(10 nodes) Cellular response to estrogen stimulus network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sra1	Uncharacterized protein. (273 aa)
	pelp1	Proline, glutamate and leucine rich protein 1. (1272 aa)
	hpx	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (446 aa)
	LOC103470539	AT rich interactive domain 5A (MRF1-like). (589 aa)
	LOC103470076	Uncharacterized protein. (381 aa)
	LOC103464167	Vitellogenin 3, phosvitinless. (1264 aa)
	bcas3	BCAS3 microtubule associated cell migration factor. (666 aa)
	crhbp	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (323 aa)
	LOC103475709	Androgen receptor. (757 aa)
	ar	Androgen receptor. (685 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464167	LOC103475709	ENSPREP00000020196	ENSPREP00000030777	Vitellogenin 3, phosvitinless.	Androgen receptor.	0.459
LOC103464167	ar	ENSPREP00000020196	ENSPREP00000031253	Vitellogenin 3, phosvitinless.	Androgen receptor.	0.459
LOC103475709	LOC103464167	ENSPREP00000030777	ENSPREP00000020196	Androgen receptor.	Vitellogenin 3, phosvitinless.	0.459
LOC103475709	ar	ENSPREP00000030777	ENSPREP00000031253	Androgen receptor.	Androgen receptor.	0.902
ar	LOC103464167	ENSPREP00000031253	ENSPREP00000020196	Androgen receptor.	Vitellogenin 3, phosvitinless.	0.459
ar	LOC103475709	ENSPREP00000031253	ENSPREP00000030777	Androgen receptor.	Androgen receptor.	0.902