(31 nodes) Embryonic camera-type eye morphogenesis network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000028482	Uncharacterized protein. (587 aa)
	LOC103476521	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	LOC103476847	Paired box 2a. (322 aa)
	rax	Retinal homeobox gene 3. (310 aa)
	vax1	Ventral anterior homeobox 1. (285 aa)
	ENSPREP00000025759	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
	efnb2	Ephrin-B2a; Belongs to the ephrin family. (313 aa)
	mab21l2	Mab-21-like 2. (359 aa)
	LOC103481447	Paired box 2b. (392 aa)
	LOC103475931	SIX homeobox 7. (260 aa)
	Six3	SIX homeobox 3a. (341 aa)
	ENSPREP00000005246	Protein kinase domain-containing protein. (250 aa)
	vax2	Ventral anterior homeobox 2. (304 aa)
	LOC103481539	SIX homeobox 3b. (277 aa)
	SP3	Sp3a transcription factor. (699 aa)
	LOC103458727	Sp3b transcription factor. (680 aa)
	LOC103479553	Phosphatase and actin regulator. (548 aa)
	pax5	Paired box 5. (396 aa)
	LOC103478449	Phosphatase and actin regulator. (879 aa)
	LOC103463401	Phosphatase and actin regulator. (570 aa)
	pitx2	Homeobox protein. (312 aa)
	epha4	Eph receptor A4, like. (979 aa)
	Mab21l1	Mab-21 domain-containing protein. (140 aa)
	LOC103479267	Uncharacterized protein. (1084 aa)
	LOC103471985	Phosphatase and actin regulator 4a. (1141 aa)
	LOC103482434	Forkhead box H1. (633 aa)
	pax8	Paired box 8. (495 aa)
	six6	SIX homeobox 6a. (245 aa)
	ENSPREP00000025214	Paired domain-containing protein. (156 aa)
	Mib1	Mindbomb E3 ubiquitin protein ligase 1. (994 aa)
	LOC103469771	Zinc finger protein 703. (579 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000005246	efnb2	ENSPREP00000005246	ENSPREP00000028109	Protein kinase domain-containing protein.	Ephrin-B2a; Belongs to the ephrin family.	0.574
ENSPREP00000025214	LOC103475931	ENSPREP00000025214	ENSPREP00000004379	Paired domain-containing protein.	SIX homeobox 7.	0.452
ENSPREP00000025214	LOC103481539	ENSPREP00000025214	ENSPREP00000007219	Paired domain-containing protein.	SIX homeobox 3b.	0.434
LOC103475931	ENSPREP00000025214	ENSPREP00000004379	ENSPREP00000025214	SIX homeobox 7.	Paired domain-containing protein.	0.452
LOC103475931	pitx2	ENSPREP00000004379	ENSPREP00000015332	SIX homeobox 7.	Homeobox protein.	0.478
LOC103476847	vax1	ENSPREP00000025883	ENSPREP00000027397	Paired box 2a.	Ventral anterior homeobox 1.	0.672
LOC103479267	efnb2	ENSPREP00000019054	ENSPREP00000028109	Uncharacterized protein.	Ephrin-B2a; Belongs to the ephrin family.	0.574
LOC103481539	ENSPREP00000025214	ENSPREP00000007219	ENSPREP00000025214	SIX homeobox 3b.	Paired domain-containing protein.	0.434
LOC103481539	rax	ENSPREP00000007219	ENSPREP00000026650	SIX homeobox 3b.	Retinal homeobox gene 3.	0.532
Six3	rax	ENSPREP00000004886	ENSPREP00000026650	SIX homeobox 3a.	Retinal homeobox gene 3.	0.550
efnb2	ENSPREP00000005246	ENSPREP00000028109	ENSPREP00000005246	Ephrin-B2a; Belongs to the ephrin family.	Protein kinase domain-containing protein.	0.574
efnb2	LOC103479267	ENSPREP00000028109	ENSPREP00000019054	Ephrin-B2a; Belongs to the ephrin family.	Uncharacterized protein.	0.574
efnb2	epha4	ENSPREP00000028109	ENSPREP00000015956	Ephrin-B2a; Belongs to the ephrin family.	Eph receptor A4, like.	0.574
epha4	efnb2	ENSPREP00000015956	ENSPREP00000028109	Eph receptor A4, like.	Ephrin-B2a; Belongs to the ephrin family.	0.574
pitx2	LOC103475931	ENSPREP00000015332	ENSPREP00000004379	Homeobox protein.	SIX homeobox 7.	0.478
rax	LOC103481539	ENSPREP00000026650	ENSPREP00000007219	Retinal homeobox gene 3.	SIX homeobox 3b.	0.532
rax	Six3	ENSPREP00000026650	ENSPREP00000004886	Retinal homeobox gene 3.	SIX homeobox 3a.	0.550
vax1	LOC103476847	ENSPREP00000027397	ENSPREP00000025883	Ventral anterior homeobox 1.	Paired box 2a.	0.672