(35 nodes) Detection of mechanical stimulus network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KCNK4	Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (326 aa)
	PDZD7	PDZ domain containing 7. (804 aa)
	LOC103474919	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (762 aa)
	LOC103470576	Transmembrane channel-like protein. (876 aa)
	TMC1	Transmembrane channel-like protein. (901 aa)
	piezo1	Piezo-type mechanosensitive ion channel component. (2314 aa)
	mkks	McKusick-Kaufman syndrome. (576 aa)
	kcnq1	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (631 aa)
	lrriq1	Uncharacterized protein. (1372 aa)
	LOC103477109	Polycystic kidney disease 2-like 1. (756 aa)
	pkd2	Polycystic kidney disease 2. (893 aa)
	ENSPREP00000001895	Piezo_RRas_bdg domain-containing protein. (569 aa)
	ENSPREP00000001831	Uncharacterized protein. (301 aa)
	phf24	PHD finger protein 24. (402 aa)
	LOC103465321	Junction plakoglobin a. (721 aa)
	pkd1	Polycystic kidney disease 1a. (4592 aa)
	pawr	PRKC, apoptosis, WT1, regulator. (280 aa)
	whrn	Whirlin a. (828 aa)
	ENSPREP00000029886	Transmembrane channel-like protein. (789 aa)
	LOC103474474	Transmembrane O-methyltransferase. (276 aa)
	csrp3	Cysteine and glycine-rich protein 3 (cardiac LIM protein). (193 aa)
	ENSPREP00000028578	Ion_trans domain-containing protein; Belongs to the potassium channel family. (424 aa)
	LOC103476869	PDZ domain containing 7a. (961 aa)
	trpa1	Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family. (1117 aa)
	PIEZO2	Piezo-type mechanosensitive ion channel component. (2643 aa)
	LOC103469622	Whirlin b. (978 aa)
	LOC103478146	Si:dkey-71b5.7. (1137 aa)
	LOC103460357	Uncharacterized protein. (1583 aa)
	pjvk	Pejvakin. (356 aa)
	LOC103471448	Potassium channel, subfamily K, member 4a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (492 aa)
	LOC103476310	Transmembrane protein 120A. (347 aa)
	pkd1l1	Uncharacterized protein. (2056 aa)
	tmem132e	Transmembrane protein 132E. (1031 aa)
	hpn	Hepsin; Belongs to the peptidase S1 family. (427 aa)
	tcap	Titin-cap (telethonin). (187 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000001831	ENSPREP00000001895	ENSPREP00000001831	ENSPREP00000001895	Uncharacterized protein.	Piezo_RRas_bdg domain-containing protein.	0.936
ENSPREP00000001895	ENSPREP00000001831	ENSPREP00000001895	ENSPREP00000001831	Piezo_RRas_bdg domain-containing protein.	Uncharacterized protein.	0.936
LOC103460357	LOC103477109	ENSPREP00000023960	ENSPREP00000003780	Uncharacterized protein.	Polycystic kidney disease 2-like 1.	0.754
LOC103460357	pkd1	ENSPREP00000023960	ENSPREP00000000547	Uncharacterized protein.	Polycystic kidney disease 1a.	0.401
LOC103460357	pkd2	ENSPREP00000023960	ENSPREP00000002383	Uncharacterized protein.	Polycystic kidney disease 2.	0.754
LOC103469622	LOC103478146	ENSPREP00000024882	ENSPREP00000024019	Whirlin b.	Si:dkey-71b5.7.	0.404
LOC103469622	TMC1	ENSPREP00000024882	ENSPREP00000013428	Whirlin b.	Transmembrane channel-like protein.	0.416
LOC103477109	LOC103460357	ENSPREP00000003780	ENSPREP00000023960	Polycystic kidney disease 2-like 1.	Uncharacterized protein.	0.754
LOC103477109	pkd1	ENSPREP00000003780	ENSPREP00000000547	Polycystic kidney disease 2-like 1.	Polycystic kidney disease 1a.	0.930
LOC103478146	LOC103469622	ENSPREP00000024019	ENSPREP00000024882	Si:dkey-71b5.7.	Whirlin b.	0.404
LOC103478146	pjvk	ENSPREP00000024019	ENSPREP00000023607	Si:dkey-71b5.7.	Pejvakin.	0.434
LOC103478146	whrn	ENSPREP00000024019	ENSPREP00000031133	Si:dkey-71b5.7.	Whirlin a.	0.404
TMC1	LOC103469622	ENSPREP00000013428	ENSPREP00000024882	Transmembrane channel-like protein.	Whirlin b.	0.416
TMC1	trpa1	ENSPREP00000013428	ENSPREP00000026537	Transmembrane channel-like protein.	Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family.	0.454
TMC1	whrn	ENSPREP00000013428	ENSPREP00000031133	Transmembrane channel-like protein.	Whirlin a.	0.416
csrp3	tcap	ENSPREP00000028608	ENSPREP00000016351	Cysteine and glycine-rich protein 3 (cardiac LIM protein).	Titin-cap (telethonin).	0.671
pjvk	LOC103478146	ENSPREP00000023607	ENSPREP00000024019	Pejvakin.	Si:dkey-71b5.7.	0.434
pkd1	LOC103460357	ENSPREP00000000547	ENSPREP00000023960	Polycystic kidney disease 1a.	Uncharacterized protein.	0.401
pkd1	LOC103477109	ENSPREP00000000547	ENSPREP00000003780	Polycystic kidney disease 1a.	Polycystic kidney disease 2-like 1.	0.930
pkd1	pkd2	ENSPREP00000000547	ENSPREP00000002383	Polycystic kidney disease 1a.	Polycystic kidney disease 2.	0.931