(26 nodes) Positive regulation of dendritic spine development network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fmr1	Fragile X mental retardation 1. (273 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1057 aa)
	LOC103468820	BAI1-associated protein 2a. (549 aa)
	eef2k	Eukaryotic elongation factor 2 kinase. (767 aa)
	LOC103477848	Apolipoprotein Eb. (265 aa)
	LOC103470450	Si:dkey-40c11.2. (812 aa)
	dbnl	Drebrin-like b. (479 aa)
	LOC103473017	Apolipoprotein Ea. (251 aa)
	clg14h21orf91	Zgc:110006. (287 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (834 aa)
	Shank1	SAM domain-containing protein. (1628 aa)
	ENSPREP00000017955	C1q domain-containing protein. (310 aa)
	dbn1	Drebrin 1. (528 aa)
	LOC103461055	Fragile X mental retardation 1. (400 aa)
	mapkapk5	MAPK activated protein kinase 5. (471 aa)
	LOC103466031	SH3 and multiple ankyrin repeat domains 3a. (1984 aa)
	BAIAP2	BAI1 associated protein 2. (569 aa)
	LOC103476825	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2011 aa)
	LOC103463007	SH3 and multiple ankyrin repeat domains 2a. (1709 aa)
	cux2	Homeobox protein cut-like. (1544 aa)
	caprin1	Cell cycle associated protein 1b. (686 aa)
	RELN	Reelin. (3446 aa)
	LOC103481054	Uncharacterized protein. (2065 aa)
	mapk6	Mitogen-activated protein kinase 6. (754 aa)
	llph	LLP homolog, long-term synaptic facilitation factor. (115 aa)
	LOC103462434	Cell cycle associated protein 1a. (637 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAIAP2	LOC103468820	ENSPREP00000022196	ENSPREP00000004709	BAI1 associated protein 2.	BAI1-associated protein 2a.	0.901
ENSPREP00000017955	LOC103462434	ENSPREP00000017955	ENSPREP00000033928	C1q domain-containing protein.	Cell cycle associated protein 1a.	0.805
ENSPREP00000017955	caprin1	ENSPREP00000017955	ENSPREP00000023944	C1q domain-containing protein.	Cell cycle associated protein 1b.	0.853
LOC103461055	LOC103462434	ENSPREP00000020915	ENSPREP00000033928	Fragile X mental retardation 1.	Cell cycle associated protein 1a.	0.505
LOC103461055	caprin1	ENSPREP00000020915	ENSPREP00000023944	Fragile X mental retardation 1.	Cell cycle associated protein 1b.	0.505
LOC103461055	fmr1	ENSPREP00000020915	ENSPREP00000004643	Fragile X mental retardation 1.	Fragile X mental retardation 1.	0.932
LOC103462434	ENSPREP00000017955	ENSPREP00000033928	ENSPREP00000017955	Cell cycle associated protein 1a.	C1q domain-containing protein.	0.805
LOC103462434	LOC103461055	ENSPREP00000033928	ENSPREP00000020915	Cell cycle associated protein 1a.	Fragile X mental retardation 1.	0.505
LOC103462434	fmr1	ENSPREP00000033928	ENSPREP00000004643	Cell cycle associated protein 1a.	Fragile X mental retardation 1.	0.505
LOC103463007	LOC103476825	ENSPREP00000023501	ENSPREP00000023100	SH3 and multiple ankyrin repeat domains 2a.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.521
LOC103466031	LOC103476825	ENSPREP00000021990	ENSPREP00000023100	SH3 and multiple ankyrin repeat domains 3a.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.521
LOC103468820	BAIAP2	ENSPREP00000004709	ENSPREP00000022196	BAI1-associated protein 2a.	BAI1 associated protein 2.	0.901
LOC103476825	LOC103463007	ENSPREP00000023100	ENSPREP00000023501	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 2a.	0.521
LOC103476825	LOC103466031	ENSPREP00000023100	ENSPREP00000021990	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 3a.	0.521
LOC103476825	LOC103481054	ENSPREP00000023100	ENSPREP00000025983	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	Uncharacterized protein.	0.521
LOC103476825	Shank1	ENSPREP00000023100	ENSPREP00000015974	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	SAM domain-containing protein.	0.521
LOC103476825	shank1	ENSPREP00000023100	ENSPREP00000015953	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 1.	0.521
LOC103481054	LOC103476825	ENSPREP00000025983	ENSPREP00000023100	Uncharacterized protein.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.521
Shank1	LOC103476825	ENSPREP00000015974	ENSPREP00000023100	SAM domain-containing protein.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.521
Shank1	shank1	ENSPREP00000015974	ENSPREP00000015953	SAM domain-containing protein.	SH3 and multiple ankyrin repeat domains 1.	0.896