(23 nodes) Regulation of lymphocyte apoptotic process network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prelid1	PRELI domain containing 1a. (210 aa)
	LOC103472698	Ephrin-A1a; Belongs to the ephrin family. (221 aa)
	LOC103458310	Galectin. (351 aa)
	LOC103478167	Ephrin-A1b; Belongs to the ephrin family. (232 aa)
	LOC103457880	Galectin. (300 aa)
	LOC103480947	PRELI domain containing 1b. (192 aa)
	noc2l	NOC2-like nucleolar associated transcriptional repressor. (556 aa)
	LOC103479309	Kinesin-associated protein 3b. (807 aa)
	LOC103466013	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (443 aa)
	LOC103471497	Aurora kinase B; Belongs to the protein kinase superfamily. (350 aa)
	p2rx7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (580 aa)
	LOC103463527	Hematopoietic SH2 domain containing. (378 aa)
	ENSPREP00000013399	Uncharacterized protein. (453 aa)
	BAX	BCL2 associated X, apoptosis regulator. (191 aa)
	LOC103474046	Fibronectin type-III domain-containing protein. (440 aa)
	LOC103461379	Galectin. (233 aa)
	LOC103466417	PRELI/MSF1 domain-containing protein. (213 aa)
	slc46a2	Solute carrier family 46 member 2. (516 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (818 aa)
	il10	Interleukin 10. (229 aa)
	fnip1	Folliculin interacting protein 1. (1222 aa)
	kifap3	Kinesin-associated protein 3a. (745 aa)
	ENSPREP00000002275	DED domain-containing protein. (147 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002275	LOC103466013	ENSPREP00000002275	ENSPREP00000021307	DED domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.991
ENSPREP00000013399	il10	ENSPREP00000013399	ENSPREP00000005577	Uncharacterized protein.	Interleukin 10.	0.536
LOC103466013	ENSPREP00000002275	ENSPREP00000021307	ENSPREP00000002275	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DED domain-containing protein.	0.991
LOC103471497	noc2l	ENSPREP00000020685	ENSPREP00000022642	Aurora kinase B; Belongs to the protein kinase superfamily.	NOC2-like nucleolar associated transcriptional repressor.	0.677
LOC103474046	il10	ENSPREP00000009276	ENSPREP00000005577	Fibronectin type-III domain-containing protein.	Interleukin 10.	0.440
il10	ENSPREP00000013399	ENSPREP00000005577	ENSPREP00000013399	Interleukin 10.	Uncharacterized protein.	0.536
il10	LOC103474046	ENSPREP00000005577	ENSPREP00000009276	Interleukin 10.	Fibronectin type-III domain-containing protein.	0.440
noc2l	LOC103471497	ENSPREP00000022642	ENSPREP00000020685	NOC2-like nucleolar associated transcriptional repressor.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.677