(13 nodes) Posterior lateral line development network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Mib1	Mindbomb E3 ubiquitin protein ligase 1. (994 aa)
	LOC103469672	Fibroblast growth factor receptor. (831 aa)
	llgl2	LLGL scribble cell polarity complex component 2. (1006 aa)
	LOC103471035	Mothers against decapentaplegic homolog. (475 aa)
	znrf3	Zinc and ring finger 3. (891 aa)
	neurod1	Neurogenic differentiation factor. (353 aa)
	LOC103464516	Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (236 aa)
	gnb1	Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (340 aa)
	LOC103478337	R-spondin 3. (325 aa)
	abhd12	Abhydrolase domain containing 12. (289 aa)
	tmem132e	Transmembrane protein 132E. (1031 aa)
	yap1	Yes-associated protein 1. (433 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464516	gnb1	ENSPREP00000006363	ENSPREP00000015702	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	Guanine nucleotide binding protein (G protein), beta polypeptide 1a.	0.900
LOC103469672	fgf3	ENSPREP00000001007	ENSPREP00000002583	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.858
LOC103471035	yap1	ENSPREP00000005305	ENSPREP00000022087	Mothers against decapentaplegic homolog.	Yes-associated protein 1.	0.652
LOC103478337	znrf3	ENSPREP00000019049	ENSPREP00000006299	R-spondin 3.	Zinc and ring finger 3.	0.980
fgf3	LOC103469672	ENSPREP00000002583	ENSPREP00000001007	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.858
gnb1	LOC103464516	ENSPREP00000015702	ENSPREP00000006363	Guanine nucleotide binding protein (G protein), beta polypeptide 1a.	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	0.900
yap1	LOC103471035	ENSPREP00000022087	ENSPREP00000005305	Yes-associated protein 1.	Mothers against decapentaplegic homolog.	0.652
znrf3	LOC103478337	ENSPREP00000006299	ENSPREP00000019049	Zinc and ring finger 3.	R-spondin 3.	0.980