63 items (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	unc119	Unc-119 lipid binding chaperone. (219 aa)
	LOC103477155	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (560 aa)
	gprc5b	G protein-coupled receptor, class C, group 5, member Bb. (419 aa)
	ABI1	Abl-interactor 1a. (577 aa)
	LOC103467754	Tyrosine-protein phosphatase non-receptor type. (432 aa)
	ENSPREP00000002283	Uncharacterized protein. (66 aa)
	ENSPREP00000002720	Uncharacterized protein. (221 aa)
	Tgfa	Transforming growth factor, alpha. (166 aa)
	ENSPREP00000003699	SH3 domain-containing protein. (137 aa)
	ENSPREP00000003717	Uncharacterized protein. (76 aa)
	Cav1	Uncharacterized protein. (84 aa)
	LOC103473479	EGF-like domain-containing protein. (217 aa)
	sh3bp5l	SH3-binding domain protein 5-like, a. (427 aa)
	fam72a	Family with sequence similarity 72 member B. (149 aa)
	nrg2	Neuregulin 2b. (712 aa)
	errfi1	ERBB receptor feedback inhibitor 1a. (430 aa)
	LOC103471128	Heparin-binding EGF-like growth factor a. (236 aa)
	LOC103469200	G protein-coupled receptor, class C, group 5, member Ba. (397 aa)
	LOC103475648	Unc-119 lipid binding chaperone. (250 aa)
	LOC103472442	Tyrosine-protein phosphatase non-receptor type. (366 aa)
	LOC103469983	EGF-like domain-containing protein. (154 aa)
	LOC103469984	EGF-like domain-containing protein. (176 aa)
	LOC103465217	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	ENSPREP00000015653	SOCS domain-containing protein. (418 aa)
	Socs5	Suppressor of cytokine signaling 5b. (554 aa)
	zgpat	Zinc finger, CCCH-type with G patch domain. (523 aa)
	DGKQ	Diacylglycerol kinase. (895 aa)
	LOC103458433	Non-specific serine/threonine protein kinase. (507 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (452 aa)
	ptpn2	Tyrosine-protein phosphatase non-receptor type. (360 aa)
	LOC103473128	EGF-like domain-containing protein. (621 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1230 aa)
	DOK7	Docking protein 7. (515 aa)
	Adam17	Pep_M12B_propep domain-containing protein. (290 aa)
	ENSPREP00000021987	ADAM metallopeptidase domain 17b. (508 aa)
	zfyve28	Zinc finger, FYVE domain containing 28. (931 aa)
	LOC103477907	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
	ENSPREP00000022415	FGFR1 oncogene partner. (395 aa)
	LOC103476312	Uncharacterized protein. (857 aa)
	ibtk	Inhibitor of Bruton agammaglobulinemia tyrosine kinase. (1347 aa)
	LOC103464180	Uncharacterized protein. (116 aa)
	GPRC5D	G protein-coupled receptor class C group 5 member D. (451 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (848 aa)
	RELN	Reelin. (3446 aa)
	LOC103458871	ADAM metallopeptidase domain 17a. (800 aa)
	LOC103471376	Uncharacterized protein. (383 aa)
	LOC103478167	Ephrin-A1b; Belongs to the ephrin family. (232 aa)
	ncf1	Neutrophil cytosolic factor 1. (438 aa)
	LOC103472091	SH3-domain binding protein 5a (BTK-associated). (414 aa)
	ENSPREP00000027807	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (393 aa)
	sh3bp5	SH3-domain binding protein 5b (BTK-associated). (464 aa)
	LOC103475452	Neuregulin 2a. (731 aa)
	LOC103466144	Zgc:123278. (130 aa)
	tsg101	Tumor susceptibility 101a. (390 aa)
	LOC103472698	Ephrin-A1a; Belongs to the ephrin family. (221 aa)
	nox4	FAD-binding FR-type domain-containing protein. (540 aa)
	il34	Interleukin 34. (223 aa)
	GREM1	Gremlin. (182 aa)
	LOC103468546	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (220 aa)
	ENSPREP00000030675	Cas scaffold protein family member 4. (795 aa)
	pak2	Non-specific serine/threonine protein kinase. (525 aa)
	ercc6	Excision repair cross-complementation group 6. (1402 aa)
	gas6	Uncharacterized protein. (650 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	LOC103458433	ENSPREP00000001513	ENSPREP00000016553	Abl-interactor 1a.	Non-specific serine/threonine protein kinase.	0.401
ABI1	pak2	ENSPREP00000001513	ENSPREP00000030798	Abl-interactor 1a.	Non-specific serine/threonine protein kinase.	0.401
Adam17	ENSPREP00000021987	ENSPREP00000021960	ENSPREP00000021987	Pep_M12B_propep domain-containing protein.	ADAM metallopeptidase domain 17b.	0.932
Adam17	LOC103458871	ENSPREP00000021960	ENSPREP00000025199	Pep_M12B_propep domain-containing protein.	ADAM metallopeptidase domain 17a.	0.902
Adam17	Tgfa	ENSPREP00000021960	ENSPREP00000003483	Pep_M12B_propep domain-containing protein.	Transforming growth factor, alpha.	0.463
ENSPREP00000002720	ptprc	ENSPREP00000002720	ENSPREP00000018309	Uncharacterized protein.	Protein tyrosine phosphatase receptor type C.	0.471
ENSPREP00000003699	LOC103458433	ENSPREP00000003699	ENSPREP00000016553	SH3 domain-containing protein.	Non-specific serine/threonine protein kinase.	0.401
ENSPREP00000003699	pak2	ENSPREP00000003699	ENSPREP00000030798	SH3 domain-containing protein.	Non-specific serine/threonine protein kinase.	0.401
ENSPREP00000003717	LOC103458433	ENSPREP00000003717	ENSPREP00000016553	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.401
ENSPREP00000003717	pak2	ENSPREP00000003717	ENSPREP00000030798	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.401
ENSPREP00000021987	Adam17	ENSPREP00000021987	ENSPREP00000021960	ADAM metallopeptidase domain 17b.	Pep_M12B_propep domain-containing protein.	0.932
ENSPREP00000021987	Tgfa	ENSPREP00000021987	ENSPREP00000003483	ADAM metallopeptidase domain 17b.	Transforming growth factor, alpha.	0.463
LOC103458433	ABI1	ENSPREP00000016553	ENSPREP00000001513	Non-specific serine/threonine protein kinase.	Abl-interactor 1a.	0.401
LOC103458433	ENSPREP00000003699	ENSPREP00000016553	ENSPREP00000003699	Non-specific serine/threonine protein kinase.	SH3 domain-containing protein.	0.401
LOC103458433	ENSPREP00000003717	ENSPREP00000016553	ENSPREP00000003717	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.401
LOC103458433	pak2	ENSPREP00000016553	ENSPREP00000030798	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.901
LOC103458871	Adam17	ENSPREP00000025199	ENSPREP00000021960	ADAM metallopeptidase domain 17a.	Pep_M12B_propep domain-containing protein.	0.902
LOC103458871	Tgfa	ENSPREP00000025199	ENSPREP00000003483	ADAM metallopeptidase domain 17a.	Transforming growth factor, alpha.	0.463
LOC103467754	il34	ENSPREP00000001691	ENSPREP00000029211	Tyrosine-protein phosphatase non-receptor type.	Interleukin 34.	0.408
LOC103469983	LOC103469984	ENSPREP00000013728	ENSPREP00000013758	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.782