(15 nodes) Intestinal absorption network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	npc1	Niemann-Pick disease, type C1. (1277 aa)
	LOC103460557	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (562 aa)
	kcnq1	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (631 aa)
	fabp2	Fatty acid binding protein 2, intestinal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1341 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (490 aa)
	ENSPREP00000021963	LIM zinc-binding domain-containing protein. (129 aa)
	LOC103480658	FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	ugcg	UDP-glucose ceramide glucosyltransferase. (400 aa)
	ENSPREP00000028578	Ion_trans domain-containing protein; Belongs to the potassium channel family. (424 aa)
	lima1	LIM domain and actin binding 1a. (617 aa)
	ENSPREP00000031515	LIM zinc-binding domain-containing protein. (211 aa)
	ENSPREP00000031527	Uncharacterized protein. (1802 aa)
	LOC103473964	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (506 aa)
	LOC103475799	F11 receptor, tandem duplicate 1. (308 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103460557	LOC103473964	ENSPREP00000004169	ENSPREP00000031991	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.902
LOC103473964	LOC103460557	ENSPREP00000031991	ENSPREP00000004169	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.902
LOC103480658	fabp2	ENSPREP00000025178	ENSPREP00000007234	FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Fatty acid binding protein 2, intestinal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.901
fabp2	LOC103480658	ENSPREP00000007234	ENSPREP00000025178	Fatty acid binding protein 2, intestinal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.901