(95 nodes) Neuromuscular process network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tcap	Titin-cap (telethonin). (187 aa)
	LOC103462623	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b. (1385 aa)
	LOC103472853	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1973 aa)
	vti1a	Vesicle transport through interaction with t-SNAREs 1A. (224 aa)
	ENSPREP00000002079	CAP-ZIP_m domain-containing protein. (325 aa)
	LOC103478929	Si:ch73-71c20.5. (138 aa)
	LOC103465645	Troponin I2, fast skeletal type. (171 aa)
	ENSPREP00000002982	Troponin I2, fast skeletal type. (161 aa)
	LOC103465646	Troponin I2, fast skeletal type. (171 aa)
	LOC103468062	Troponin C type 1b (slow). (161 aa)
	LOC103470410	Homer scaffold protein 1b. (402 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	lrrc45	Leucine rich repeat containing 45. (674 aa)
	LOC103466898	Si:rp71-17i16.4. (216 aa)
	LOC103466900	Troponin C type 2 (fast). (173 aa)
	LOC103481546	GTP cyclohydrolase 2. (236 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1152 aa)
	LOC103457483	Otoferlin a. (1904 aa)
	LOC103466651	Synemin, intermediate filament protein; Belongs to the intermediate filament family. (1005 aa)
	Mycbp2	RING-type domain-containing protein. (497 aa)
	ENSPREP00000010244	Uncharacterized protein. (446 aa)
	dctn1	Dynactin 1b. (1243 aa)
	LOC103476270	R3H domain containing 1. (1029 aa)
	TNNC1	Troponin C type 1a (slow). (163 aa)
	gbx1	Gastrulation brain homeobox 1. (322 aa)
	LOC103465819	Troponin I4a. (177 aa)
	LOC103465820	Troponin I4b, tandem duplicate 2. (182 aa)
	LOC103465821	Uncharacterized protein. (183 aa)
	LOC103472429	Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino. (245 aa)
	r3hdm2	R3H domain containing 2. (1073 aa)
	LOC103465822	Troponin I4b, tandem duplicate 2. (178 aa)
	LOC103478060	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b. (1839 aa)
	LOC103481634	Uncharacterized protein. (1385 aa)
	GLRB	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (455 aa)
	LOC103466557	Beta-hexosaminidase. (532 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (834 aa)
	Shank1	SAM domain-containing protein. (1628 aa)
	STAC2	SH3 and cysteine rich domain 2. (431 aa)
	ENSPREP00000016378	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (702 aa)
	Mtor	Serine/threonine-protein kinase TOR. (1001 aa)
	ENSPREP00000017645	Uncharacterized protein. (191 aa)
	penk	Uncharacterized protein. (246 aa)
	LOC103464710	Troponin I type 1b (skeletal, slow). (170 aa)
	fxn	Frataxin. (213 aa)
	mecp2	Methyl CpG binding protein 2. (982 aa)
	LOC103468798	Glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b. (1596 aa)
	LOC103474976	Spartin b. (598 aa)
	LOC103469050	Glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca. (1414 aa)
	ENSPREP00000020277	RBR-type E3 ubiquitin transferase. (158 aa)
	abl1	Tyrosine-protein kinase. (1124 aa)
	LOC103460857	PNKD metallo-beta-lactamase domain containing. (360 aa)
	LOC103480555	Dynactin 1a. (1280 aa)
	rcsd1	Zgc:153184. (284 aa)
	LOC103466031	SH3 and multiple ankyrin repeat domains 3a. (1984 aa)
	Gm2a	GM2 ganglioside activator. (198 aa)
	slitrk6	SLIT and NTRK-like family, member 6. (820 aa)
	otof	Otoferlin b. (1641 aa)
	LOC103477457	Uncharacterized protein. (674 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (619 aa)
	LOC103463007	SH3 and multiple ankyrin repeat domains 2a. (1709 aa)
	get1	Guided entry of tail-anchored proteins factor 1. (170 aa)
	grin2b	Uncharacterized protein. (1706 aa)
	LOC103457071	Fer-1 like family member 6. (1480 aa)
	LOC103481054	Uncharacterized protein. (2065 aa)
	opa3	Outer mitochondrial membrane lipid metabolism regulator OPA3. (156 aa)
	LOC103466091	Solute carrier family 17 member 8. (585 aa)
	ENSPREP00000026798	Transmembrane protein 150C. (201 aa)
	abl2	Tyrosine-protein kinase. (1187 aa)
	ucn	Urotensin 1. (147 aa)
	TNNI2	Troponin I type 2b (skeletal, fast), tandem duplicate 1. (174 aa)
	gch1	GTP cyclohydrolase 1. (255 aa)
	stac3	SH3 and cysteine rich domain 3. (333 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (455 aa)
	grin2a	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a. (1552 aa)
	HOMER1	Homer scaffold protein 1. (377 aa)
	agtpbp1	ATP/GTP binding protein 1. (1264 aa)
	ENSPREP00000028482	Uncharacterized protein. (587 aa)
	tnni1	Troponin I type 1a (skeletal, slow). (205 aa)
	LOC103472149	Uncharacterized protein. (663 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
	LOC103467376	Homeobox C10a. (340 aa)
	vps54	VPS54 subunit of GARP complex. (1027 aa)
	stac	SH3 and cysteine rich domain. (446 aa)
	ush1c	Usher syndrome 1C. (553 aa)
	hexb	Beta-hexosaminidase. (546 aa)
	pou4f1	POU domain protein. (334 aa)
	LOC103475259	Clarin 1. (200 aa)
	LOC103481250	Uncharacterized protein. (416 aa)
	LOC103470521	Glycine receptor, beta a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (500 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (288 aa)
	Igdcc3	Immunoglobulin superfamily, DCC subclass, member 3. (355 aa)
	ENSPREP00000033672	Immunoglobulin superfamily, DCC subclass, member 3. (451 aa)
	ENSPREP00000034105	Proline-rich transmembrane protein 2. (159 aa)
	LOC103471340	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (440 aa)
	pou4f2	POU domain protein. (386 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002982	LOC103464710	ENSPREP00000002982	ENSPREP00000018100	Troponin I2, fast skeletal type.	Troponin I type 1b (skeletal, slow).	0.642
ENSPREP00000002982	LOC103465819	ENSPREP00000002982	ENSPREP00000012191	Troponin I2, fast skeletal type.	Troponin I4a.	0.593
ENSPREP00000002982	LOC103465820	ENSPREP00000002982	ENSPREP00000012264	Troponin I2, fast skeletal type.	Troponin I4b, tandem duplicate 2.	0.589
ENSPREP00000002982	LOC103465821	ENSPREP00000002982	ENSPREP00000012478	Troponin I2, fast skeletal type.	Uncharacterized protein.	0.588
ENSPREP00000002982	LOC103465822	ENSPREP00000002982	ENSPREP00000012522	Troponin I2, fast skeletal type.	Troponin I4b, tandem duplicate 2.	0.598
ENSPREP00000002982	LOC103466898	ENSPREP00000002982	ENSPREP00000005662	Troponin I2, fast skeletal type.	Si:rp71-17i16.4.	0.902
ENSPREP00000002982	LOC103466900	ENSPREP00000002982	ENSPREP00000005708	Troponin I2, fast skeletal type.	Troponin C type 2 (fast).	0.914
ENSPREP00000002982	LOC103468062	ENSPREP00000002982	ENSPREP00000003392	Troponin I2, fast skeletal type.	Troponin C type 1b (slow).	0.792
ENSPREP00000002982	TNNC1	ENSPREP00000002982	ENSPREP00000011929	Troponin I2, fast skeletal type.	Troponin C type 1a (slow).	0.792
ENSPREP00000002982	TNNI2	ENSPREP00000002982	ENSPREP00000027370	Troponin I2, fast skeletal type.	Troponin I type 2b (skeletal, fast), tandem duplicate 1.	0.409
ENSPREP00000002982	tnni1	ENSPREP00000002982	ENSPREP00000029394	Troponin I2, fast skeletal type.	Troponin I type 1a (skeletal, slow).	0.643
ENSPREP00000010244	Mycbp2	ENSPREP00000010244	ENSPREP00000010212	Uncharacterized protein.	RING-type domain-containing protein.	0.930
ENSPREP00000016378	Mtor	ENSPREP00000016378	ENSPREP00000016474	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase TOR.	0.934
ENSPREP00000020277	fxn	ENSPREP00000020277	ENSPREP00000018219	RBR-type E3 ubiquitin transferase.	Frataxin.	0.468
ENSPREP00000033672	Igdcc3	ENSPREP00000033672	ENSPREP00000033669	Immunoglobulin superfamily, DCC subclass, member 3.	Immunoglobulin superfamily, DCC subclass, member 3.	0.911
ENSPREP00000034105	LOC103460857	ENSPREP00000034105	ENSPREP00000021334	Proline-rich transmembrane protein 2.	PNKD metallo-beta-lactamase domain containing.	0.472
ENSPREP00000034105	LOC103478929	ENSPREP00000034105	ENSPREP00000002406	Proline-rich transmembrane protein 2.	Si:ch73-71c20.5.	0.472
GRIN3A	LOC103462623	ENSPREP00000007801	ENSPREP00000000034	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b.	0.573
GRIN3A	LOC103468798	ENSPREP00000007801	ENSPREP00000018974	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b.	0.573
GRIN3A	LOC103469050	ENSPREP00000007801	ENSPREP00000019226	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca.	0.573