(21 nodes) Brain morphogenesis network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	slc6a4	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (714 aa)
	bbs1	Bardet-Biedl syndrome 1. (583 aa)
	LOC103482193	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (506 aa)
	LOC103471147	Catenin (cadherin-associated protein), alpha 1. (847 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)
	bbs4	Bardet-Biedl syndrome 4. (520 aa)
	LOC103470329	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (568 aa)
	LOC103473396	Laminin, gamma 3. (1298 aa)
	ENSPREP00000031011	CDP-L-ribitol pyrophosphorylase A. (321 aa)
	gsx2	GS homeobox 2. (239 aa)
	ENSPREP00000028495	Uncharacterized protein. (149 aa)
	lamc1	Laminin, gamma 1. (1610 aa)
	LOC103476999	Homeobox domain-containing protein. (153 aa)
	fancc	FA complementation group C. (596 aa)
	LOC103482434	Forkhead box H1. (633 aa)
	znf335	Zinc finger protein 335. (1142 aa)
	nf1	Neurofibromin 1b. (2742 aa)
	uchl5	Ubiquitin carboxyl-terminal hydrolase. (339 aa)
	fancd2	FA complementation group D2. (1432 aa)
	ctnna2	Catenin (cadherin-associated protein), alpha 2. (933 aa)
	mkks	McKusick-Kaufman syndrome. (576 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000028495	LOC103471147	ENSPREP00000028495	ENSPREP00000009514	Uncharacterized protein.	Catenin (cadherin-associated protein), alpha 1.	0.928
LOC103471147	ENSPREP00000028495	ENSPREP00000009514	ENSPREP00000028495	Catenin (cadherin-associated protein), alpha 1.	Uncharacterized protein.	0.928
bbs1	bbs4	ENSPREP00000001676	ENSPREP00000009421	Bardet-Biedl syndrome 1.	Bardet-Biedl syndrome 4.	0.991
bbs1	mkks	ENSPREP00000001676	ENSPREP00000010575	Bardet-Biedl syndrome 1.	McKusick-Kaufman syndrome.	0.433
bbs1	smo	ENSPREP00000001676	ENSPREP00000005932	Bardet-Biedl syndrome 1.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.809
bbs4	bbs1	ENSPREP00000009421	ENSPREP00000001676	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1.	0.991
bbs4	smo	ENSPREP00000009421	ENSPREP00000005932	Bardet-Biedl syndrome 4.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.687
fancc	fancd2	ENSPREP00000025078	ENSPREP00000014095	FA complementation group C.	FA complementation group D2.	0.997
fancd2	fancc	ENSPREP00000014095	ENSPREP00000025078	FA complementation group D2.	FA complementation group C.	0.997
mkks	bbs1	ENSPREP00000010575	ENSPREP00000001676	McKusick-Kaufman syndrome.	Bardet-Biedl syndrome 1.	0.433
smo	bbs1	ENSPREP00000005932	ENSPREP00000001676	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Bardet-Biedl syndrome 1.	0.809
smo	bbs4	ENSPREP00000005932	ENSPREP00000009421	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Bardet-Biedl syndrome 4.	0.687