(28 nodes) Endocrine process network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AVPR1A	Arginine vasopressin receptor 1Aa. (411 aa)
	LOC103459542	Arginine vasopressin receptor 2, like. (304 aa)
	serpinf2	SERPIN domain-containing protein; Belongs to the serpin family. (477 aa)
	oxtr	Oxytocin receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (390 aa)
	edn1	Endothelin 1. (207 aa)
	ENSPREP00000010780	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (176 aa)
	aqp1	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (268 aa)
	kcnq1	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (631 aa)
	LOC103464554	Oxytocin receptor like; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (395 aa)
	LOC103459868	SERPIN domain-containing protein; Belongs to the serpin family. (416 aa)
	LOC103459074	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (424 aa)
	LOC103478941	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (467 aa)
	ENSPREP00000018388	G_PROTEIN_RECEP_F1_2 domain-containing protein. (354 aa)
	enpep	Aminopeptidase. (947 aa)
	LOC103471983	Endothelin 2. (172 aa)
	tmf1	TATA element modulatory factor 1. (1150 aa)
	ENSPREP00000028578	Ion_trans domain-containing protein; Belongs to the potassium channel family. (424 aa)
	ace	Angiotensin-converting enzyme. (1291 aa)
	LOC103467895	G_PROTEIN_RECEP_F1_2 domain-containing protein. (496 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
	LOC103465492	Uncharacterized protein. (154 aa)
	ENSPREP00000031602	Selenoprotein M. (117 aa)
	LOC103465520	Si:dkey-178o16.4. (354 aa)
	agtr1	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	ENSPREP00000032179	Arginine vasopressin receptor 1Ab; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (409 aa)
	LOC103470946	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (423 aa)
	avpr2	Arginine vasopressin receptor 2a, duplicate a. (497 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (452 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AVPR1A	ENSPREP00000032179	ENSPREP00000017630	ENSPREP00000032179	Arginine vasopressin receptor 1Aa.	Arginine vasopressin receptor 1Ab; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	0.944
AVPR1A	LOC103465492	ENSPREP00000017630	ENSPREP00000030717	Arginine vasopressin receptor 1Aa.	Uncharacterized protein.	0.510
AVPR1A	edn1	ENSPREP00000017630	ENSPREP00000012837	Arginine vasopressin receptor 1Aa.	Endothelin 1.	0.536
ENSPREP00000018388	LOC103465492	ENSPREP00000018388	ENSPREP00000030717	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.510
ENSPREP00000018388	edn1	ENSPREP00000018388	ENSPREP00000012837	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Endothelin 1.	0.536
ENSPREP00000032179	AVPR1A	ENSPREP00000032179	ENSPREP00000017630	Arginine vasopressin receptor 1Ab; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Arginine vasopressin receptor 1Aa.	0.944
ENSPREP00000032179	LOC103465492	ENSPREP00000032179	ENSPREP00000030717	Arginine vasopressin receptor 1Ab; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Uncharacterized protein.	0.510
ENSPREP00000032179	edn1	ENSPREP00000032179	ENSPREP00000012837	Arginine vasopressin receptor 1Ab; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Endothelin 1.	0.536
LOC103459074	LOC103465492	ENSPREP00000002951	ENSPREP00000030717	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.987
LOC103459074	LOC103470946	ENSPREP00000002951	ENSPREP00000032490	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.902
LOC103459074	LOC103471983	ENSPREP00000002951	ENSPREP00000021381	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	Endothelin 2.	0.544
LOC103459074	LOC103478941	ENSPREP00000002951	ENSPREP00000002847	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.902
LOC103459074	agt	ENSPREP00000002951	ENSPREP00000016816	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	Angiotensinogen; Belongs to the serpin family.	0.571
LOC103459074	agtr1	ENSPREP00000002951	ENSPREP00000032143	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family.	0.405
LOC103459074	edn1	ENSPREP00000002951	ENSPREP00000012837	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.994
LOC103459542	LOC103465492	ENSPREP00000016283	ENSPREP00000030717	Arginine vasopressin receptor 2, like.	Uncharacterized protein.	0.510
LOC103459542	edn1	ENSPREP00000016283	ENSPREP00000012837	Arginine vasopressin receptor 2, like.	Endothelin 1.	0.536
LOC103464554	LOC103465492	ENSPREP00000005189	ENSPREP00000030717	Oxytocin receptor like; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Uncharacterized protein.	0.510
LOC103464554	edn1	ENSPREP00000005189	ENSPREP00000012837	Oxytocin receptor like; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Endothelin 1.	0.536
LOC103464554	oxtr	ENSPREP00000005189	ENSPREP00000013830	Oxytocin receptor like; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Oxytocin receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	0.901