(5 nodes) Type 1 melanocortin receptor binding network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000002541	Agouti domain-containing protein. (163 aa)
	LOC103472811	Uncharacterized protein. (209 aa)
	Mrap	Uncharacterized protein. (63 aa)
	POMC	Proopiomelanocortin. (205 aa)
	mrap2	Melanocortin 2 receptor accessory protein 2b. (229 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002541	LOC103472811	ENSPREP00000002541	ENSPREP00000031135	Agouti domain-containing protein.	Uncharacterized protein.	0.527
ENSPREP00000002541	POMC	ENSPREP00000002541	ENSPREP00000019746	Agouti domain-containing protein.	Proopiomelanocortin.	0.527
ENSPREP00000002541	mrap2	ENSPREP00000002541	ENSPREP00000009430	Agouti domain-containing protein.	Melanocortin 2 receptor accessory protein 2b.	0.442
LOC103472811	ENSPREP00000002541	ENSPREP00000031135	ENSPREP00000002541	Uncharacterized protein.	Agouti domain-containing protein.	0.527
LOC103472811	Mrap	ENSPREP00000031135	ENSPREP00000019944	Uncharacterized protein.	Uncharacterized protein.	0.824
Mrap	LOC103472811	ENSPREP00000019944	ENSPREP00000031135	Uncharacterized protein.	Uncharacterized protein.	0.824
Mrap	POMC	ENSPREP00000019944	ENSPREP00000019746	Uncharacterized protein.	Proopiomelanocortin.	0.824
POMC	ENSPREP00000002541	ENSPREP00000019746	ENSPREP00000002541	Proopiomelanocortin.	Agouti domain-containing protein.	0.527
POMC	Mrap	ENSPREP00000019746	ENSPREP00000019944	Proopiomelanocortin.	Uncharacterized protein.	0.824
mrap2	ENSPREP00000002541	ENSPREP00000009430	ENSPREP00000002541	Melanocortin 2 receptor accessory protein 2b.	Agouti domain-containing protein.	0.442