STRINGSTRING
mtnr1a mtnr1a LOC103477731 LOC103477731 LOC103464091 LOC103464091 LOC103464609 LOC103464609 LOC103464602 LOC103464602 htr7 htr7 drd4 drd4 ncor2 ncor2 LOC103463886 LOC103463886 ccdc90b ccdc90b LOC103477707 LOC103477707 arntl arntl sgpl1 sgpl1 sirt1 sirt1 LOC103477101 LOC103477101 GPR149 GPR149 LOC103470410 LOC103470410 LOC103459880 LOC103459880 ENSPREP00000004470 ENSPREP00000004470 LOC103479643 LOC103479643 per3 per3 naglu naglu LOC103471253 LOC103471253 adnp adnp egr1 egr1 Nfil3 Nfil3 ddb1 ddb1 LOC103466705 LOC103466705 GRIN3A GRIN3A ENSPREP00000008810 ENSPREP00000008810 PPARG PPARG egr3 egr3 atg7 atg7 kat2b kat2b ncor1 ncor1 LOC103470511 LOC103470511 ppp1cb ppp1cb noct noct fbxl3 fbxl3 Mycbp2 Mycbp2 ENSPREP00000010244 ENSPREP00000010244 ogt ogt dtl dtl crebbp crebbp LOC103468705 LOC103468705 LOC103476389 LOC103476389 sp1 sp1 cdk5 cdk5 sfpq sfpq kdm8 kdm8 dbp dbp scaper scaper DNM1L DNM1L CRTC1 CRTC1 kiaa2013 kiaa2013 LOC103463643 LOC103463643 nr0b2 nr0b2 ZNF830 ZNF830 LOC103462600 LOC103462600 LOC103469983 LOC103469983 rorb rorb ppara ppara LOC103466703 LOC103466703 EZH1 EZH1 lg2h3orf70 lg2h3orf70 LOC103479167 LOC103479167 LOC103463403 LOC103463403 ENSPREP00000014132 ENSPREP00000014132 LOC103463612 LOC103463612 ngfr ngfr LOC103459482 LOC103459482 Nono Nono gpr176 gpr176 cipc cipc nrip1 nrip1 LOC103468963 LOC103468963 ezh2 ezh2 ENSPREP00000016378 ENSPREP00000016378 Mtor Mtor PER2 PER2 LOC103465907 LOC103465907 PPARA PPARA nampt nampt LOC103460198 LOC103460198 LOC103480497 LOC103480497 LOC103468951 LOC103468951 LOC103469458 LOC103469458 hlf hlf impdh2 impdh2 ENSPREP00000019401 ENSPREP00000019401 LOC103479274 LOC103479274 pam pam LOC103468340 LOC103468340 LOC103468341 LOC103468341 LOC103471958 LOC103471958 gas2 gas2 LOC103474297 LOC103474297 LOC103475521 LOC103475521 LOC103471983 LOC103471983 timeless timeless nfya nfya LOC103465341 LOC103465341 gpr157 gpr157 ARNTL2 ARNTL2 tnfrsf11a tnfrsf11a plekha1 plekha1 LOC103468403 LOC103468403 LOC103457896 LOC103457896 BHLHE40 BHLHE40 LOC103482332 LOC103482332 LOC103482321 LOC103482321 LOC103481883 LOC103481883 ppp1cc ppp1cc LOC103463031 LOC103463031 mybbp1a mybbp1a ptx3 ptx3 LOC103481034 LOC103481034 LOC103468446 LOC103468446 LOC103478733 LOC103478733 LOC103479463 LOC103479463 tnfaip6 tnfaip6 LOC103466090 LOC103466090 LOC103468460 LOC103468460 ncoa2 ncoa2 bhlhe41 bhlhe41 Top1 Top1 btbd9 btbd9 mapk10 mapk10 nudt12 nudt12 ENSPREP00000027951 ENSPREP00000027951 LOC103472681 LOC103472681 HOMER1 HOMER1 ppargc1a ppargc1a dhx9 dhx9 LOC103458857 LOC103458857 LOC103469724 LOC103469724 piwil2 piwil2 LOC103466760 LOC103466760 CLOCK CLOCK AANAT AANAT LOC103481169 LOC103481169 ndufa9 ndufa9 LOC103461922 LOC103461922 LOC103465472 LOC103465472 LOC103467373 LOC103467373 fzd4 fzd4 ENSPREP00000030584 ENSPREP00000030584 LOC103482005 LOC103482005 LOC103475715 LOC103475715 prkaa2 prkaa2 LOC103476945 LOC103476945 LOC103465515 LOC103465515 LOC103461978 LOC103461978 LOC103457262 LOC103457262 mapk8 mapk8 LOC103457584 LOC103457584 prkaa1 prkaa1 huwe1 huwe1 PPP1CB PPP1CB prmt5 prmt5 LOC103470963 LOC103470963 ENSPREP00000032886 ENSPREP00000032886 ptn ptn LOC103465574 LOC103465574 lgr4 lgr4 LOC103475806 LOC103475806 LOC103481795 LOC103481795 LOC103481373 LOC103481373
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mtnr1aMelatonin receptor 1A a; Belongs to the G-protein coupled receptor 1 family. (380 aa)
LOC103477731Activating transcription factor 4a. (424 aa)
LOC103464091CREB binding protein a. (2371 aa)
LOC103464609BZIP domain-containing protein. (373 aa)
LOC103464602Nuclear factor, interleukin 3 regulated, member 5. (616 aa)
htr75-hydroxytryptamine (serotonin) receptor 7a; Belongs to the G-protein coupled receptor 1 family. (414 aa)
drd4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (406 aa)
ncor2Nuclear receptor corepressor 2. (2291 aa)
LOC103463886Nocturnin. (385 aa)
ccdc90bCoiled-coil domain containing 90B. (238 aa)
LOC103477707Nuclear receptor subfamily 1, group D, member 2a. (544 aa)
arntlAryl hydrocarbon receptor nuclear translocator-like 1a. (602 aa)
sgpl1Sphingosine-1-phosphate lyase 1. (565 aa)
sirt1Sirtuin 1. (677 aa)
LOC103477101Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (536 aa)
GPR149G protein-coupled receptor 149. (766 aa)
LOC103470410Homer scaffold protein 1b. (402 aa)
LOC103459880E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (387 aa)
ENSPREP00000004470Uncharacterized protein. (64 aa)
LOC103479643Period circadian clock 2. (1451 aa)
per3Period circadian clock 3. (1280 aa)
nagluN-acetylglucosaminidase, alpha. (796 aa)
LOC103471253Mitogen-activated protein kinase. (420 aa)
adnpActivity-dependent neuroprotector homeobox b. (1057 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (511 aa)
Nfil3Nuclear factor, interleukin 3 regulated. (393 aa)
ddb1Damage-specific DNA binding protein 1. (1102 aa)
LOC103466705Si:ch1073-390k14.1. (634 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1152 aa)
ENSPREP00000008810Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (962 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (474 aa)
egr3Early growth response 3. (410 aa)
atg7ATG7 autophagy related 7 homolog (S. cerevisiae). (720 aa)
kat2bHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (798 aa)
ncor1Nuclear receptor corepressor 1. (2343 aa)
LOC103470511Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (673 aa)
ppp1cbSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
noctNocturnin. (445 aa)
fbxl3F-box and leucine-rich repeat protein 3a. (435 aa)
Mycbp2RING-type domain-containing protein. (497 aa)
ENSPREP00000010244Uncharacterized protein. (446 aa)
ogtO-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1039 aa)
dtlDenticleless E3 ubiquitin protein ligase homolog (Drosophila). (704 aa)
crebbpCREB binding protein b. (2452 aa)
LOC103468705Arylalkylamine N-acetyltransferase 2. (222 aa)
LOC103476389Paraspeckle component 1. (517 aa)
sp1Sp1 transcription factor. (593 aa)
cdk5Cyclin-dependent kinase 5. (262 aa)
sfpqSplicing factor proline/glutamine-rich. (709 aa)
kdm8Lysine (K)-specific demethylase 8. (471 aa)
dbpD site albumin promoter binding protein b. (372 aa)
scaperS-phase cyclin A-associated protein in the ER. (1468 aa)
DNM1LDynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (731 aa)
CRTC1CREB regulated transcription coactivator 1b. (688 aa)
kiaa2013Si:dkeyp-104h9.5. (620 aa)
LOC103463643Nuclear factor, interleukin 3 regulated, member 4. (245 aa)
nr0b2Nuclear receptor subfamily 0, group B, member 2a. (260 aa)
ZNF830Zinc finger protein 830. (333 aa)
LOC103462600Cryptochrome circadian regulator 5. (521 aa)
LOC103469983EGF-like domain-containing protein. (154 aa)
rorbRAR-related orphan receptor B. (479 aa)
pparaPeroxisome proliferator-activated receptor alpha a. (472 aa)
LOC103466703Uncharacterized protein. (269 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (770 aa)
lg2h3orf70Zgc:162707. (284 aa)
LOC103479167CREB regulated transcription coactivator 1a. (518 aa)
LOC103463403Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1126 aa)
ENSPREP00000014132Uncharacterized protein. (138 aa)
LOC103463612RAR-related orphan receptor C a. (475 aa)
ngfrNerve growth factor receptor a (TNFR superfamily, member 16). (313 aa)
LOC103459482Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (661 aa)
NonoNon-POU domain containing, octamer-binding. (443 aa)
gpr176G protein-coupled receptor 176. (511 aa)
cipcCLOCK-interacting pacemaker a. (358 aa)
nrip1Nuclear receptor interacting protein 1b. (1200 aa)
LOC103468963Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (334 aa)
ezh2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (762 aa)
ENSPREP00000016378Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (702 aa)
MtorSerine/threonine-protein kinase TOR. (1001 aa)
PER2Period circadian regulator 2. (1494 aa)
LOC103465907Inhibitor of DNA binding 4. (150 aa)
PPARAPeroxisome proliferator-activated receptor alpha b. (469 aa)
namptNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (505 aa)
LOC103460198RRM domain-containing protein. (631 aa)
LOC103480497Period circadian clock 1b. (1441 aa)
LOC103468951Uncharacterized protein. (908 aa)
LOC103469458Nuclear receptor subfamily 1, group d, member 1. (523 aa)
hlfBZIP domain-containing protein. (295 aa)
impdh2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (521 aa)
ENSPREP00000019401Ecto-NOX disulfide-thiol exchanger 2. (356 aa)
LOC103479274RAR-related orphan receptor C b. (500 aa)
pamPeptidylglycine alpha-amidating monooxygenase. (947 aa)
LOC103468340Nuclear factor, interleukin 3 regulated, member 6. (392 aa)
LOC103468341BZIP domain-containing protein. (596 aa)
LOC103471958Nuclear receptor subfamily 1, group D, member 2b. (583 aa)
gas2Growth arrest-specific 2a. (306 aa)
LOC103474297Activating transcription factor 5b. (470 aa)
LOC103475521Melatonin receptor 1Bb; Belongs to the G-protein coupled receptor 1 family. (360 aa)
LOC103471983Endothelin 2. (172 aa)
timelessTimeless circadian clock. (1173 aa)
nfyaNuclear transcription factor Y, alpha, like. (327 aa)
LOC103465341Nuclear receptor subfamily 1, group D, member 4b. (573 aa)
gpr157G protein-coupled receptor 157. (336 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (527 aa)
tnfrsf11aTumor necrosis factor receptor superfamily, member 11a, NFKB activator. (567 aa)
plekha1Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (333 aa)
LOC103468403N-acetyltransferase domain-containing protein. (226 aa)
LOC103457896CLOCK-interacting pacemaker b. (390 aa)
BHLHE40Basic helix-loop-helix family member e40. (428 aa)
LOC103482332Uncharacterized protein. (963 aa)
LOC103482321Uncharacterized protein. (947 aa)
LOC103481883HLF transcription factor, PAR bZIP family member b. (298 aa)
ppp1ccSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (342 aa)
LOC103463031Dopamine receptor D4a. (359 aa)
mybbp1aMYB binding protein (P160) 1a. (1240 aa)
ptx3Pentraxin 3, long b. (445 aa)
LOC103481034Casein kinase 1, epsilon; Belongs to the protein kinase superfamily. (401 aa)
LOC103468446Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa)
LOC103478733Uncharacterized protein. (483 aa)
LOC103479463Sirtuin 6. (339 aa)
tnfaip6Tumor necrosis factor, alpha-induced protein 6. (239 aa)
LOC103466090Aryl hydrocarbon receptor nuclear translocator-like 2. (636 aa)
LOC103468460E1A binding protein p300 b. (2737 aa)
ncoa2Nuclear receptor coactivator 2. (1521 aa)
bhlhe41Basic helix-loop-helix family, member e41. (421 aa)
Top1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (606 aa)
btbd9BTB (POZ) domain containing 9. (613 aa)
mapk10Mitogen-activated protein kinase. (426 aa)
nudt12Nudix (nucleoside diphosphate linked moiety X)-type motif 12. (462 aa)
ENSPREP00000027951Uncharacterized protein. (379 aa)
LOC103472681Circadian associated repressor of transcription a. (317 aa)
HOMER1Homer scaffold protein 1. (377 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1284 aa)
dhx9DEAH (Asp-Glu-Ala-His) box helicase 9. (1216 aa)
LOC103458857Inhibitor of DNA binding 3. (116 aa)
LOC1034697245-hydroxytryptamine (serotonin) receptor 7b. (409 aa)
piwil2Piwi-like RNA-mediated gene silencing 2; Belongs to the argonaute family. (1055 aa)
LOC103466760Cryptochrome circadian regulator 2. (502 aa)
CLOCKClock circadian regulator a. (833 aa)
AANATArylalkylamine N-acetyltransferase 1. (198 aa)
LOC103481169DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (597 aa)
ndufa9NADH:ubiquinone oxidoreductase subunit A9a. (382 aa)
LOC103461922Photolyase/cryptochrome alpha/beta domain-containing protein. (652 aa)
LOC103465472Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (494 aa)
LOC103467373Nuclear receptor subfamily 1, group D, member 4a. (585 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
ENSPREP00000030584Cytochrome P450, family 1, subfamily C, polypeptide 2. (479 aa)
LOC103482005E1A binding protein p300 a. (2743 aa)
LOC103475715Neuronal PAS domain protein 2. (855 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
LOC103476945Mitogen-activated protein kinase. (360 aa)
LOC103465515Basic helix-loop-helix family, member e40. (408 aa)
LOC103461978F-box domain-containing protein. (451 aa)
LOC103457262Aryl hydrocarbon receptor 1b. (810 aa)
mapk8Mitogen-activated protein kinase. (426 aa)
LOC103457584Aryl hydrocarbon receptor 2. (750 aa)
prkaa1Non-specific serine/threonine protein kinase. (637 aa)
huwe1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4580 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
prmt5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (699 aa)
LOC103470963Hairy-related 11. (276 aa)
ENSPREP00000032886DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (573 aa)
ptnPleiotrophin. (161 aa)
LOC103465574Inhibitor of DNA binding 1, HLH protein. (127 aa)
lgr4Leucine-rich repeat containing G protein-coupled receptor 4. (913 aa)
LOC103475806Activating transcription factor 5a. (505 aa)
LOC103481795Nerve growth factor receptor b. (354 aa)
LOC103481373Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (325 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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