(90 nodes) Sensory perception of mechanical stimulus network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	clrn2	Clarin 2. (231 aa)
	phf24	PHD finger protein 24. (402 aa)
	myo3a	Myosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1787 aa)
	ENSPREP00000001561	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (259 aa)
	pgap1	Post-GPI attachment to proteins 1. (931 aa)
	EPYC	Epiphycan. (272 aa)
	ENSPREP00000002838	LHFPL tetraspan subfamily member 4a. (217 aa)
	loxhd1	Lipoxygenase homology domains 1a. (2007 aa)
	LOC103464905	LHFPL tetraspan subfamily member 5a. (224 aa)
	LOC103479610	Espin like b. (680 aa)
	kcnq1	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (631 aa)
	myo3b	Myosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1265 aa)
	LOC103481548	Uncharacterized protein. (895 aa)
	ENSPREP00000007772	Glutaredoxin and cysteine rich domain containing 1 b. (130 aa)
	LOC103457483	Otoferlin a. (1904 aa)
	GRXCR2	Glutaredoxin and cysteine rich domain containing 2. (250 aa)
	adgrv1	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6188 aa)
	pou4f3	POU domain protein. (347 aa)
	tmtc4	Transmembrane O-mannosyltransferase targeting cadherins 4. (741 aa)
	clrn3	Clarin 3. (222 aa)
	LOC103458736	Thrombospondin-type laminin G domain and EAR repeats a. (701 aa)
	ENSPREP00000009325	GRB2 related adaptor protein b. (229 aa)
	ENSPREP00000009358	Uncharacterized protein. (158 aa)
	mkks	McKusick-Kaufman syndrome. (576 aa)
	tmie	Transmembrane inner ear. (229 aa)
	ripor2	RHO family interacting cell polarization regulator 2. (1067 aa)
	scarb2	Scavenger receptor class B, member 2a; Belongs to the CD36 family. (530 aa)
	ddit3	DNA-damage-inducible transcript 3. (309 aa)
	LOC103476047	Sprouty RTK signaling antagonist 2. (349 aa)
	TMC1	Transmembrane channel-like protein. (901 aa)
	LOC103470576	Transmembrane channel-like protein. (876 aa)
	LOC103473662	Scavenger receptor class B, member 2c; Belongs to the CD36 family. (481 aa)
	LOC103466557	Beta-hexosaminidase. (532 aa)
	ENSPREP00000014929	Wolfram syndrome 1a (wolframin). (784 aa)
	LOC103474919	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (762 aa)
	PDZD7	PDZ domain containing 7. (804 aa)
	eya4	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (613 aa)
	tectb	Tectorin beta. (302 aa)
	LOC103457075	Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (955 aa)
	ush2a	Usher syndrome 2A (autosomal recessive, mild). (4818 aa)
	KCNK4	Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (326 aa)
	LOC103470677	MARVEL domain containing 2b. (556 aa)
	slc26a5	Solute carrier family 26 member 5. (711 aa)
	grxcr1	Glutaredoxin and cysteine rich domain containing 1 a. (284 aa)
	LOC103476272	POU domain protein. (350 aa)
	hpn	Hepsin; Belongs to the peptidase S1 family. (427 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
	tmem132e	Transmembrane protein 132E. (1031 aa)
	LOC103476310	Transmembrane protein 120A. (347 aa)
	LOC103470113	Lipoxygenase homology domains 1b. (1913 aa)
	LOC103471448	Potassium channel, subfamily K, member 4a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (492 aa)
	ENSPREP00000022506	Espin like a. (933 aa)
	otof	Otoferlin b. (1641 aa)
	pjvk	Pejvakin. (356 aa)
	tecta	Tectorin alpha. (2196 aa)
	LOC103464861	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (493 aa)
	LOC103469145	GRB2 related adaptor protein a. (214 aa)
	get1	Guided entry of tail-anchored proteins factor 1. (170 aa)
	LOC103473228	MARVEL domain containing 2a. (563 aa)
	LOC103466396	Uncharacterized protein. (226 aa)
	LOC103457071	Fer-1 like family member 6. (1480 aa)
	LOC103469622	Whirlin b. (978 aa)
	espn	Espin. (821 aa)
	trpa1	Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family. (1117 aa)
	eya1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
	LOC103476869	PDZ domain containing 7a. (961 aa)
	lrig1	Leucine-rich repeats and immunoglobulin-like domains 1. (1055 aa)
	tspear	LAM_G_DOMAIN domain-containing protein. (652 aa)
	ucn	Urotensin 1. (147 aa)
	wfs1	Wolfram syndrome 1b (wolframin). (969 aa)
	ENSPREP00000028578	Ion_trans domain-containing protein; Belongs to the potassium channel family. (424 aa)
	LOC103474474	Transmembrane O-methyltransferase. (276 aa)
	crym	Crystallin, mu. (315 aa)
	ENSPREP00000029886	Transmembrane channel-like protein. (789 aa)
	tprn	Taperin. (742 aa)
	cfap57	Cilia and flagella associated protein 57. (1166 aa)
	ush1c	Usher syndrome 1C. (553 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
	hexb	Beta-hexosaminidase. (546 aa)
	whrn	Whirlin a. (828 aa)
	MYO6	Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1214 aa)
	LOC103476954	Dorsal root ganglia homeobox. (254 aa)
	LOC103475259	Clarin 1. (200 aa)
	Lhfpl3	LHFPL tetraspan subfamily member 3. (226 aa)
	pawr	PRKC, apoptosis, WT1, regulator. (280 aa)
	p2rx2	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (414 aa)
	ripor3	RIPOR family member 3. (1001 aa)
	lhfpl5	LHFPL tetraspan subfamily member 5b. (218 aa)
	ENSPREP00000033999	Otospiralin. (95 aa)
	LOC103477049	Uncharacterized protein. (880 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002838	TMC1	ENSPREP00000002838	ENSPREP00000013428	LHFPL tetraspan subfamily member 4a.	Transmembrane channel-like protein.	0.558
ENSPREP00000002838	tmie	ENSPREP00000002838	ENSPREP00000010972	LHFPL tetraspan subfamily member 4a.	Transmembrane inner ear.	0.501
ENSPREP00000007772	GRXCR2	ENSPREP00000007772	ENSPREP00000008228	Glutaredoxin and cysteine rich domain containing 1 b.	Glutaredoxin and cysteine rich domain containing 2.	0.516
ENSPREP00000007772	myo3a	ENSPREP00000007772	ENSPREP00000001085	Glutaredoxin and cysteine rich domain containing 1 b.	Myosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.462
ENSPREP00000007772	myo3b	ENSPREP00000007772	ENSPREP00000005788	Glutaredoxin and cysteine rich domain containing 1 b.	Myosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.462
ENSPREP00000007772	pjvk	ENSPREP00000007772	ENSPREP00000023607	Glutaredoxin and cysteine rich domain containing 1 b.	Pejvakin.	0.409
ENSPREP00000007772	ripor2	ENSPREP00000007772	ENSPREP00000011590	Glutaredoxin and cysteine rich domain containing 1 b.	RHO family interacting cell polarization regulator 2.	0.419
ENSPREP00000007772	ripor3	ENSPREP00000007772	ENSPREP00000033523	Glutaredoxin and cysteine rich domain containing 1 b.	RIPOR family member 3.	0.419
ENSPREP00000007772	ush1c	ENSPREP00000007772	ENSPREP00000030327	Glutaredoxin and cysteine rich domain containing 1 b.	Usher syndrome 1C.	0.425
ENSPREP00000009325	ENSPREP00000009358	ENSPREP00000009325	ENSPREP00000009358	GRB2 related adaptor protein b.	Uncharacterized protein.	0.559
ENSPREP00000009325	LOC103476047	ENSPREP00000009325	ENSPREP00000013063	GRB2 related adaptor protein b.	Sprouty RTK signaling antagonist 2.	0.565
ENSPREP00000009358	ENSPREP00000009325	ENSPREP00000009358	ENSPREP00000009325	Uncharacterized protein.	GRB2 related adaptor protein b.	0.559
ENSPREP00000009358	LOC103476047	ENSPREP00000009358	ENSPREP00000013063	Uncharacterized protein.	Sprouty RTK signaling antagonist 2.	0.565
ENSPREP00000014929	TMC1	ENSPREP00000014929	ENSPREP00000013428	Wolfram syndrome 1a (wolframin).	Transmembrane channel-like protein.	0.479
ENSPREP00000014929	adgrv1	ENSPREP00000014929	ENSPREP00000008279	Wolfram syndrome 1a (wolframin).	Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.	0.471
ENSPREP00000014929	ush2a	ENSPREP00000014929	ENSPREP00000017452	Wolfram syndrome 1a (wolframin).	Usher syndrome 2A (autosomal recessive, mild).	0.471
ENSPREP00000022506	GRXCR2	ENSPREP00000022506	ENSPREP00000008228	Espin like a.	Glutaredoxin and cysteine rich domain containing 2.	0.409
ENSPREP00000022506	LOC103469622	ENSPREP00000022506	ENSPREP00000024882	Espin like a.	Whirlin b.	0.580
ENSPREP00000022506	myo3a	ENSPREP00000022506	ENSPREP00000001085	Espin like a.	Myosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.694
ENSPREP00000022506	myo3b	ENSPREP00000022506	ENSPREP00000005788	Espin like a.	Myosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.694