(25 nodes) Neuromuscular process controlling balance network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103475259	Clarin 1. (200 aa)
	lrrc45	Leucine rich repeat containing 45. (674 aa)
	LOC103457483	Otoferlin a. (1904 aa)
	LOC103472429	Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino. (245 aa)
	LOC103466557	Beta-hexosaminidase. (532 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (834 aa)
	Shank1	SAM domain-containing protein. (1628 aa)
	abl1	Tyrosine-protein kinase. (1124 aa)
	LOC103466031	SH3 and multiple ankyrin repeat domains 3a. (1984 aa)
	Gm2a	GM2 ganglioside activator. (198 aa)
	otof	Otoferlin b. (1641 aa)
	LOC103477457	Uncharacterized protein. (674 aa)
	LOC103463007	SH3 and multiple ankyrin repeat domains 2a. (1709 aa)
	LOC103457071	Fer-1 like family member 6. (1480 aa)
	LOC103481054	Uncharacterized protein. (2065 aa)
	LOC103466091	Solute carrier family 17 member 8. (585 aa)
	abl2	Tyrosine-protein kinase. (1187 aa)
	LOC103472149	Uncharacterized protein. (663 aa)
	ush1c	Usher syndrome 1C. (553 aa)
	hexb	Beta-hexosaminidase. (546 aa)
	pou4f1	POU domain protein. (334 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	Igdcc3	Immunoglobulin superfamily, DCC subclass, member 3. (355 aa)
	ENSPREP00000033672	Immunoglobulin superfamily, DCC subclass, member 3. (451 aa)
	pou4f2	POU domain protein. (386 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000033672	Igdcc3	ENSPREP00000033672	ENSPREP00000033669	Immunoglobulin superfamily, DCC subclass, member 3.	Immunoglobulin superfamily, DCC subclass, member 3.	0.911
Gm2a	LOC103466557	ENSPREP00000022022	ENSPREP00000014928	GM2 ganglioside activator.	Beta-hexosaminidase.	0.727
Gm2a	cln8	ENSPREP00000022022	ENSPREP00000032780	GM2 ganglioside activator.	CLN8 transmembrane ER and ERGIC protein.	0.441
Gm2a	hexb	ENSPREP00000022022	ENSPREP00000031004	GM2 ganglioside activator.	Beta-hexosaminidase.	0.727
Igdcc3	ENSPREP00000033672	ENSPREP00000033669	ENSPREP00000033672	Immunoglobulin superfamily, DCC subclass, member 3.	Immunoglobulin superfamily, DCC subclass, member 3.	0.911
LOC103466557	Gm2a	ENSPREP00000014928	ENSPREP00000022022	Beta-hexosaminidase.	GM2 ganglioside activator.	0.727
LOC103475259	ush1c	ENSPREP00000032120	ENSPREP00000030327	Clarin 1.	Usher syndrome 1C.	0.606
Shank1	shank1	ENSPREP00000015974	ENSPREP00000015953	SAM domain-containing protein.	SH3 and multiple ankyrin repeat domains 1.	0.896
abl1	abl2	ENSPREP00000021197	ENSPREP00000026823	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.915
abl2	abl1	ENSPREP00000026823	ENSPREP00000021197	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.915
cln8	Gm2a	ENSPREP00000032780	ENSPREP00000022022	CLN8 transmembrane ER and ERGIC protein.	GM2 ganglioside activator.	0.441
hexb	Gm2a	ENSPREP00000031004	ENSPREP00000022022	Beta-hexosaminidase.	GM2 ganglioside activator.	0.727
shank1	Shank1	ENSPREP00000015953	ENSPREP00000015974	SH3 and multiple ankyrin repeat domains 1.	SAM domain-containing protein.	0.896
ush1c	LOC103475259	ENSPREP00000030327	ENSPREP00000032120	Usher syndrome 1C.	Clarin 1.	0.606