STRINGSTRING
dazl dazl eif2s2 eif2s2 EIF4E3 EIF4E3 gtpbp1 gtpbp1 MARF1 MARF1 LOC103480295 LOC103480295 eif3l eif3l gfm1 gfm1 EEF1A1 EEF1A1 SHMT2 SHMT2 eif4b eif4b etf1 etf1 LOC103480164 LOC103480164 LOC103472230 LOC103472230 eif3a eif3a eif2b3 eif2b3 mif4gd mif4gd mtrf1l mtrf1l LOC103460523 LOC103460523 ENSPREP00000004018 ENSPREP00000004018 dhx29 dhx29 LOC103479599 LOC103479599 cpeb3 cpeb3 ENSPREP00000004501 ENSPREP00000004501 fmr1 fmr1 LOC103465618 LOC103465618 LOC103480125 LOC103480125 eif1ad eif1ad EEF1A1-2 EEF1A1-2 eif2ak1 eif2ak1 EIF4E3-2 EIF4E3-2 ENSPREP00000006996 ENSPREP00000006996 mtif2 mtif2 eif5 eif5 eif4a3 eif4a3 cpeb1 cpeb1 rpl10 rpl10 CPEB4 CPEB4 LOC103456837 LOC103456837 eif3b eif3b eif3g eif3g eif4a2 eif4a2 LOC103477773 LOC103477773 LOC103477771 LOC103477771 eif2ak3 eif2ak3 LOC103471867 LOC103471867 NANOS1 NANOS1 LOC103477270 LOC103477270 ENSPREP00000011628 ENSPREP00000011628 rps9 rps9 LOC103477355 LOC103477355 LOC103468154 LOC103468154 eloa eloa LOC103472994 LOC103472994 cnbp cnbp eef2 eef2 eif2s1 eif2s1 shmt2 shmt2 LOC103473053 LOC103473053 paip1 paip1 EIF4G1 EIF4G1 eef1d eef1d LOC103471822 LOC103471822 samd4b samd4b zar1l zar1l eef1b2 eef1b2 eif5a2 eif5a2 LOC103469494 LOC103469494 eif2s3 eif2s3 hbs1l hbs1l LOC103456988 LOC103456988 LOC103475009 LOC103475009 abcf1 abcf1 eefsec eefsec eif3h eif3h ENSPREP00000018229 ENSPREP00000018229 ENSPREP00000018802 ENSPREP00000018802 Eif3d Eif3d LOC103458414 LOC103458414 LOC103458413 LOC103458413 EIF5AL1 EIF5AL1 eif3m eif3m eif4g3 eif4g3 tufm tufm LOC103461055 LOC103461055 LOC103460327 LOC103460327 eif3e eif3e GTPBP2 GTPBP2 mtif3 mtif3 eif2d eif2d eif4ebp2 eif4ebp2 Eif4e2 Eif4e2 LOC103479844 LOC103479844 eef1g eef1g gspt1 gspt1 tsfm tsfm eif2b1 eif2b1 abtb1 abtb1 eif3i eif3i denr denr ctif ctif eef1e1 eef1e1 LOC103479455 LOC103479455 trim71 trim71 shmt1 shmt1 cpeb2 cpeb2 ENSPREP00000027516 ENSPREP00000027516 samd4a samd4a ENSPREP00000027804 ENSPREP00000027804 LOC103476881 LOC103476881 zar1 zar1 eif2b4 eif2b4 eif2b2 eif2b2 LOC103470867 LOC103470867 eif3f eif3f EIF2AK4 EIF2AK4 eif3k eif3k clg9h12orf65 clg9h12orf65 eif6 eif6 eif2b5 eif2b5 eif2a eif2a ENSPREP00000032704 ENSPREP00000032704 fxr1 fxr1 LOC103470876 LOC103470876 eif3j eif3j eif4g2 eif4g2 LOC103481398 LOC103481398
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dazlDeleted in azoospermia-like. (217 aa)
eif2s2Eukaryotic translation initiation factor 2, subunit 2 beta. (334 aa)
EIF4E3Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family. (227 aa)
gtpbp1GTP binding protein 1. (710 aa)
MARF1Meiosis regulator and mRNA stability factor 1. (1791 aa)
LOC103480295GTP binding protein 1, like. (666 aa)
eif3lEukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (648 aa)
gfm1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...] (788 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (530 aa)
eif4bEukaryotic translation initiation factor 4Bb. (639 aa)
etf1Eukaryotic translation termination factor 1b. (437 aa)
LOC103480164Fragile X mental retardation, autosomal homolog 2. (656 aa)
LOC103472230Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (894 aa)
eif3aEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1258 aa)
eif2b3Eukaryotic translation initiation factor 2B, subunit 3 gamma. (454 aa)
mif4gdMIF4G domain containing a. (221 aa)
mtrf1lMitochondrial translational release factor 1-like. (430 aa)
LOC103460523Eukaryotic translation initiation factor 4eb; Belongs to the eukaryotic initiation factor 4E family. (252 aa)
ENSPREP00000004018Eukaryotic translation initiation factor 4h. (220 aa)
dhx29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1373 aa)
LOC103479599Uncharacterized protein. (1715 aa)
cpeb3Cytoplasmic polyadenylation element binding protein 3. (666 aa)
ENSPREP00000004501Uncharacterized protein. (684 aa)
fmr1Fragile X mental retardation 1. (273 aa)
LOC103465618Eukaryotic translation initiation factor 4, gamma 2b. (936 aa)
LOC103480125Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family. (390 aa)
eif1adEukaryotic translation initiation factor 1A domain containing. (178 aa)
EEF1A1-2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (492 aa)
eif2ak1Eukaryotic translation initiation factor 2-alpha kinase 1. (660 aa)
EIF4E3-2Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family. (235 aa)
ENSPREP00000006996annotation not available (51 aa)
mtif2Mitochondrial translational initiation factor 2. (705 aa)
eif5Eukaryotic translation initiation factor 5. (433 aa)
eif4a3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (406 aa)
cpeb1Cytoplasmic polyadenylation element binding protein 1b. (609 aa)
rpl10Ribosomal protein L10. (215 aa)
CPEB4Cytoplasmic polyadenylation element binding protein 4. (761 aa)
LOC103456837Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (452 aa)
eif3bEukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (680 aa)
eif3gEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (306 aa)
eif4a2Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. (411 aa)
LOC103477773Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)
LOC103477771Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (867 aa)
eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1072 aa)
LOC103471867Nanos homolog 1; Belongs to the nanos family. (232 aa)
NANOS1Nanos C2HC-type zinc finger 1; Belongs to the nanos family. (221 aa)
LOC103477270Uncharacterized protein. (689 aa)
ENSPREP00000011628Uncharacterized protein. (564 aa)
rps9Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (136 aa)
LOC103477355Protein kinase domain-containing protein. (582 aa)
LOC103468154G1 to S phase transition 1, like. (639 aa)
eloaElongin A. (681 aa)
LOC103472994Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
cnbpCCHC-type zinc finger, nucleic acid binding protein a. (166 aa)
eef2Tr-type G domain-containing protein. (858 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (310 aa)
shmt2Serine hydroxymethyltransferase 2 (mitochondrial). (515 aa)
LOC103473053Uncharacterized protein; Belongs to the argonaute family. (695 aa)
paip1Poly(A) binding protein interacting protein 1. (395 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1733 aa)
eef1dEukaryotic translation elongation factor 1 delta. (811 aa)
LOC103471822Eukaryotic translation initiation factor 4ea; Belongs to the eukaryotic initiation factor 4E family. (215 aa)
samd4bSterile alpha motif domain containing 4B. (673 aa)
zar1lZygote arrest 1-like. (337 aa)
eef1b2Eukaryotic translation elongation factor 1 beta 2; Belongs to the EF-1-beta/EF-1-delta family. (187 aa)
eif5a2eIF-5a domain-containing protein. (187 aa)
LOC103469494Eukaryotic translation initiation factor 1B. (124 aa)
eif2s3Eukaryotic translation initiation factor 2, subunit 3 gamma. (472 aa)
hbs1lHBS1-like translational GTPase. (721 aa)
LOC103456988Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (152 aa)
LOC103475009RRM domain-containing protein. (335 aa)
abcf1ATP-binding cassette, sub-family F (GCN20), member 1. (766 aa)
eefsecEukaryotic elongation factor, selenocysteine-tRNA-specific. (577 aa)
eif3hEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (255 aa)
ENSPREP00000018229Uncharacterized protein. (54 aa)
ENSPREP00000018802Uncharacterized protein. (251 aa)
Eif3dUncharacterized protein. (58 aa)
LOC103458414Eukaryotic translation initiation factor 5A. (110 aa)
LOC103458413Eukaryotic translation initiation factor 5A-1-like. (110 aa)
EIF5AL1Eukaryotic translation initiation factor 5A. (155 aa)
eif3mEukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (375 aa)
eif4g3Eukaryotic translation initiation factor 4 gamma, 3a. (1445 aa)
tufmElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (446 aa)
LOC103461055Fragile X mental retardation 1. (400 aa)
LOC103460327Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (421 aa)
eif3eEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (492 aa)
GTPBP2GTP binding protein 2. (610 aa)
mtif3Mitochondrial translational initiation factor 3. (275 aa)
eif2dEukaryotic translation initiation factor 2D. (604 aa)
eif4ebp2Eukaryotic translation initiation factor 4E binding protein 2. (112 aa)
Eif4e2Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (222 aa)
LOC103479844Eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein); Belongs to the EF-1-beta/EF-1-delta family. (465 aa)
eef1gEukaryotic translation elongation factor 1 gamma. (437 aa)
gspt1G1 to S phase transition 1. (486 aa)
tsfmElongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (307 aa)
eif2b1Eukaryotic translation initiation factor 2B, subunit 1 alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (331 aa)
abtb1Ankyrin repeat and BTB (POZ) domain containing 1. (476 aa)
eif3iEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (378 aa)
denrDensity-regulated protein; Belongs to the DENR family. (196 aa)
ctifCBP80/20-dependent translation initiation factor. (704 aa)
eef1e1Eukaryotic translation elongation factor 1 epsilon 1. (172 aa)
LOC103479455Eukaryotic translation elongation factor 2b. (858 aa)
trim71Tripartite motif containing 71, E3 ubiquitin protein ligase. (831 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (442 aa)
cpeb2Cytoplasmic polyadenylation element binding protein 2. (555 aa)
ENSPREP00000027516Mitochondrial translational release factor 1. (228 aa)
samd4aSterile alpha motif domain containing 4A. (774 aa)
ENSPREP00000027804RF_PROK_I domain-containing protein. (169 aa)
LOC103476881Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
zar1Zygote arrest 1. (330 aa)
eif2b4Eukaryotic translation initiation factor 2B, subunit 4 delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (549 aa)
eif2b2Eukaryotic translation initiation factor 2B, subunit 2 beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (355 aa)
LOC103470867Cytoplasmic polyadenylation element binding protein 4a. (741 aa)
eif3fEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (273 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1652 aa)
eif3kEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (219 aa)
clg9h12orf65Si:ch211-275j6.5. (169 aa)
eif6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (255 aa)
eif2b5Eukaryotic translation initiation factor 2B, subunit 5 epsilon. (699 aa)
eif2aEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (582 aa)
ENSPREP00000032704TFIIS N-terminal domain-containing protein. (269 aa)
fxr1Fragile X mental retardation, autosomal homolog 1. (571 aa)
LOC103470876GTP binding protein 2b. (606 aa)
eif3jEukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (240 aa)
eif4g2Eukaryotic translation initiation factor 4, gamma 2a. (868 aa)
LOC103481398Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (857 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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