15 items (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103468546	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (220 aa)
	LOC103477155	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (560 aa)
	pkd1	Polycystic kidney disease 1a. (4592 aa)
	LOC103466359	WT1 transcription factor a. (356 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	aqp1	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (268 aa)
	ENSPREP00000010780	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (176 aa)
	LOC103478374	Iroquois homeobox 1a. (496 aa)
	tcf21	Transcription factor 21. (175 aa)
	nphs2	NPHS2 stomatin family member, podocin. (376 aa)
	wt1	WT1 transcription factor b. (490 aa)
	LOC103472063	Homeobox domain-containing protein. (432 aa)
	ENSPREP00000027807	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (393 aa)
	GREM1	Gremlin. (182 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103466359	nphs2	ENSPREP00000001815	ENSPREP00000017977	WT1 transcription factor a.	NPHS2 stomatin family member, podocin.	0.483
LOC103466359	tcf21	ENSPREP00000001815	ENSPREP00000016457	WT1 transcription factor a.	Transcription factor 21.	0.452
nphs2	LOC103466359	ENSPREP00000017977	ENSPREP00000001815	NPHS2 stomatin family member, podocin.	WT1 transcription factor a.	0.483
nphs2	wt1	ENSPREP00000017977	ENSPREP00000020243	NPHS2 stomatin family member, podocin.	WT1 transcription factor b.	0.483
tcf21	LOC103466359	ENSPREP00000016457	ENSPREP00000001815	Transcription factor 21.	WT1 transcription factor a.	0.452
tcf21	wt1	ENSPREP00000016457	ENSPREP00000020243	Transcription factor 21.	WT1 transcription factor b.	0.452
wt1	nphs2	ENSPREP00000020243	ENSPREP00000017977	WT1 transcription factor b.	NPHS2 stomatin family member, podocin.	0.483
wt1	tcf21	ENSPREP00000020243	ENSPREP00000016457	WT1 transcription factor b.	Transcription factor 21.	0.452