(67 nodes) Positive regulation of inflammatory response network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000002319	Uncharacterized protein. (463 aa)
	LOC103474681	Uncharacterized protein; Belongs to the peptidase C14A family. (386 aa)
	ENSPREP00000002720	Uncharacterized protein. (221 aa)
	ENSPREP00000002978	Uncharacterized protein. (84 aa)
	ENSPREP00000003810	Uncharacterized protein. (206 aa)
	LOC103477730	Uncharacterized protein. (193 aa)
	ENSPREP00000003888	Uncharacterized protein; Belongs to the peptidase C14A family. (334 aa)
	LOC103480133	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (390 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2573 aa)
	ENSPREP00000006306	Uncharacterized protein. (79 aa)
	LOC103471087	Uncharacterized protein. (879 aa)
	LOC103459310	N-acyl phosphatidylethanolamine phospholipase D. (268 aa)
	LOC103466391	Programmed cell death 4a. (434 aa)
	setd4	SET domain containing 4. (399 aa)
	tnip1	TNFAIP3 interacting protein 1. (582 aa)
	LOC103477767	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (345 aa)
	ENSPREP00000010056	G_PROTEIN_RECEP_F1_2 domain-containing protein. (300 aa)
	ENSPREP00000010067	Si:ch211-231m23.4. (304 aa)
	LOC103469200	G protein-coupled receptor, class C, group 5, member Ba. (397 aa)
	LOC103465116	Ninjurin 1. (142 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (315 aa)
	ENSPREP00000012157	SEFIR domain-containing protein. (496 aa)
	ENSPREP00000012469	Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (487 aa)
	LOC103466593	C2 calcium dependent domain containing 4A. (448 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2b. (615 aa)
	ENSPREP00000013396	Si:dkey-211g8.6. (312 aa)
	LOC103460866	G_PROTEIN_RECEP_F1_2 domain-containing protein. (272 aa)
	ENSPREP00000014253	Uncharacterized protein. (149 aa)
	LOC103476935	ZP domain-containing protein. (392 aa)
	LOC103461636	Sorting nexin 4. (455 aa)
	tnfrsf1a	Tumor necrosis factor receptor superfamily, member 1a. (333 aa)
	ifi35	Interferon-induced protein 35. (384 aa)
	LOC108165882	Uncharacterized protein. (74 aa)
	C2CD4C	C2 calcium dependent domain containing 4C. (419 aa)
	LOC103479269	C2 domain-containing protein. (427 aa)
	LOC103470686	Interleukin-1. (247 aa)
	LOC103466036	ZP domain-containing protein. (423 aa)
	ENSPREP00000022389	Prostaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (424 aa)
	LOC103482515	Uncharacterized protein. (370 aa)
	ENSPREP00000022754	Vesicle-associated membrane protein 8 (endobrevin). (118 aa)
	ENSPREP00000022805	V-SNARE coiled-coil homology domain-containing protein. (116 aa)
	tnfrsf11a	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (567 aa)
	IL18	Uncharacterized protein. (218 aa)
	LOC103471376	Uncharacterized protein. (383 aa)
	LGALS2	Galectin. (140 aa)
	il17ra	SEFIR domain-containing protein. (839 aa)
	LOC103459747	PX domain-containing protein. (433 aa)
	LOC103457805	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (301 aa)
	LOC103477681	ANK_REP_REGION domain-containing protein. (435 aa)
	LOC103475146	G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (348 aa)
	tnfsf11	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (268 aa)
	ENSPREP00000030231	Uncharacterized protein. (800 aa)
	ENSPREP00000030263	Uncharacterized protein. (812 aa)
	ENSPREP00000030269	Uncharacterized protein. (785 aa)
	ctsc	Cathepsin C; Belongs to the peptidase C1 family. (453 aa)
	ENSPREP00000031766	Uncharacterized protein. (309 aa)
	ptger4	Prostaglandin E receptor 4 (subtype EP4) b. (456 aa)
	napepld	Lactamase_B domain-containing protein. (293 aa)
	il16	Uncharacterized protein. (619 aa)
	kars1	Lysine--tRNA ligase. (609 aa)
	ENSPREP00000002308	Uncharacterized protein; Belongs to the peptidase C14A family. (388 aa)
	ENSPREP00000002255	Uncharacterized protein; Belongs to the peptidase C14A family. (387 aa)
	LOC103467753	CCAAT enhancer binding protein beta. (285 aa)
	LOC103468616	Galectin. (176 aa)
	gprc5b	G protein-coupled receptor, class C, group 5, member Bb. (419 aa)
	pdcd4	Programmed cell death 4b. (494 aa)
	LOC103480204	Galectin. (126 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002255	ENSPREP00000003810	ENSPREP00000002255	ENSPREP00000003810	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.701
ENSPREP00000002255	LOC103470686	ENSPREP00000002255	ENSPREP00000019387	Uncharacterized protein; Belongs to the peptidase C14A family.	Interleukin-1.	0.733
ENSPREP00000002255	LOC103477730	ENSPREP00000002255	ENSPREP00000003858	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.701
ENSPREP00000002308	ENSPREP00000003810	ENSPREP00000002308	ENSPREP00000003810	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.701
ENSPREP00000002308	IL18	ENSPREP00000002308	ENSPREP00000023832	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.444
ENSPREP00000002308	LOC103470686	ENSPREP00000002308	ENSPREP00000019387	Uncharacterized protein; Belongs to the peptidase C14A family.	Interleukin-1.	0.733
ENSPREP00000002308	LOC103477730	ENSPREP00000002308	ENSPREP00000003858	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.751
ENSPREP00000002319	IL18	ENSPREP00000002319	ENSPREP00000023832	Uncharacterized protein.	Uncharacterized protein.	0.416
ENSPREP00000002319	LOC103470686	ENSPREP00000002319	ENSPREP00000019387	Uncharacterized protein.	Interleukin-1.	0.890
ENSPREP00000003810	ENSPREP00000002255	ENSPREP00000003810	ENSPREP00000002255	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.701
ENSPREP00000003810	ENSPREP00000002308	ENSPREP00000003810	ENSPREP00000002308	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.701
ENSPREP00000003810	ENSPREP00000003888	ENSPREP00000003810	ENSPREP00000003888	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.701
ENSPREP00000003810	ENSPREP00000030231	ENSPREP00000003810	ENSPREP00000030231	Uncharacterized protein.	Uncharacterized protein.	0.413
ENSPREP00000003810	ENSPREP00000030263	ENSPREP00000003810	ENSPREP00000030263	Uncharacterized protein.	Uncharacterized protein.	0.413
ENSPREP00000003810	ENSPREP00000030269	ENSPREP00000003810	ENSPREP00000030269	Uncharacterized protein.	Uncharacterized protein.	0.413
ENSPREP00000003810	IL18	ENSPREP00000003810	ENSPREP00000023832	Uncharacterized protein.	Uncharacterized protein.	0.440
ENSPREP00000003810	LOC103470686	ENSPREP00000003810	ENSPREP00000019387	Uncharacterized protein.	Interleukin-1.	0.675
ENSPREP00000003810	LOC103474681	ENSPREP00000003810	ENSPREP00000002342	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.701
ENSPREP00000003810	LOC103477730	ENSPREP00000003810	ENSPREP00000003858	Uncharacterized protein.	Uncharacterized protein.	0.571
ENSPREP00000003888	ENSPREP00000003810	ENSPREP00000003888	ENSPREP00000003810	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.701