(22 nodes) Definitive hemopoiesis network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cbfb	Core-binding factor subunit beta. (184 aa)
	Tal1	BHLH domain-containing protein. (124 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	ENSPREP00000003831	Uncharacterized protein. (102 aa)
	SP3	Sp3a transcription factor. (699 aa)
	LOC103458727	Sp3b transcription factor. (680 aa)
	LOC103458735	Small ubiquitin-related modifier. (94 aa)
	ENSPREP00000013251	Microfibril associated protein 5. (141 aa)
	LOC103461674	Ubiquitin-like domain-containing protein. (161 aa)
	gar1	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (234 aa)
	cdk5rap3	CDK5 regulatory subunit associated protein 3. (506 aa)
	LOC103468369	BHLH domain-containing protein. (458 aa)
	kri1	KRI1 homolog. (752 aa)
	sumo1	Small ubiquitin like modifier 1. (205 aa)
	rps24	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (139 aa)
	LOC103467943	Small ubiquitin-related modifier. (96 aa)
	Mib1	Mindbomb E3 ubiquitin protein ligase 1. (994 aa)
	adar	Adenosine deaminase RNA specific. (1358 aa)
	LOC103479412	T-cell acute lymphocytic leukemia 1. (394 aa)
	ube2i	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	sae1	SUMO1 activating enzyme subunit 1. (344 aa)
	LOC103468487	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103458727	sumo1	ENSPREP00000008503	ENSPREP00000022120	Sp3b transcription factor.	Small ubiquitin like modifier 1.	0.452
LOC103458735	LOC103468487	ENSPREP00000009093	ENSPREP00000027513	Small ubiquitin-related modifier.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.983
LOC103458735	sae1	ENSPREP00000009093	ENSPREP00000029023	Small ubiquitin-related modifier.	SUMO1 activating enzyme subunit 1.	0.916
LOC103458735	sumo1	ENSPREP00000009093	ENSPREP00000022120	Small ubiquitin-related modifier.	Small ubiquitin like modifier 1.	0.661
LOC103458735	ube2i	ENSPREP00000009093	ENSPREP00000026310	Small ubiquitin-related modifier.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.983
LOC103461674	LOC103468487	ENSPREP00000013358	ENSPREP00000027513	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.838
LOC103461674	sae1	ENSPREP00000013358	ENSPREP00000029023	Ubiquitin-like domain-containing protein.	SUMO1 activating enzyme subunit 1.	0.916
LOC103461674	sumo1	ENSPREP00000013358	ENSPREP00000022120	Ubiquitin-like domain-containing protein.	Small ubiquitin like modifier 1.	0.674
LOC103461674	ube2i	ENSPREP00000013358	ENSPREP00000026310	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.838
LOC103467943	LOC103468487	ENSPREP00000024574	ENSPREP00000027513	Small ubiquitin-related modifier.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.983
LOC103467943	sae1	ENSPREP00000024574	ENSPREP00000029023	Small ubiquitin-related modifier.	SUMO1 activating enzyme subunit 1.	0.928
LOC103467943	sumo1	ENSPREP00000024574	ENSPREP00000022120	Small ubiquitin-related modifier.	Small ubiquitin like modifier 1.	0.661
LOC103467943	ube2i	ENSPREP00000024574	ENSPREP00000026310	Small ubiquitin-related modifier.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.983
LOC103468369	cbfb	ENSPREP00000020332	ENSPREP00000027528	BHLH domain-containing protein.	Core-binding factor subunit beta.	0.705
LOC103468487	LOC103458735	ENSPREP00000027513	ENSPREP00000009093	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.983
LOC103468487	LOC103461674	ENSPREP00000027513	ENSPREP00000013358	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-like domain-containing protein.	0.838
LOC103468487	LOC103467943	ENSPREP00000027513	ENSPREP00000024574	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.983
LOC103468487	sae1	ENSPREP00000027513	ENSPREP00000029023	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	SUMO1 activating enzyme subunit 1.	0.958
LOC103468487	sumo1	ENSPREP00000027513	ENSPREP00000022120	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin like modifier 1.	0.997
LOC103468487	sumo2	ENSPREP00000027513	ENSPREP00000002821	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.983