC103463294 LOC103463294 LOC103477977 LOC103477977 p2rx7 p2rx7 flot1 flot1 LOC103474979 LOC103474979 STOML3 STOML3 ENSPREP00000020797 ENSPREP00000020797 LOC103461074 LOC103461074 lamtor5 lamtor5 cd79a cd79a lipe lipe LOC103475509 LOC103475509 scarb1 scarb1 Adam17 Adam17 ENSPREP00000021987 ENSPREP00000021987 LOC103470110 LOC103470110 LOC103477907 LOC103477907 LOC103476312 LOC103476312 LOC103468522 LOC103468522 LOC103469131 LOC103469131 ENSPREP00000024223 ENSPREP00000024223 LOC103482088 LOC103482088 inpp5d inpp5d podxl podxl LOC103458871 LOC103458871 pikfyve pikfyve lamtor2 lamtor2 ENSPREP00000025758 ENSPREP00000025758 LOC103471360 LOC103471360 TGFBR2 TGFBR2 smurf1 smurf1 ENSPREP00000027430 ENSPREP00000027430 LOC103468544 LOC103468544 LOC103473499 LOC103473499 emp2 emp2 slc1a2 slc1a2 LOC103481123 LOC103481123 LOC103481154 LOC103481154 LOC103457610 LOC103457610 ENSPREP00000028578 ENSPREP00000028578 LOC103477637 LOC103477637 lamtor1 lamtor1 LOC103469815 LOC103469815 LOC103461893 LOC103461893 LOC103461875 LOC103461875 adcy8 adcy8 LOC103475233 LOC103475233 mlc1 mlc1 cavin4 cavin4 plpp3 plpp3 htr2a htr2a dag1 dag1 LOC103473970 LOC103473970 LOC103474002 LOC103474002 cbl cbl LOC103459298 LOC103459298 LOC103470329 LOC103470329 KIF18A KIF18A p2rx3 p2rx3 neu3 neu3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
slc6a3Solute carrier family 6 member 3. (602 aa)
LOC103462236ATP-binding cassette, sub-family G (WHITE), member 2c. (594 aa)
SMURF2E3 ubiquitin-protein ligase. (776 aa)
pllpPlasmolipin. (183 aa)
LOC103469311Zgc:77748. (283 aa)
LOC103469310Uncharacterized protein. (287 aa)
LOC103457562Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1185 aa)
LOC103479524Si:dkeyp-66d1.7. (293 aa)
LOC103477151Uncharacterized protein. (158 aa)
ENSPREP00000002302ATP-binding cassette, sub-family G (WHITE), member 2d. (603 aa)
LOC103476448Mal, T cell differentiation protein b. (155 aa)
ENSPREP00000002653MARVEL domain-containing protein. (154 aa)
LOC103471313Toll-like receptor 1. (804 aa)
LOC103480848ATP-binding cassette, sub-family G (WHITE), member 2a. (633 aa)
retProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1118 aa)
Cav1Uncharacterized protein. (84 aa)
cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (177 aa)
akap6A kinase (PRKA) anchor protein 6. (2553 aa)
PLPP1Phospholipid phosphatase 1a. (277 aa)
LOC103466888Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (172 aa)
ENSPREP00000004666Si:dkey-237i9.8. (616 aa)
vdac1Voltage-dependent anion channel 1. (258 aa)
LOC103462732Amino acid transporter. (559 aa)
LOC103482185Caveolae associated protein 1b. (397 aa)
LOC103464552Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (184 aa)
lrrk2Leucine-rich repeat kinase 2. (2573 aa)
kcnq1Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (631 aa)
LOC103477855Uncharacterized protein. (678 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)
psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (430 aa)
unc5aUnc-5 netrin receptor A. (903 aa)
serpinh1Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b; Belongs to the serpin family. (405 aa)
LOC103464471Tumor necrosis factor receptor superfamily, member 1B. (441 aa)
Rtn4rReticulon 4 receptor. (452 aa)
stoml2Stomatin (EPB72)-like 2. (351 aa)
park7Parkinson protein 7. (189 aa)
ENSPREP00000008810Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (962 aa)
LOC103480941TIR domain-containing protein. (809 aa)
slc6a2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (700 aa)
LOC103479635Death domain-containing protein. (536 aa)
slc6a4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (714 aa)
Cln6CLN6 transmembrane ER protein a. (290 aa)
lamtor4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (98 aa)
flot2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (434 aa)
aqp1Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (268 aa)
cln3Battenin. (480 aa)
ENSPREP00000010780Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (176 aa)
LYPD6LY6/PLAUR domain containing 6. (179 aa)
LOC103472976Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (350 aa)
tlr2TIR domain-containing protein; Belongs to the Toll-like receptor family. (768 aa)
pag1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (447 aa)
LOC103480351Uncharacterized protein. (282 aa)
p2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (421 aa)
LOC103479149Uncharacterized protein. (678 aa)
LOC103458271Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (388 aa)
LOC103473021Lipase, hormone-sensitive a. (682 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (163 aa)
LOC103465217Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
LOC103463403Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1126 aa)
LOC103469402Caveolae associated protein 1a. (393 aa)
ppt1Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (388 aa)
LOC103475595Reticulon 4 receptor-like 1a. (454 aa)
LOC103481184Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1181 aa)
ENSPREP00000015283Reticulon 4 receptor-like 1b. (451 aa)
LOC103456974Caveolae associated protein 4b. (311 aa)
mal2Mal, T cell differentiation protein 2 (gene/pseudogene). (186 aa)
LOC103476145Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family. (468 aa)
plpp2Phospholipid phosphatase 2a. (287 aa)
LOC103480979Uncharacterized protein. (406 aa)
tnfrsf1aTumor necrosis factor receptor superfamily, member 1a. (333 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (591 aa)
LOC103468990Amino acid transporter. (675 aa)
LOC103456983PHB domain-containing protein. (275 aa)
lamtor3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (135 aa)
LOC103463553Phospholipid phosphatase 2b. (289 aa)
trpc4Transient receptor potential cation channel, subfamily C, member 4a; Belongs to the transient receptor (TC 1.A.4) family. (956 aa)
nphs2NPHS2 stomatin family member, podocin. (376 aa)
smpd2Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase). (440 aa)
il6stUncharacterized protein. (896 aa)
LOC103458418Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family. (384 aa)
LOC103481247Transient receptor potential cation channel, subfamily C, member 5a; Belongs to the transient receptor (TC 1.A.4) family. (1139 aa)
ptprcProtein tyrosine phosphatase receptor type C. (1230 aa)
LOC103474773Glycoprotein M6Ba. (372 aa)
LOC103463294Plasmalemma vesicle associated protein b. (460 aa)
LOC103477977Uncharacterized protein. (439 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (580 aa)
flot1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
LOC103474979Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (954 aa)
STOML3Stomatin (EPB72)-like 3a. (267 aa)
ENSPREP00000020797TNFR-Cys domain-containing protein. (307 aa)
LOC103461074Uncharacterized protein; Belongs to the CD36 family. (95 aa)
lamtor5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (118 aa)
cd79aCD79a molecule, immunoglobulin-associated alpha. (221 aa)
lipeLipase, hormone-sensitive b. (825 aa)
LOC103475509Stomatin (EPB72)-like 3b. (273 aa)
scarb1Scavenger receptor class B, member 1; Belongs to the CD36 family. (490 aa)
Adam17Pep_M12B_propep domain-containing protein. (290 aa)
ENSPREP00000021987ADAM metallopeptidase domain 17b. (508 aa)
LOC103470110acidPPc domain-containing protein. (279 aa)
LOC103477907Cbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
LOC103476312Uncharacterized protein. (857 aa)
LOC103468522E3 ubiquitin-protein ligase. (770 aa)
LOC103469131Platelet/endothelial cell adhesion molecule 1. (797 aa)
ENSPREP00000024223Uncharacterized protein. (147 aa)
LOC103482088Neutral ceramidase. (611 aa)
inpp5dInositol polyphosphate-5-phosphatase D. (1102 aa)
podxlUncharacterized protein. (437 aa)
LOC103458871ADAM metallopeptidase domain 17a. (800 aa)
pikfyvePhosphoinositide kinase, FYVE finger containing. (2073 aa)
lamtor2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (95 aa)
ENSPREP00000025758Peptidase S72 domain-containing protein. (799 aa)
LOC103471360Reticulon 4 receptor-like 2b. (463 aa)
TGFBR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (544 aa)
smurf1E3 ubiquitin-protein ligase. (729 aa)
ENSPREP00000027430CARD domain-containing protein. (524 aa)
LOC103468544Guanylate kinase-like domain-containing protein. (308 aa)
LOC103473499Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (435 aa)
emp2Epithelial membrane protein 2. (165 aa)
slc1a2Amino acid transporter. (537 aa)
LOC103481123Uncharacterized protein. (280 aa)
LOC103481154MARVEL domain-containing protein. (288 aa)
LOC103457610BAALC binder of MAP3K1 and KLF4 b. (175 aa)
ENSPREP00000028578Ion_trans domain-containing protein; Belongs to the potassium channel family. (424 aa)
LOC103477637Toll-like receptor 18. (882 aa)
lamtor1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
LOC103469815Mal, T cell differentiation protein a. (158 aa)
LOC103461893Caveolae associated protein 2a. (470 aa)
LOC103461875Tissue factor pathway inhibitor. (263 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1239 aa)
LOC103475233Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
mlc1Modulator of VRAC current 1. (404 aa)
cavin4Caveolae associated protein 4a. (295 aa)
plpp3Phospholipid phosphatase 3. (313 aa)
htr2a5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (496 aa)
dag1Dystroglycan 1. (893 aa)
LOC103473970Stomatin. (275 aa)
LOC103474002Stomatin. (295 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (848 aa)
LOC103459298CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (409 aa)
LOC103470329Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (568 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (909 aa)
p2rx3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (415 aa)
neu3Sialidase 3 (membrane sialidase), tandem duplicate 1. (464 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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