(19 nodes) Negative regulation of neuron differentiation network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	six6	SIX homeobox 6a. (245 aa)
	nepro	Nucleolus and neural progenitor protein. (475 aa)
	LOC103477376	Forkhead box G1d. (344 aa)
	lsm1	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
	lfng	Beta-1,3-N-acetylglucosaminyltransferase. (367 aa)
	phox2b	Paired like homeobox 2Bb. (285 aa)
	disp3	Dispatched RND transporter family member 3. (1335 aa)
	irx3	Iroquois homeobox 3a. (457 aa)
	LOC103481539	SIX homeobox 3b. (277 aa)
	dlx2	Distal-less homeobox 2b. (278 aa)
	dlx1	Distal-less homeobox 1a. (252 aa)
	LOC103474746	Fork-head domain-containing protein. (389 aa)
	Six3	SIX homeobox 3a. (341 aa)
	LOC103475931	SIX homeobox 7. (260 aa)
	foxg1	Forkhead box G1a. (346 aa)
	EIF4ENIF1	Eukaryotic translation initiation factor 4E nuclear import factor 1. (953 aa)
	lbx1	Homeobox domain-containing protein. (273 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1652 aa)
	cntn2	Contactin 2. (1034 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF4ENIF1	lsm1	ENSPREP00000003290	ENSPREP00000014089	Eukaryotic translation initiation factor 4E nuclear import factor 1.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.425
Six3	foxg1	ENSPREP00000004886	ENSPREP00000004343	SIX homeobox 3a.	Forkhead box G1a.	0.407
dlx1	dlx2	ENSPREP00000006380	ENSPREP00000006391	Distal-less homeobox 1a.	Distal-less homeobox 2b.	0.778
dlx2	dlx1	ENSPREP00000006391	ENSPREP00000006380	Distal-less homeobox 2b.	Distal-less homeobox 1a.	0.778
foxg1	Six3	ENSPREP00000004343	ENSPREP00000004886	Forkhead box G1a.	SIX homeobox 3a.	0.407
lsm1	EIF4ENIF1	ENSPREP00000014089	ENSPREP00000003290	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	Eukaryotic translation initiation factor 4E nuclear import factor 1.	0.425