(23 nodes) Ectodermal placode formation network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103456513	Uncharacterized protein. (883 aa)
	mdn1	Midasin AAA ATPase 1. (3952 aa)
	ENSPREP00000001981	Uncharacterized protein. (359 aa)
	LOC103481447	Paired box 2b. (392 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (236 aa)
	LOC103471035	Mothers against decapentaplegic homolog. (475 aa)
	dlx3	Distal-less homeobox 3b. (281 aa)
	eda	Ectodysplasin A; Belongs to the tumor necrosis factor family. (369 aa)
	Nrg3	EGF-like domain-containing protein. (95 aa)
	pax5	Paired box 5. (396 aa)
	axin1	Axin 1. (850 aa)
	fst	Follistatin a. (351 aa)
	chrd	Chordin; Belongs to the chordin family. (949 aa)
	LOC103482434	Forkhead box H1. (633 aa)
	pax8	Paired box 8. (495 aa)
	ENSPREP00000025214	Paired domain-containing protein. (156 aa)
	ENSPREP00000025759	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
	LOC103476847	Paired box 2a. (322 aa)
	rax	Retinal homeobox gene 3. (310 aa)
	gata3	GATA binding protein 3. (483 aa)
	LOC103476521	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	ENSPREP00000033510	Uncharacterized protein. (266 aa)
	LOC103481296	Uncharacterized protein. (562 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000001981	mdn1	ENSPREP00000001981	ENSPREP00000001868	Uncharacterized protein.	Midasin AAA ATPase 1.	0.947
ENSPREP00000025759	LOC103456513	ENSPREP00000025759	ENSPREP00000000160	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.530
ENSPREP00000025759	axin1	ENSPREP00000025759	ENSPREP00000012177	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Axin 1.	0.530
ENSPREP00000033510	LOC103481296	ENSPREP00000033510	ENSPREP00000033518	Uncharacterized protein.	Uncharacterized protein.	0.902
LOC103456513	ENSPREP00000025759	ENSPREP00000000160	ENSPREP00000025759	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.530
LOC103456513	axin1	ENSPREP00000000160	ENSPREP00000012177	Uncharacterized protein.	Axin 1.	0.902
LOC103471035	LOC103482434	ENSPREP00000005305	ENSPREP00000021830	Mothers against decapentaplegic homolog.	Forkhead box H1.	0.555
LOC103471035	chrd	ENSPREP00000005305	ENSPREP00000014581	Mothers against decapentaplegic homolog.	Chordin; Belongs to the chordin family.	0.482
LOC103476521	chrd	ENSPREP00000029747	ENSPREP00000014581	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Chordin; Belongs to the chordin family.	0.486
LOC103476521	dlx3	ENSPREP00000029747	ENSPREP00000006756	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Distal-less homeobox 3b.	0.404
LOC103476521	fgf3	ENSPREP00000029747	ENSPREP00000002583	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.795
LOC103481296	ENSPREP00000033510	ENSPREP00000033518	ENSPREP00000033510	Uncharacterized protein.	Uncharacterized protein.	0.902
LOC103482434	LOC103471035	ENSPREP00000021830	ENSPREP00000005305	Forkhead box H1.	Mothers against decapentaplegic homolog.	0.555
axin1	ENSPREP00000025759	ENSPREP00000012177	ENSPREP00000025759	Axin 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.530
axin1	LOC103456513	ENSPREP00000012177	ENSPREP00000000160	Axin 1.	Uncharacterized protein.	0.902
chrd	LOC103471035	ENSPREP00000014581	ENSPREP00000005305	Chordin; Belongs to the chordin family.	Mothers against decapentaplegic homolog.	0.482
chrd	LOC103476521	ENSPREP00000014581	ENSPREP00000029747	Chordin; Belongs to the chordin family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.486
chrd	fst	ENSPREP00000014581	ENSPREP00000014118	Chordin; Belongs to the chordin family.	Follistatin a.	0.643
dlx3	LOC103476521	ENSPREP00000006756	ENSPREP00000029747	Distal-less homeobox 3b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.404
dlx3	gata3	ENSPREP00000006756	ENSPREP00000026693	Distal-less homeobox 3b.	GATA binding protein 3.	0.617