(17 nodes) Protein heterooligomerization network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cpsf6	Cleavage and polyadenylation specific factor 6. (586 aa)
	pkd1	Polycystic kidney disease 1a. (4592 aa)
	calhm1	Calcium homeostasis modulator 1. (351 aa)
	nudt21	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (229 aa)
	pkd2	Polycystic kidney disease 2. (893 aa)
	LOC103472946	Hydroxysteroid (17-beta) dehydrogenase 8. (204 aa)
	LOC103476014	Retinal outer segment membrane protein 1a. (347 aa)
	prph2	Peripherin 2a (retinal degeneration, slow). (344 aa)
	farsb	Phenylalanyl-tRNA synthetase subunit beta; Belongs to the EF-1-beta/EF-1-delta family. (875 aa)
	LOC103458995	Peripherin 2-like a. (366 aa)
	LOC103457115	Uncharacterized protein. (356 aa)
	farsa	Phenylalanyl-tRNA synthetase subunit alpha. (471 aa)
	LOC103477409	Peripherin 2b (retinal degeneration, slow). (344 aa)
	rom1	Retinal outer segment membrane protein 1b. (361 aa)
	cbr4	Carbonyl reductase 4. (238 aa)
	calhm3	Calcium homeostasis modulator 3. (330 aa)
	CPSF7	Cleavage and polyadenylation specific factor 7. (451 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPSF7	cpsf6	ENSPREP00000033868	ENSPREP00000006376	Cleavage and polyadenylation specific factor 7.	Cleavage and polyadenylation specific factor 6.	0.904
CPSF7	nudt21	ENSPREP00000033868	ENSPREP00000001735	Cleavage and polyadenylation specific factor 7.	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.963
LOC103457115	rom1	ENSPREP00000019980	ENSPREP00000023025	Uncharacterized protein.	Retinal outer segment membrane protein 1b.	0.719
LOC103458995	rom1	ENSPREP00000016675	ENSPREP00000023025	Peripherin 2-like a.	Retinal outer segment membrane protein 1b.	0.719
LOC103472946	cbr4	ENSPREP00000006770	ENSPREP00000027583	Hydroxysteroid (17-beta) dehydrogenase 8.	Carbonyl reductase 4.	0.996
LOC103476014	rom1	ENSPREP00000008136	ENSPREP00000023025	Retinal outer segment membrane protein 1a.	Retinal outer segment membrane protein 1b.	0.877
LOC103477409	rom1	ENSPREP00000020167	ENSPREP00000023025	Peripherin 2b (retinal degeneration, slow).	Retinal outer segment membrane protein 1b.	0.717
cbr4	LOC103472946	ENSPREP00000027583	ENSPREP00000006770	Carbonyl reductase 4.	Hydroxysteroid (17-beta) dehydrogenase 8.	0.996
cpsf6	CPSF7	ENSPREP00000006376	ENSPREP00000033868	Cleavage and polyadenylation specific factor 6.	Cleavage and polyadenylation specific factor 7.	0.904
cpsf6	nudt21	ENSPREP00000006376	ENSPREP00000001735	Cleavage and polyadenylation specific factor 6.	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.975
farsa	farsb	ENSPREP00000020144	ENSPREP00000015674	Phenylalanyl-tRNA synthetase subunit alpha.	Phenylalanyl-tRNA synthetase subunit beta; Belongs to the EF-1-beta/EF-1-delta family.	0.999
farsb	farsa	ENSPREP00000015674	ENSPREP00000020144	Phenylalanyl-tRNA synthetase subunit beta; Belongs to the EF-1-beta/EF-1-delta family.	Phenylalanyl-tRNA synthetase subunit alpha.	0.999
nudt21	CPSF7	ENSPREP00000001735	ENSPREP00000033868	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Cleavage and polyadenylation specific factor 7.	0.963
nudt21	cpsf6	ENSPREP00000001735	ENSPREP00000006376	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Cleavage and polyadenylation specific factor 6.	0.975
pkd1	pkd2	ENSPREP00000000547	ENSPREP00000002383	Polycystic kidney disease 1a.	Polycystic kidney disease 2.	0.931
pkd2	pkd1	ENSPREP00000002383	ENSPREP00000000547	Polycystic kidney disease 2.	Polycystic kidney disease 1a.	0.931
prph2	rom1	ENSPREP00000013514	ENSPREP00000023025	Peripherin 2a (retinal degeneration, slow).	Retinal outer segment membrane protein 1b.	0.717
rom1	LOC103457115	ENSPREP00000023025	ENSPREP00000019980	Retinal outer segment membrane protein 1b.	Uncharacterized protein.	0.719
rom1	LOC103458995	ENSPREP00000023025	ENSPREP00000016675	Retinal outer segment membrane protein 1b.	Peripherin 2-like a.	0.719
rom1	LOC103476014	ENSPREP00000023025	ENSPREP00000008136	Retinal outer segment membrane protein 1b.	Retinal outer segment membrane protein 1a.	0.877