(25 nodes) Positive regulation of mitotic nuclear division network (Poecilia reticulata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	edn1	Endothelin 1. (207 aa)
	LOC103477155	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (560 aa)
	Tgfa	Transforming growth factor, alpha. (166 aa)
	LOC103473479	EGF-like domain-containing protein. (217 aa)
	anapc11	APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
	cdc16	Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
	mad2l1bp	MAD2L1 binding protein. (372 aa)
	igf1	Insulin-like growth factor 1. (186 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (620 aa)
	LOC103469983	EGF-like domain-containing protein. (154 aa)
	LOC103469984	EGF-like domain-containing protein. (176 aa)
	cdc27	Cell division cycle 27. (803 aa)
	nsmce2	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (230 aa)
	LOC103470686	Interleukin-1. (247 aa)
	anapc7	Anaphase promoting complex subunit 7. (565 aa)
	LOC103479391	CULLIN_2 domain-containing protein; Belongs to the cullin family. (766 aa)
	ENSPREP00000027807	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (393 aa)
	LOC103474461	Cullin 3; Belongs to the cullin family. (767 aa)
	igf2	IlGF domain-containing protein. (223 aa)
	LOC103468546	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (220 aa)
	Rgcc	Regulator of cell cycle. (134 aa)
	anapc5	Anaphase promoting complex subunit 5. (773 aa)
	ENSPREP00000032744	Retinoblastoma 1. (864 aa)
	cdc23	CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (719 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000032744	LOC103474461	ENSPREP00000032744	ENSPREP00000027846	Retinoblastoma 1.	Cullin 3; Belongs to the cullin family.	0.538
ENSPREP00000032744	LOC103479391	ENSPREP00000032744	ENSPREP00000024968	Retinoblastoma 1.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.538
ENSPREP00000032744	anapc11	ENSPREP00000032744	ENSPREP00000004954	Retinoblastoma 1.	APC11 anaphase promoting complex subunit 11 homolog (yeast).	0.637
ENSPREP00000032744	cdc16	ENSPREP00000032744	ENSPREP00000008226	Retinoblastoma 1.	Cell division cycle 16 homolog (S. cerevisiae).	0.702
ENSPREP00000032744	cdc27	ENSPREP00000032744	ENSPREP00000018474	Retinoblastoma 1.	Cell division cycle 27.	0.687
ENSPREP00000032744	cdt1	ENSPREP00000032744	ENSPREP00000011428	Retinoblastoma 1.	Chromatin licensing and DNA replication factor 1.	0.595
LOC103469983	LOC103469984	ENSPREP00000013728	ENSPREP00000013758	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.782
LOC103469983	LOC103473479	ENSPREP00000013728	ENSPREP00000004655	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.816
LOC103469983	Tgfa	ENSPREP00000013728	ENSPREP00000003483	EGF-like domain-containing protein.	Transforming growth factor, alpha.	0.734
LOC103469984	LOC103469983	ENSPREP00000013758	ENSPREP00000013728	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.782
LOC103469984	LOC103473479	ENSPREP00000013758	ENSPREP00000004655	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.825
LOC103469984	Tgfa	ENSPREP00000013758	ENSPREP00000003483	EGF-like domain-containing protein.	Transforming growth factor, alpha.	0.743
LOC103470686	edn1	ENSPREP00000019387	ENSPREP00000012837	Interleukin-1.	Endothelin 1.	0.473
LOC103470686	igf1	ENSPREP00000019387	ENSPREP00000010429	Interleukin-1.	Insulin-like growth factor 1.	0.485
LOC103473479	LOC103469983	ENSPREP00000004655	ENSPREP00000013728	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.816
LOC103473479	LOC103469984	ENSPREP00000004655	ENSPREP00000013758	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.825
LOC103473479	Tgfa	ENSPREP00000004655	ENSPREP00000003483	EGF-like domain-containing protein.	Transforming growth factor, alpha.	0.594
LOC103474461	ENSPREP00000032744	ENSPREP00000027846	ENSPREP00000032744	Cullin 3; Belongs to the cullin family.	Retinoblastoma 1.	0.538
LOC103474461	LOC103479391	ENSPREP00000027846	ENSPREP00000024968	Cullin 3; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.900
LOC103474461	cdt1	ENSPREP00000027846	ENSPREP00000011428	Cullin 3; Belongs to the cullin family.	Chromatin licensing and DNA replication factor 1.	0.442