(22 nodes) Neural nucleus development network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Srrm4	Serine/arginine repetitive matrix 4. (417 aa)
	bmp2	Bone morphogenetic protein 2b. (419 aa)
	ENSPREP00000023272	Uncharacterized protein. (267 aa)
	pax8	Paired box 8. (495 aa)
	prkci	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (557 aa)
	cdk5r1	Cyclin-dependent kinase 5 activator. (450 aa)
	LOC103468291	Cyclin-dependent kinase 5 activator. (334 aa)
	rest	RE1-silencing transcription factor. (902 aa)
	MAFB	MAF bZIP transcription factor B. (410 aa)
	LOC103460864	Uncharacterized protein; Belongs to the MAGUK family. (538 aa)
	ENSPREP00000013704	Uncharacterized protein. (155 aa)
	LOC103473007	Cyclin-dependent kinase 5 activator. (321 aa)
	mpp5	Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (650 aa)
	phox2b	Paired like homeobox 2Bb. (285 aa)
	pax5	Paired box 5. (396 aa)
	ENSPREP00000024223	Uncharacterized protein. (147 aa)
	LOC103481447	Paired box 2b. (392 aa)
	ENSPREP00000025214	Paired domain-containing protein. (156 aa)
	LOC103476847	Paired box 2a. (322 aa)
	phox2a	Paired like homeobox 2A. (301 aa)
	LOC103476521	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (236 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000013704	LOC103460864	ENSPREP00000013704	ENSPREP00000013760	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.854
ENSPREP00000023272	LOC103468291	ENSPREP00000023272	ENSPREP00000017469	Uncharacterized protein.	Cyclin-dependent kinase 5 activator.	0.418
ENSPREP00000023272	LOC103473007	ENSPREP00000023272	ENSPREP00000012825	Uncharacterized protein.	Cyclin-dependent kinase 5 activator.	0.422
ENSPREP00000023272	cdk5r1	ENSPREP00000023272	ENSPREP00000018796	Uncharacterized protein.	Cyclin-dependent kinase 5 activator.	0.412
LOC103460864	ENSPREP00000013704	ENSPREP00000013760	ENSPREP00000013704	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein.	0.854
LOC103460864	mpp5	ENSPREP00000013760	ENSPREP00000012779	Uncharacterized protein; Belongs to the MAGUK family.	Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.	0.902
LOC103468291	ENSPREP00000023272	ENSPREP00000017469	ENSPREP00000023272	Cyclin-dependent kinase 5 activator.	Uncharacterized protein.	0.418
LOC103473007	ENSPREP00000023272	ENSPREP00000012825	ENSPREP00000023272	Cyclin-dependent kinase 5 activator.	Uncharacterized protein.	0.422
LOC103476521	fgf3	ENSPREP00000029747	ENSPREP00000002583	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.795
cdk5r1	ENSPREP00000023272	ENSPREP00000018796	ENSPREP00000023272	Cyclin-dependent kinase 5 activator.	Uncharacterized protein.	0.412
fgf3	LOC103476521	ENSPREP00000002583	ENSPREP00000029747	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.795
mpp5	LOC103460864	ENSPREP00000012779	ENSPREP00000013760	Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.	Uncharacterized protein; Belongs to the MAGUK family.	0.902