(22 nodes) Triglyceride homeostasis network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sirt1	Sirtuin 1. (677 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (485 aa)
	IL18	Uncharacterized protein. (218 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (490 aa)
	ENSPREP00000017976	Spexin hormone. (157 aa)
	MTLN	Mitoregulin. (56 aa)
	LOC103463345	Fibrinogen C-terminal domain-containing protein. (433 aa)
	LOC103459460	Patatin-like phospholipase domain containing 8. (747 aa)
	LOC103467002	Nuclear receptor subfamily 1, group H, member 5. (494 aa)
	angptl4	Angiopoietin-like 4. (462 aa)
	LOC103465828	PNPLA domain-containing protein. (828 aa)
	gckr	Uncharacterized protein. (599 aa)
	LOC103474828	Apolipoprotein A-Ib. (263 aa)
	ENSPREP00000010762	Uncharacterized protein. (165 aa)
	LOC103479015	Fibrinogen C-terminal domain-containing protein. (471 aa)
	ENSPREP00000006573	Uncharacterized protein. (161 aa)
	xbp1	X-box binding protein 1. (385 aa)
	abcg5	ATP-binding cassette, sub-family G (WHITE), member 5. (608 aa)
	abcg8	ATP-binding cassette, sub-family G (WHITE), member 8. (669 aa)
	LOC103463466	Uncharacterized protein. (211 aa)
	pla2g12b	Phospholipase A2, group XIIB. (204 aa)
	angptl3	Angiopoietin-like 3. (466 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000010762	LOC103479015	ENSPREP00000010762	ENSPREP00000007233	Uncharacterized protein.	Fibrinogen C-terminal domain-containing protein.	0.522
ENSPREP00000010762	angptl3	ENSPREP00000010762	ENSPREP00000030963	Uncharacterized protein.	Angiopoietin-like 3.	0.617
LOC103463345	angptl4	ENSPREP00000016396	ENSPREP00000012938	Fibrinogen C-terminal domain-containing protein.	Angiopoietin-like 4.	0.903
LOC103463466	LOC103474828	ENSPREP00000004853	ENSPREP00000010904	Uncharacterized protein.	Apolipoprotein A-Ib.	0.656
LOC103463466	pla2g12b	ENSPREP00000004853	ENSPREP00000034205	Uncharacterized protein.	Phospholipase A2, group XIIB.	0.902
LOC103467002	abcg5	ENSPREP00000014015	ENSPREP00000005423	Nuclear receptor subfamily 1, group H, member 5.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.493
LOC103467002	abcg8	ENSPREP00000014015	ENSPREP00000005357	Nuclear receptor subfamily 1, group H, member 5.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.475
LOC103474828	LOC103463466	ENSPREP00000010904	ENSPREP00000004853	Apolipoprotein A-Ib.	Uncharacterized protein.	0.656
LOC103474828	abcg5	ENSPREP00000010904	ENSPREP00000005423	Apolipoprotein A-Ib.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.560
LOC103474828	abcg8	ENSPREP00000010904	ENSPREP00000005357	Apolipoprotein A-Ib.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.516
LOC103474828	pla2g12b	ENSPREP00000010904	ENSPREP00000034205	Apolipoprotein A-Ib.	Phospholipase A2, group XIIB.	0.423
LOC103474828	scarb1	ENSPREP00000010904	ENSPREP00000021860	Apolipoprotein A-Ib.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.554
LOC103479015	ENSPREP00000010762	ENSPREP00000007233	ENSPREP00000010762	Fibrinogen C-terminal domain-containing protein.	Uncharacterized protein.	0.522
abcg5	LOC103467002	ENSPREP00000005423	ENSPREP00000014015	ATP-binding cassette, sub-family G (WHITE), member 5.	Nuclear receptor subfamily 1, group H, member 5.	0.493
abcg5	LOC103474828	ENSPREP00000005423	ENSPREP00000010904	ATP-binding cassette, sub-family G (WHITE), member 5.	Apolipoprotein A-Ib.	0.560
abcg5	abcg8	ENSPREP00000005423	ENSPREP00000005357	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.998
abcg5	nr1h4	ENSPREP00000005423	ENSPREP00000026448	ATP-binding cassette, sub-family G (WHITE), member 5.	Nuclear receptor subfamily 1, group H, member 4.	0.534
abcg8	LOC103467002	ENSPREP00000005357	ENSPREP00000014015	ATP-binding cassette, sub-family G (WHITE), member 8.	Nuclear receptor subfamily 1, group H, member 5.	0.475
abcg8	LOC103474828	ENSPREP00000005357	ENSPREP00000010904	ATP-binding cassette, sub-family G (WHITE), member 8.	Apolipoprotein A-Ib.	0.516
abcg8	abcg5	ENSPREP00000005357	ENSPREP00000005423	ATP-binding cassette, sub-family G (WHITE), member 8.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.998