(11 nodes) Necroptotic process network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000002275	DED domain-containing protein. (147 aa)
	ENSPREP00000002926	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (196 aa)
	LOC103477745	Tumor necrosis factor b (TNF superfamily, member 2). (249 aa)
	ipmk	Kinase; Belongs to the inositol phosphokinase (IPK) family. (472 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (924 aa)
	LOC103463417	Cylindromatosis (turban tumor syndrome), like. (616 aa)
	ENSPREP00000020797	TNFR-Cys domain-containing protein. (307 aa)
	LOC103466013	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (443 aa)
	itpk1	Inositol-tetrakisphosphate 1-kinase b. (393 aa)
	LOC103470751	Protein kinase domain-containing protein. (488 aa)
	LOC103465561	Cylindromatosis (turban tumor syndrome), b. (715 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002275	ENSPREP00000002926	ENSPREP00000002275	ENSPREP00000002926	DED domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.959
ENSPREP00000002275	ENSPREP00000020797	ENSPREP00000002275	ENSPREP00000020797	DED domain-containing protein.	TNFR-Cys domain-containing protein.	0.997
ENSPREP00000002275	LOC103463417	ENSPREP00000002275	ENSPREP00000013219	DED domain-containing protein.	Cylindromatosis (turban tumor syndrome), like.	0.624
ENSPREP00000002275	LOC103465561	ENSPREP00000002275	ENSPREP00000032899	DED domain-containing protein.	Cylindromatosis (turban tumor syndrome), b.	0.624
ENSPREP00000002275	LOC103466013	ENSPREP00000002275	ENSPREP00000021307	DED domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.991
ENSPREP00000002275	LOC103470751	ENSPREP00000002275	ENSPREP00000027001	DED domain-containing protein.	Protein kinase domain-containing protein.	0.671
ENSPREP00000002275	cyld	ENSPREP00000002275	ENSPREP00000010113	DED domain-containing protein.	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	0.624
ENSPREP00000002926	ENSPREP00000002275	ENSPREP00000002926	ENSPREP00000002275	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	DED domain-containing protein.	0.959
ENSPREP00000002926	ENSPREP00000020797	ENSPREP00000002926	ENSPREP00000020797	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	TNFR-Cys domain-containing protein.	0.985
ENSPREP00000002926	LOC103466013	ENSPREP00000002926	ENSPREP00000021307	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.507
ENSPREP00000020797	ENSPREP00000002275	ENSPREP00000020797	ENSPREP00000002275	TNFR-Cys domain-containing protein.	DED domain-containing protein.	0.997
ENSPREP00000020797	ENSPREP00000002926	ENSPREP00000020797	ENSPREP00000002926	TNFR-Cys domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.985
ENSPREP00000020797	LOC103466013	ENSPREP00000020797	ENSPREP00000021307	TNFR-Cys domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.529
LOC103463417	ENSPREP00000002275	ENSPREP00000013219	ENSPREP00000002275	Cylindromatosis (turban tumor syndrome), like.	DED domain-containing protein.	0.624
LOC103463417	LOC103466013	ENSPREP00000013219	ENSPREP00000021307	Cylindromatosis (turban tumor syndrome), like.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.479
LOC103465561	ENSPREP00000002275	ENSPREP00000032899	ENSPREP00000002275	Cylindromatosis (turban tumor syndrome), b.	DED domain-containing protein.	0.624
LOC103465561	LOC103466013	ENSPREP00000032899	ENSPREP00000021307	Cylindromatosis (turban tumor syndrome), b.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.479
LOC103465561	cyld	ENSPREP00000032899	ENSPREP00000010113	Cylindromatosis (turban tumor syndrome), b.	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	0.907
LOC103466013	ENSPREP00000002275	ENSPREP00000021307	ENSPREP00000002275	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DED domain-containing protein.	0.991
LOC103466013	ENSPREP00000002926	ENSPREP00000021307	ENSPREP00000002926	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.507