(26 nodes) Actin-mediated cell contraction network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103474422	Sodium channel, voltage-gated, type II, beta. (225 aa)
	LOC103474423	Sodium channel, voltage-gated, type IV, beta a. (233 aa)
	ENSPREP00000027456	Shootin 1. (279 aa)
	ENSPREP00000028578	Ion_trans domain-containing protein; Belongs to the potassium channel family. (424 aa)
	ENSPREP00000024427	IGv domain-containing protein. (354 aa)
	ENSPREP00000024223	Uncharacterized protein. (147 aa)
	ENSPREP00000022056	Si:dkey-280e21.3. (351 aa)
	LOC103458988	Uncharacterized protein. (1012 aa)
	LOC103466375	Uncharacterized protein. (222 aa)
	LOC103480176	Uncharacterized protein. (212 aa)
	LOC103480175	Uncharacterized protein. (213 aa)
	LOC103480173	Ependymin-like 1. (213 aa)
	epdr1	Ependymin related 1. (212 aa)
	kcnq1	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (631 aa)
	ENSPREP00000010219	Calponin-homology (CH) domain-containing protein. (125 aa)
	Limch1	DUF4757 domain-containing protein. (156 aa)
	scn1b	Sodium channel, voltage-gated, type I, beta b. (223 aa)
	LOC103460865	Coiled-coil domain containing 88C. (1316 aa)
	Kcne4	Potassium voltage-gated channel, Isk-related family, member 4. (185 aa)
	nup155	Nucleoporin 155. (1373 aa)
	LOC103467339	Myosin, light chain 6, alkali, smooth muscle and non-muscle. (212 aa)
	LOC103465374	Uncharacterized protein. (151 aa)
	LOC103475740	Sodium channel, voltage-gated, type IV, beta b. (213 aa)
	scn3b	Sodium channel, voltage-gated, type III, beta. (216 aa)
	frmd1	FERM domain-containing protein. (531 aa)
	frmd6	FERM domain containing 6. (607 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000010219	Limch1	ENSPREP00000010219	ENSPREP00000010243	Calponin-homology (CH) domain-containing protein.	DUF4757 domain-containing protein.	0.899
ENSPREP00000024223	ENSPREP00000028578	ENSPREP00000024223	ENSPREP00000028578	Uncharacterized protein.	Ion_trans domain-containing protein; Belongs to the potassium channel family.	0.787
ENSPREP00000024223	Kcne4	ENSPREP00000024223	ENSPREP00000015593	Uncharacterized protein.	Potassium voltage-gated channel, Isk-related family, member 4.	0.468
ENSPREP00000024223	kcnq1	ENSPREP00000024223	ENSPREP00000005330	Uncharacterized protein.	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.	0.787
ENSPREP00000024427	LOC103474422	ENSPREP00000024427	ENSPREP00000025599	IGv domain-containing protein.	Sodium channel, voltage-gated, type II, beta.	0.884
ENSPREP00000024427	LOC103474423	ENSPREP00000024427	ENSPREP00000025615	IGv domain-containing protein.	Sodium channel, voltage-gated, type IV, beta a.	0.952
ENSPREP00000024427	LOC103475740	ENSPREP00000024427	ENSPREP00000031857	IGv domain-containing protein.	Sodium channel, voltage-gated, type IV, beta b.	0.917
ENSPREP00000024427	scn1b	ENSPREP00000024427	ENSPREP00000013607	IGv domain-containing protein.	Sodium channel, voltage-gated, type I, beta b.	0.910
ENSPREP00000024427	scn3b	ENSPREP00000024427	ENSPREP00000032918	IGv domain-containing protein.	Sodium channel, voltage-gated, type III, beta.	0.465
ENSPREP00000028578	ENSPREP00000024223	ENSPREP00000028578	ENSPREP00000024223	Ion_trans domain-containing protein; Belongs to the potassium channel family.	Uncharacterized protein.	0.787
ENSPREP00000028578	Kcne4	ENSPREP00000028578	ENSPREP00000015593	Ion_trans domain-containing protein; Belongs to the potassium channel family.	Potassium voltage-gated channel, Isk-related family, member 4.	0.654
Kcne4	ENSPREP00000024223	ENSPREP00000015593	ENSPREP00000024223	Potassium voltage-gated channel, Isk-related family, member 4.	Uncharacterized protein.	0.468
Kcne4	ENSPREP00000028578	ENSPREP00000015593	ENSPREP00000028578	Potassium voltage-gated channel, Isk-related family, member 4.	Ion_trans domain-containing protein; Belongs to the potassium channel family.	0.654
Kcne4	kcnq1	ENSPREP00000015593	ENSPREP00000005330	Potassium voltage-gated channel, Isk-related family, member 4.	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.	0.654
LOC103465374	LOC103467339	ENSPREP00000024706	ENSPREP00000031613	Uncharacterized protein.	Myosin, light chain 6, alkali, smooth muscle and non-muscle.	0.900
LOC103467339	LOC103465374	ENSPREP00000031613	ENSPREP00000024706	Myosin, light chain 6, alkali, smooth muscle and non-muscle.	Uncharacterized protein.	0.900
LOC103474422	ENSPREP00000024427	ENSPREP00000025599	ENSPREP00000024427	Sodium channel, voltage-gated, type II, beta.	IGv domain-containing protein.	0.884
LOC103474422	LOC103474423	ENSPREP00000025599	ENSPREP00000025615	Sodium channel, voltage-gated, type II, beta.	Sodium channel, voltage-gated, type IV, beta a.	0.574
LOC103474422	scn1b	ENSPREP00000025599	ENSPREP00000013607	Sodium channel, voltage-gated, type II, beta.	Sodium channel, voltage-gated, type I, beta b.	0.884
LOC103474422	scn3b	ENSPREP00000025599	ENSPREP00000032918	Sodium channel, voltage-gated, type II, beta.	Sodium channel, voltage-gated, type III, beta.	0.776