(28 nodes) Cellular response to interleukin-1 network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rbmx	RNA binding motif protein X-linked. (383 aa)
	LOC103469458	Nuclear receptor subfamily 1, group d, member 1. (523 aa)
	LOC103470686	Interleukin-1. (247 aa)
	ENSPREP00000019776	C-C motif chemokine. (110 aa)
	rps6ka5	Ribosomal protein S6 kinase. (810 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1119 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (418 aa)
	LOC103467373	Nuclear receptor subfamily 1, group D, member 4a. (585 aa)
	tnfrsf18	CD40 molecule, TNF receptor superfamily member 5. (314 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (871 aa)
	LOC103479265	SCY domain-containing protein. (151 aa)
	ENSPREP00000018760	Protein kinase domain-containing protein. (507 aa)
	ENSPREP00000002488	Uncharacterized protein. (425 aa)
	LOC103478334	Zmp:0000000936. (634 aa)
	LOC103478314	Zmp:0000000936. (635 aa)
	LOC103469798	SCY domain-containing protein. (110 aa)
	LOC103466287	SCY domain-containing protein. (143 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)
	ENSPREP00000005814	A kinase (PRKA) anchor protein 12b. (1314 aa)
	zc3h12a	Zinc finger CCCH-type containing 12A. (623 aa)
	LOC103476173	Ribosomal protein S6 kinase. (758 aa)
	ENSPREP00000008909	SCY domain-containing protein. (88 aa)
	LOC103470500	NK3 homeobox 1. (196 aa)
	acod1	Aconitate decarboxylase 1. (531 aa)
	ENSPREP00000010947	Uncharacterized protein. (306 aa)
	tank	TRAF family member-associated NFKB activator. (338 aa)
	ST18	ST18 C2H2C-type zinc finger transcription factor. (1139 aa)
	ENSPREP00000014507	UBA_6 domain-containing protein. (200 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002488	ENSPREP00000018760	ENSPREP00000002488	ENSPREP00000018760	Uncharacterized protein.	Protein kinase domain-containing protein.	0.723
ENSPREP00000002488	LOC103470686	ENSPREP00000002488	ENSPREP00000019387	Uncharacterized protein.	Interleukin-1.	0.889
ENSPREP00000002488	traf6	ENSPREP00000002488	ENSPREP00000005082	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.744
ENSPREP00000008909	ENSPREP00000019776	ENSPREP00000008909	ENSPREP00000019776	SCY domain-containing protein.	C-C motif chemokine.	0.529
ENSPREP00000014507	rc3h1	ENSPREP00000014507	ENSPREP00000025906	UBA_6 domain-containing protein.	Ring finger and CCCH-type domains 1b.	0.406
ENSPREP00000014507	tank	ENSPREP00000014507	ENSPREP00000011950	UBA_6 domain-containing protein.	TRAF family member-associated NFKB activator.	0.548
ENSPREP00000018760	ENSPREP00000002488	ENSPREP00000018760	ENSPREP00000002488	Protein kinase domain-containing protein.	Uncharacterized protein.	0.723
ENSPREP00000018760	LOC103470686	ENSPREP00000018760	ENSPREP00000019387	Protein kinase domain-containing protein.	Interleukin-1.	0.767
ENSPREP00000018760	LOC103478314	ENSPREP00000018760	ENSPREP00000002730	Protein kinase domain-containing protein.	Zmp:0000000936.	0.723
ENSPREP00000018760	LOC103478334	ENSPREP00000018760	ENSPREP00000002646	Protein kinase domain-containing protein.	Zmp:0000000936.	0.723
ENSPREP00000018760	map2k7	ENSPREP00000018760	ENSPREP00000027032	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase 7.	0.450
ENSPREP00000018760	traf6	ENSPREP00000018760	ENSPREP00000005082	Protein kinase domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.996
ENSPREP00000019776	ENSPREP00000008909	ENSPREP00000019776	ENSPREP00000008909	C-C motif chemokine.	SCY domain-containing protein.	0.529
ENSPREP00000019776	LOC103466287	ENSPREP00000019776	ENSPREP00000003974	C-C motif chemokine.	SCY domain-containing protein.	0.529
ENSPREP00000019776	LOC103469798	ENSPREP00000019776	ENSPREP00000003597	C-C motif chemokine.	SCY domain-containing protein.	0.821
ENSPREP00000019776	LOC103479265	ENSPREP00000019776	ENSPREP00000019003	C-C motif chemokine.	SCY domain-containing protein.	0.502
LOC103466287	ENSPREP00000019776	ENSPREP00000003974	ENSPREP00000019776	SCY domain-containing protein.	C-C motif chemokine.	0.529
LOC103469798	ENSPREP00000019776	ENSPREP00000003597	ENSPREP00000019776	SCY domain-containing protein.	C-C motif chemokine.	0.821
LOC103470686	ENSPREP00000002488	ENSPREP00000019387	ENSPREP00000002488	Interleukin-1.	Uncharacterized protein.	0.889
LOC103470686	ENSPREP00000018760	ENSPREP00000019387	ENSPREP00000018760	Interleukin-1.	Protein kinase domain-containing protein.	0.767