(112 nodes) Defense response to virus network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bnip3	BCL2 interacting protein 3. (178 aa)
	LOC103473458	Zgc:73226. (215 aa)
	pqbp1	Polyglutamine binding protein 1. (153 aa)
	ENSPREP00000003758	Pyrin domain-containing protein. (110 aa)
	serinc5	Serine incorporator 5. (459 aa)
	ENSPREP00000004007	Uncharacterized protein. (289 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1057 aa)
	ENSPREP00000004424	Uncharacterized protein. (453 aa)
	ENSPREP00000004459	Uncharacterized protein. (181 aa)
	trim8	Tripartite motif containing 8b. (595 aa)
	LOC103475332	Interferon regulatory factor. (291 aa)
	LOC103481391	Uncharacterized protein. (476 aa)
	ENSPREP00000032598	Uncharacterized protein. (152 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (818 aa)
	LOC103481249	Interferon regulatory factor 3. (465 aa)
	ABCF3	ATP binding cassette subfamily F member 3. (335 aa)
	Abcf3	ATP-binding cassette, sub-family F (GCN20), member 3. (269 aa)
	LOC103473973	BCL2 interacting protein 3 like b. (205 aa)
	rsad2	Radical S-adenosyl methionine domain containing 2. (350 aa)
	tnfrsf18	CD40 molecule, TNF receptor superfamily member 5. (314 aa)
	ENSPREP00000031073	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (323 aa)
	ENSPREP00000030719	Uncharacterized protein. (708 aa)
	LOC103476933	RING-type domain-containing protein. (561 aa)
	ENSPREP00000030269	Uncharacterized protein. (785 aa)
	ENSPREP00000030263	Uncharacterized protein. (812 aa)
	ENSPREP00000030231	Uncharacterized protein. (800 aa)
	zmynd11	Zinc finger, MYND-type containing 11. (663 aa)
	LOC103465029	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (618 aa)
	ENSPREP00000028517	ANK_REP_REGION domain-containing protein. (336 aa)
	irf7	Interferon regulatory factor 7. (472 aa)
	CLPB	ClpB homolog, mitochondrial AAA ATPase chaperonin. (682 aa)
	LOC103465031	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (646 aa)
	LOC103464064	ATP/GTP binding protein-like 4. (543 aa)
	LOC103465032	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (636 aa)
	ENSPREP00000027416	HD domain-containing protein. (178 aa)
	LOC103467467	SAM domain and HD domain 1. (627 aa)
	LOC103467464	HD domain-containing protein. (433 aa)
	LOC103470751	Protein kinase domain-containing protein. (488 aa)
	exosc5	Exosome component 5. (236 aa)
	adar	Adenosine deaminase RNA specific. (1358 aa)
	agbl5	ATP/GTP binding protein-like 5. (966 aa)
	LOC103470783	CARD domain-containing protein. (434 aa)
	ENSPREP00000025343	Uncharacterized protein. (208 aa)
	LOC103466382	LSM14A mRNA processing body assembly factor a. (480 aa)
	trim32	Tripartite motif containing 32. (628 aa)
	LOC103479830	Opioid receptor, kappa 1; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	ENSPREP00000022805	V-SNARE coiled-coil homology domain-containing protein. (116 aa)
	ENSPREP00000022754	Vesicle-associated membrane protein 8 (endobrevin). (118 aa)
	ENSPREP00000022564	RING-type domain-containing protein. (200 aa)
	akap1	A kinase (PRKA) anchor protein 1b. (821 aa)
	ENSPREP00000021383	GUCT domain-containing protein. (129 aa)
	LOC103466013	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (443 aa)
	nmbr	Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (391 aa)
	ilf3	Interleukin enhancer binding factor 3b. (825 aa)
	ENSPREP00000018366	Uncharacterized protein. (128 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1230 aa)
	LOC103462757	IRF tryptophan pentad repeat domain-containing protein. (268 aa)
	ENSPREP00000018105	Uncharacterized protein. (204 aa)
	LOC103463313	TLDc domain-containing protein. (464 aa)
	LOC103463495	G domain-containing protein. (278 aa)
	ENSPREP00000017493	TLDc domain-containing protein. (383 aa)
	LOC103463314	G domain-containing protein. (480 aa)
	ddx1	DEAD (Asp-Glu-Ala-Asp) box helicase 1. (740 aa)
	ENSPREP00000017414	Uncharacterized protein. (402 aa)
	rnf185	Ring finger protein 185. (193 aa)
	LOC108167267	Uncharacterized protein. (184 aa)
	ENSPREP00000016463	Uncharacterized protein. (111 aa)
	LOC103457742	Uncharacterized protein. (343 aa)
	spon2	Spondin 2b, extracellular matrix protein. (338 aa)
	LOC103481345	ULP_PROTEASE domain-containing protein. (802 aa)
	armc5	Armadillo repeat containing 5. (841 aa)
	dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58. (681 aa)
	riok3	Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (504 aa)
	ttc4	Tetratricopeptide repeat domain 4. (396 aa)
	exosc4	Exosome component 4. (245 aa)
	znfx1	Zinc finger, NFX1-type containing 1. (1816 aa)
	LOC103468247	TLDc domain-containing protein. (444 aa)
	aicda	Activation-induced cytidine deaminase. (211 aa)
	LOC103468661	Mitogen-activated protein kinase kinase kinase 14a. (869 aa)
	LOC103481612	ADP-ribosylation factor 2b. (786 aa)
	LOC103470563	BCL2 interacting protein 3 like a. (238 aa)
	phb	Prohibitin. (271 aa)
	ENSPREP00000012104	Phospholipase A(2). (160 aa)
	LOC103477355	Protein kinase domain-containing protein. (582 aa)
	ENSPREP00000011628	Uncharacterized protein. (564 aa)
	LOC103477270	Uncharacterized protein. (689 aa)
	polr3k	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
	ifih1	Interferon induced with helicase C domain 1. (969 aa)
	lsm14a	LSM14A mRNA processing body assembly factor b. (463 aa)
	polr3d	Polymerase (RNA) III (DNA directed) polypeptide D. (391 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (323 aa)
	ENSPREP00000010947	Uncharacterized protein. (306 aa)
	senp7	SUMO specific peptidase 7. (1027 aa)
	ENSPREP00000010333	RNA_pol_Rbc25 domain-containing protein. (230 aa)
	oprk1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	acod1	Aconitate decarboxylase 1. (531 aa)
	ENSPREP00000009629	TLDc domain-containing protein. (196 aa)
	polr3f	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (341 aa)
	ENSPREP00000006991	Uncharacterized protein. (331 aa)
	DHX15	DEAH-box helicase 15. (763 aa)
	sting1	Transmembrane protein 173. (484 aa)
	bcl2	BCL2 apoptosis regulator b. (230 aa)
	LOC103471240	Spondin 2a, extracellular matrix protein. (334 aa)
	ENSPREP00000000878	Uncharacterized protein. (421 aa)
	LOC103471006	Interferon regulatory factor 2. (423 aa)
	zdhhc1	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (537 aa)
	ENSPREP00000002275	DED domain-containing protein. (147 aa)
	ENSPREP00000002598	Uncharacterized protein. (117 aa)
	ENSPREP00000002617	Uncharacterized protein. (98 aa)
	LOC103459167	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1052 aa)
	ndufaf4	NADH:ubiquinone oxidoreductase complex assembly factor 4. (175 aa)
	ENSPREP00000003308	Uncharacterized protein. (202 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCF3	Abcf3	ENSPREP00000032315	ENSPREP00000032290	ATP binding cassette subfamily F member 3.	ATP-binding cassette, sub-family F (GCN20), member 3.	0.900
ABCF3	CLPB	ENSPREP00000032315	ENSPREP00000028464	ATP binding cassette subfamily F member 3.	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.402
Abcf3	ABCF3	ENSPREP00000032290	ENSPREP00000032315	ATP-binding cassette, sub-family F (GCN20), member 3.	ATP binding cassette subfamily F member 3.	0.900
Abcf3	CLPB	ENSPREP00000032290	ENSPREP00000028464	ATP-binding cassette, sub-family F (GCN20), member 3.	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.402
CLPB	ABCF3	ENSPREP00000028464	ENSPREP00000032315	ClpB homolog, mitochondrial AAA ATPase chaperonin.	ATP binding cassette subfamily F member 3.	0.402
CLPB	Abcf3	ENSPREP00000028464	ENSPREP00000032290	ClpB homolog, mitochondrial AAA ATPase chaperonin.	ATP-binding cassette, sub-family F (GCN20), member 3.	0.402
CLPB	ENSPREP00000028517	ENSPREP00000028464	ENSPREP00000028517	ClpB homolog, mitochondrial AAA ATPase chaperonin.	ANK_REP_REGION domain-containing protein.	0.591
CLPB	phb	ENSPREP00000028464	ENSPREP00000012361	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Prohibitin.	0.432
DHX15	ENSPREP00000021383	ENSPREP00000006773	ENSPREP00000021383	DEAH-box helicase 15.	GUCT domain-containing protein.	0.755
DHX15	ddx1	ENSPREP00000006773	ENSPREP00000017418	DEAH-box helicase 15.	DEAD (Asp-Glu-Ala-Asp) box helicase 1.	0.699
DHX15	exosc4	ENSPREP00000006773	ENSPREP00000014202	DEAH-box helicase 15.	Exosome component 4.	0.549
DHX15	exosc5	ENSPREP00000006773	ENSPREP00000026216	DEAH-box helicase 15.	Exosome component 5.	0.417
ENSPREP00000000878	ifih1	ENSPREP00000000878	ENSPREP00000011433	Uncharacterized protein.	Interferon induced with helicase C domain 1.	0.551
ENSPREP00000000878	rsad2	ENSPREP00000000878	ENSPREP00000031618	Uncharacterized protein.	Radical S-adenosyl methionine domain containing 2.	0.552
ENSPREP00000002275	LOC103466013	ENSPREP00000002275	ENSPREP00000021307	DED domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.991
ENSPREP00000002275	LOC103470751	ENSPREP00000002275	ENSPREP00000027001	DED domain-containing protein.	Protein kinase domain-containing protein.	0.671
ENSPREP00000002275	bcl2	ENSPREP00000002275	ENSPREP00000006116	DED domain-containing protein.	BCL2 apoptosis regulator b.	0.484
ENSPREP00000002598	ptprc	ENSPREP00000002598	ENSPREP00000018309	Uncharacterized protein.	Protein tyrosine phosphatase receptor type C.	0.532
ENSPREP00000002617	ptprc	ENSPREP00000002617	ENSPREP00000018309	Uncharacterized protein.	Protein tyrosine phosphatase receptor type C.	0.532
ENSPREP00000004007	ifih1	ENSPREP00000004007	ENSPREP00000011433	Uncharacterized protein.	Interferon induced with helicase C domain 1.	0.551