STRINGSTRING
LOC103479188 LOC103479188 acaca acaca ENSPREP00000002631 ENSPREP00000002631 LOC103468105 LOC103468105 ACSL1 ACSL1 LOC103479605 LOC103479605 LOC103475331 LOC103475331 acsl1 acsl1 ppcs ppcs LOC103470507 LOC103470507 ENSPREP00000014189 ENSPREP00000014189 LOC103463607 LOC103463607 mpc2 mpc2 acss2 acss2 elovl6 elovl6 LOC103463592 LOC103463592 ACLY ACLY pdha1 pdha1 ENSPREP00000016743 ENSPREP00000016743 LOC103457721 LOC103457721 LOC103478339 LOC103478339 LOC103477396 LOC103477396 GCDH GCDH elovl7 elovl7 dlat dlat pdhx pdhx LOC103457587 LOC103457587 mlycd mlycd LOC103475425 LOC103475425 LOC103475424 LOC103475424 elovl5 elovl5 LOC103481260 LOC103481260 acacb acacb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103479188Elongation of very long chain fatty acids protein. (305 aa)
acacaAcetyl-CoA carboxylase alpha. (2251 aa)
ENSPREP00000002631ACAS_N domain-containing protein. (115 aa)
LOC103468105Acyl-CoA synthetase short chain family member 2. (376 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (691 aa)
LOC103479605Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (312 aa)
LOC103475331AMP-binding domain-containing protein. (685 aa)
acsl1Acyl-CoA synthetase long chain family member 1a. (698 aa)
ppcsPhosphopantothenoylcysteine synthetase. (322 aa)
LOC103470507Acyl-CoA synthetase long chain family member 2. (699 aa)
ENSPREP00000014189Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (202 aa)
LOC103463607Elongation of very long chain fatty acids protein. (248 aa)
mpc2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (123 aa)
acss2Acetyl-coenzyme A synthetase. (669 aa)
elovl6Elongation of very long chain fatty acids protein. (312 aa)
LOC103463592Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (407 aa)
ACLYATP citrate lyase. (1056 aa)
pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
ENSPREP00000016743Uncharacterized protein. (269 aa)
LOC103457721Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (304 aa)
LOC103478339Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (320 aa)
LOC103477396Elongation of very long chain fatty acids protein. (283 aa)
GCDHGlutaryl-CoA dehydrogenase b. (447 aa)
elovl7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (294 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (643 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (493 aa)
LOC103457587Acetyl-coenzyme A synthetase. (680 aa)
mlycdMalonyl-CoA decarboxylase. (503 aa)
LOC103475425Uncharacterized protein. (609 aa)
LOC103475424Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
elovl5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (294 aa)
LOC103481260ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1121 aa)
acacbAcetyl-CoA carboxylase beta. (2054 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.